Adenosine 5'-monophosphate disodium salt

Product Name: Adenosine 5'-monophosphate disodium salt
CAS No.: 4578-31-8
Chemical Name: Adenosine 5'-monophosphate disodium salt
Synonyms: AMP disodium;ADENOSINE 5'-MONOPHOSPHATE SODIUM SALT;ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT;ADENOSINE 5'-MONOPHOSPHORIC ACID SODIUM SALT;AMP, 2NA;AMP, NA2;5'-AMP 2NA;5'-AMP-Na2;5'-AMP，2Na;Disodium AMP
CBNumber: CB7197600
Molecular Formula: C10H15N5NaO7P
Formula Weight: 371.22
MOL File: 4578-31-8.mol

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Adenosine 5'-monophosphate disodium salt Property

Melting point:: 232-235°C
FEMA: 4224 | ADENOSINE MONOPHOSPHATE; MONOSODIUM, OR DISODIUM ADENYLATE
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: H₂O: soluble
form: crystalline
color: White
Odor: Odorless
biological source: microbial (Candida utilis)
synthetic
optical activity: [α]20/D 43±2°, c = 1% in 0.5 M Na2HPO4 (dry matter)
Water Solubility: Soluble in water, dimethyl sulfoxide and methanol.
BRN: 3586732
Stability:: Hygroscopic
InChIKey: PUKWBWWOVFJXQS-JHVGCDEENA-N
SMILES: O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O.[NaH] |&1:1,2,3,11,r|
CAS DataBase Reference: 4578-31-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-36-26
WGK Germany: 3
RTECS: AU7481600
F: 1-10
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 01930
Product name: Adenosine 5′-monophosphate disodium salt
Purity: ≥99.0% (HPLC)
Packaging: 5g
Price: $113
Updated: 2025/07/31

Sigma-Aldrich

Product number: 01930
Product name: Adenosine 5′-monophosphate disodium salt
Purity: ≥99.0% (HPLC)
Packaging: 25g
Price: $447
Updated: 2025/07/31

Sigma-Aldrich

Product number: 118110
Product name: Adenosine 5ʹ-Monophosphate, Disodium Salt - CAS 4578-31-8 - Calbiochem
Packaging: 5G
Price: $151
Updated: 2022/05/15

TCI Chemical

Product number: A2117
Product name: Adenosine 5'-Monophosphate Disodium Salt
Packaging: 25G
Price: $73
Updated: 2025/07/31

TRC

Product number: A281790
Product name: Adenosine-5'-monophosphate disodium salt
Packaging: 5g
Price: $80
Updated: 2021/12/16

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Adenosine 5'-monophosphate disodium salt Chemical Properties,Usage,Production

Description

Adenosine 5'-monophosphate disodium salt is a modified phosphoramidite used for the synthesis of deoxyribonucleosides and nucleosides. Adenosine 5'-monophosphate disodium salt is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). It may be used as a substrate by a variety of enzymes such as AMP-thymidine kinase, AMP deaminase and 5?-nucleotidase.

Chemical Properties

White powder

Uses

Adenosine-5'-monophosphate disodium salt is a nucleotide involved in the reactions of cellular energy transfers. It is useful for skin rejuvenation in dermatology and aesthetic dermatology. It acts as an activator of a class of protein kinases called as AMP-activated protein kinase (AMPK). Further, it is used as a substrate for enzymes such as AMP-thymidine kinase, AMP deaminase and 5'-nucleotidase.

Uses

Adenosine 5'-monophosphate disodium salt is useful for skin rejuvenation in dermatology and aesthetic dermatology.

Definition

ChEBI: Adenosine 5'-phosphate disodium is an organic molecular entity.

Biological Functions

Research indicates that an emulsion containing 3% Adenosine 5'-monophosphate disodium salt (AMP-NA2) safely accelerates human stratum corneum renewal. AMP-Na₂ exhibits dual characteristics in the proliferation of primary cultured keratinocytes: inducing cell growth at low concentrations whilst inhibiting it at high concentrations. It further promotes cell cycle progression in the basal layer of hairless rat epidermis. Research suggests topical AMP-Na₂ achieves mild penetration into the epidermal basal layer, where its low-concentration environment facilitates cell cycle advancement.
[1] FUKUMI FURUKAWA. Effects of adenosine 5′-monophosphate on epidermal turnover[J]. Archives of Dermatological Research, 2008, 300 9: 485-493. DOI:10.1007/s00403-008-0882-x.

General Description

Adenosine 5'-monophosphate disodium salt(AMP-2Na) is an orally active purine nucleotide, and participates in ATP metabolism. AMP-2Na is also a ligand for adenosine 2B receptor. AMP-2Na can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. AMP-2Na can be used for research of diabetes.

Adenosine 5'-monophosphate disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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Adenosine 5'-monophosphate disodium salt Suppliers

Australia 1 Canada 3 China 446 Europe 3 Germany 8 India 21 Japan 1 Poland 1 Switzerland 3 United Kingdom 8 United States 40 Global 535

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View Lastest Price from Adenosine 5'-monophosphate disodium salt manufacturers

WeiTai BioPharmaceutical Co.,Ltd(Hangzhou?)

Product: Adenosine 5'-monophosphate disodium salt（AMP-NA2） 4578-31-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20T
Release date: 2025-08-19

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Adenosine 5'-monophosphate disodium salt 4578-31-8
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%min
Supply Ability: 500kg
Release date: 2021-12-09

Hebei Chuanghai Biotechnology Co., Ltd

Product: Adenosine 5’-monophosphate disodium salt 4578-31-8
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-05

4578-31-8, Adenosine 5'-monophosphate disodium saltRelated Search:

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5’-adenylicacid,disodiumsalt

adenylicaciddisodiumsalt

disodium5’-amp

ADENOSINE-5-MONOPHOSPHATENA2

ADENOSINE-5''-MONOPHOSPHATE DISODIUM SALT (AMP)

ADENOSINE-5-MONO PHOSPHATE DISODIUM SALT (AMP-Na2) extrapure for biochemistry

AMP disodium

Disodium AMP

disodium [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate

disodium [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphate

disodium [(2R,3S,4R,5R)-5-(6-azanylpurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl phosphate

-monophosphate(AMP),disodium,hexahydrate

ADENOSINE-5'-MONOPHOSPHATE(AMP), DISODIUM, HEXAHYDRATE

Disodium adenosine 5

ADENOSINE-5'-PHOSPHATE.NA2-SALT ANALYTICAL GRADE

Adenosine 5′-monophosphate disodium salt,5′-AMP-Na2

SodiuM ((2R,3S,4R,5R)-5-(6-aMino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl phosphate

Adenosine AMP 5'-Monophosphoric acid disodiuM salt

5'-ADENYLIC ACID SODIUM SALT

5-ADENYLIC ACID, SODIUM SALT

5'-AMP 2NA

5'-AMP DISODIUM SALT

5'-AMP SODIUM SALT

disodium adenosine 5'-phosphate

disodium adenosine 5'-phosphate hydrate

5'-AMP-Na2 salt

AMP, 2NA

AMP DISODIUM SALT

AMP SODIUM SALT

AMP, NA2

A-5'-P SODIUM SALT

ADENOSINE 5'-MONOPHOSPHORIC ACID SODIUM SALT

ADENOSINE-5'-MONOPHOSPHORIC ACID, DISODIUM

ADENOSINE 5'-MONOPHOSPHORIC ACID DISODIUM SALT

ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT

ADENOSINE 5'-MONOPHOSPHATE SODIUM SALT

ADENOSINE-5'-PHOSPHATE, DISODIUM SALT

ADENOSINE-5'-PHOSPHATE NA2-SALT

ADENOSINE MONOPHOSPHATE DINA SALT

Adenosine 5'-monophosphate disodium salt dihydrate

Adenosine 5'-monophosphate disodium salt dihydrate;Adenosine-5'-monophosphoric acid Na2 salt;5'-Adenylic acid disodium salt;t-Adenylic acid disodium salt;5'-AMP-Na2 salt;Muscle adenylic acid disodium salt

Adenosine-5'-monophosphoric acid Na2 salt

Muscle adenylic acid disodium salt

t-Adenylic acid disodium salt

Adenosine5-MonophosphoricAcidSodiumSalt(Amp)

ADENOSINE-5-MONOPHOSPHORIC ACID SODIUIM SALT (A.M.P.)

5'-Adenosine Monophosphate Disodium Salt

5'-Adenylic acid,sodiuM salt (1:2)

DisodiuM 5'-adenine nucleotide

BENZOIC ACID ACS GRADE

Adenosine-5'-monophosphate disodium salt hexahydrate

Adenosine 5'-phosphate disodium

ADENOSINE MONOPHOSPHATE: MONOSODIUM, OR DISODIUM ADENYLATE

Adenosine 5'-monophosphoric acid disodium salt dih

Disodium adenosine 5'-phosphate (AMP-2Na)

Adenosine -5'- Monophosphate Disodium Salt（AMP-Na2）

AMP-Na,5-AMP-Na

Adenosine 5'-monophosphate disodium sal