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Adenosine 5'-monophosphate disodium salt

Product Name
Adenosine 5'-monophosphate disodium salt
CAS No.
4578-31-8
Chemical Name
Adenosine 5'-monophosphate disodium salt
Synonyms
AMP disodium;ADENOSINE 5'-MONOPHOSPHATE SODIUM SALT;ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT;ADENOSINE 5'-MONOPHOSPHORIC ACID SODIUM SALT;AMP, 2NA;AMP, NA2;5'-AMP 2NA;5'-AMP-Na2;5'-AMP，2Na;Disodium AMP
CBNumber
CB7197600
Molecular Formula
C10H15N5NaO7P
Formula Weight
371.22
MOL File
4578-31-8.mol
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Adenosine 5'-monophosphate disodium salt Property

Melting point:
232-235°C
FEMA 
4224 | ADENOSINE MONOPHOSPHATE; MONOSODIUM, OR DISODIUM ADENYLATE
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
H2O: soluble
form 
crystalline
color 
White
Odor
Odorless
biological source
microbial (Candida utilis)
synthetic
optical activity
[α]20/D 43±2°, c = 1% in 0.5 M Na2HPO4 (dry matter)
Water Solubility 
Soluble in water, dimethyl sulfoxide and methanol.
BRN 
3586732
Stability:
Hygroscopic
InChIKey
PUKWBWWOVFJXQS-JHVGCDEENA-N
SMILES
O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O.[NaH] |&1:1,2,3,11,r|
CAS DataBase Reference
4578-31-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
RTECS 
AU7481600
F 
1-10
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
01930
Product name
Adenosine 5′-monophosphate disodium salt
Purity
≥99.0% (HPLC)
Packaging
5g
Price
$113
Updated
2025/07/31
Sigma-Aldrich
Product number
01930
Product name
Adenosine 5′-monophosphate disodium salt
Purity
≥99.0% (HPLC)
Packaging
25g
Price
$447
Updated
2025/07/31
Sigma-Aldrich
Product number
118110
Product name
Adenosine 5ʹ-Monophosphate, Disodium Salt - CAS 4578-31-8 - Calbiochem
Packaging
5G
Price
$151
Updated
2022/05/15
TCI Chemical
Product number
A2117
Product name
Adenosine 5'-Monophosphate Disodium Salt
Packaging
25G
Price
$73
Updated
2025/07/31
TRC
Product number
A281790
Product name
Adenosine-5'-monophosphate disodium salt
Packaging
5g
Price
$80
Updated
2021/12/16
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Adenosine 5'-monophosphate disodium salt Chemical Properties,Usage,Production

Description

Adenosine 5'-monophosphate disodium salt is a modified phosphoramidite used for the synthesis of deoxyribonucleosides and nucleosides. Adenosine 5'-monophosphate disodium salt is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). It may be used as a substrate by a variety of enzymes such as AMP-thymidine kinase, AMP deaminase and 5?-nucleotidase.

Chemical Properties

White powder

Uses

Adenosine-5'-monophosphate disodium salt is a nucleotide involved in the reactions of cellular energy transfers. It is useful for skin rejuvenation in dermatology and aesthetic dermatology. It acts as an activator of a class of protein kinases called as AMP-activated protein kinase (AMPK). Further, it is used as a substrate for enzymes such as AMP-thymidine kinase, AMP deaminase and 5'-nucleotidase.

Uses

Adenosine 5'-monophosphate disodium salt is useful for skin rejuvenation in dermatology and aesthetic dermatology.

Definition

ChEBI: Adenosine 5'-phosphate disodium is an organic molecular entity.

Biological Functions

Research indicates that an emulsion containing 3% Adenosine 5'-monophosphate disodium salt (AMP-NA2) safely accelerates human stratum corneum renewal. AMP-Na₂ exhibits dual characteristics in the proliferation of primary cultured keratinocytes: inducing cell growth at low concentrations whilst inhibiting it at high concentrations. It further promotes cell cycle progression in the basal layer of hairless rat epidermis. Research suggests topical AMP-Na₂ achieves mild penetration into the epidermal basal layer, where its low-concentration environment facilitates cell cycle advancement.
[1] FUKUMI FURUKAWA. Effects of adenosine 5′-monophosphate on epidermal turnover[J]. Archives of Dermatological Research, 2008, 300 9: 485-493. DOI:10.1007/s00403-008-0882-x.

General Description

Adenosine 5'-monophosphate disodium salt(AMP-2Na) is an orally active purine nucleotide, and participates in ATP metabolism. AMP-2Na is also a ligand for adenosine 2B receptor. AMP-2Na can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. AMP-2Na can be used for research of diabetes.

Adenosine 5'-monophosphate disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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Adenosine 5'-monophosphate disodium salt Suppliers

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View Lastest Price from Adenosine 5'-monophosphate disodium salt manufacturers

WeiTai BioPharmaceutical Co.,Ltd(Hangzhou?)
Product
Adenosine 5'-monophosphate disodium salt（AMP-NA2） 4578-31-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20T
Release date
2025-08-19
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Adenosine 5'-monophosphate disodium salt 4578-31-8
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
500kg
Release date
2021-12-09
Hebei Chuanghai Biotechnology Co., Ltd
Product
Adenosine 5’-monophosphate disodium salt 4578-31-8
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-05

4578-31-8, Adenosine 5'-monophosphate disodium saltRelated Search:

Ethylenediaminetetraacetic acid disodium salt Disodium edetate dihydrate Zinc phosphate PUROMYCIN AMINONUCLEOSIDE Adenine Sulfate ADP ADENOSINE 5'-TRIPHOSPHATASE Adenosine5'-(tetrahydrogen triphosphate), disodiuM salt, trihydrate (9CI) Trisodium phosphate Adenosine 6-Chloropurine ribonucleoside Disodium nucleotide Vidarabine monophosphate NUCLEOSIDE PHOSPHORYLASE BACTERIAL Adenine 5'-Guanylic acid Adenosine 5'-monophosphate Cyclic AMP

  • 5’-adenylicacid,disodiumsalt
  • adenylicaciddisodiumsalt
  • disodium5’-amp
  • ADENOSINE-5-MONOPHOSPHATENA2
  • ADENOSINE-5''-MONOPHOSPHATE DISODIUM SALT (AMP)
  • ADENOSINE-5-MONO PHOSPHATE DISODIUM SALT (AMP-Na2) extrapure for biochemistry
  • AMP disodium
  • Disodium AMP
  • disodium [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
  • disodium [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphate
  • disodium [(2R,3S,4R,5R)-5-(6-azanylpurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl phosphate
  • -monophosphate(AMP),disodium,hexahydrate
  • ADENOSINE-5'-MONOPHOSPHATE(AMP), DISODIUM, HEXAHYDRATE
  • Disodium adenosine 5
  • ADENOSINE-5'-PHOSPHATE.NA2-SALT ANALYTICAL GRADE
  • Adenosine 5′-monophosphate disodium salt,5′-AMP-Na2
  • SodiuM ((2R,3S,4R,5R)-5-(6-aMino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl phosphate
  • Adenosine AMP 5'-Monophosphoric acid disodiuM salt
  • 5'-ADENYLIC ACID SODIUM SALT
  • 5-ADENYLIC ACID, SODIUM SALT
  • 5'-AMP 2NA
  • 5'-AMP DISODIUM SALT
  • 5'-AMP SODIUM SALT
  • disodium adenosine 5'-phosphate
  • disodium adenosine 5'-phosphate hydrate
  • 5'-AMP-Na2 salt
  • AMP, 2NA
  • AMP DISODIUM SALT
  • AMP SODIUM SALT
  • AMP, NA2
  • A-5'-P SODIUM SALT
  • ADENOSINE 5'-MONOPHOSPHORIC ACID SODIUM SALT
  • ADENOSINE-5'-MONOPHOSPHORIC ACID, DISODIUM
  • ADENOSINE 5'-MONOPHOSPHORIC ACID DISODIUM SALT
  • ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT
  • ADENOSINE 5'-MONOPHOSPHATE SODIUM SALT
  • ADENOSINE-5'-PHOSPHATE, DISODIUM SALT
  • ADENOSINE-5'-PHOSPHATE NA2-SALT
  • ADENOSINE MONOPHOSPHATE DINA SALT
  • Adenosine 5'-monophosphate disodium salt dihydrate
  • Adenosine 5'-monophosphate disodium salt dihydrate;Adenosine-5'-monophosphoric acid Na2 salt;5'-Adenylic acid disodium salt;t-Adenylic acid disodium salt;5'-AMP-Na2 salt;Muscle adenylic acid disodium salt
  • Adenosine-5'-monophosphoric acid Na2 salt
  • Muscle adenylic acid disodium salt
  • t-Adenylic acid disodium salt
  • Adenosine5-MonophosphoricAcidSodiumSalt(Amp)
  • ADENOSINE-5-MONOPHOSPHORIC ACID SODIUIM SALT (A.M.P.)
  • 5'-Adenosine Monophosphate Disodium Salt
  • 5'-Adenylic acid,sodiuM salt (1:2)
  • DisodiuM 5'-adenine nucleotide
  • BENZOIC ACID ACS GRADE
  • Adenosine-5'-monophosphate disodium salt hexahydrate
  • Adenosine 5'-phosphate disodium
  • ADENOSINE MONOPHOSPHATE: MONOSODIUM, OR DISODIUM ADENYLATE
  • Adenosine 5'-monophosphoric acid disodium salt dih
  • Disodium adenosine 5'-phosphate (AMP-2Na)
  • Adenosine -5'- Monophosphate Disodium Salt（AMP-Na2）
  • AMP-Na,5-AMP-Na
  • Adenosine 5'-monophosphate disodium sal