Tolperisone hydrochloride
- Product Name
- Tolperisone hydrochloride
- CAS No.
- 3644-61-9
- Chemical Name
- Tolperisone hydrochloride
- Synonyms
- Abbsa;n-553;Isocalm;Kineorl;muscalm;Atmosgen;Minacalm;midocalm;mydocalm;Arantoick
- CBNumber
- CB7200340
- Molecular Formula
- C16H24ClNO
- Formula Weight
- 281.82
- MOL File
- 3644-61-9.mol
Tolperisone hydrochloride Property
- Melting point:
- 181-183°C
- storage temp.
- room temp
- solubility
- H2O: >20mg/mL
- form
- solid
- color
- white
- PH
- pH(50g/l, 25℃) : 4.5~5.5
- Water Solubility
- almost transparency
- Merck
- 14,9522
- CAS DataBase Reference
- 3644-61-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-52/53-36/37/38
- Safety Statements
- 26-36-45-61-36/37-37/39
- WGK Germany
- 3
- RTECS
- UH1575500
- Toxicity
- LD50 s.c. in mice: 620 mg/kg (Porszasz, 1961)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- T3577
- Product name
- Tolperisone hydrochloride
- Purity
- ≥98% (HPLC), solid
- Packaging
- 50mg
- Price
- $144
- Updated
- 2024/03/01
- Product number
- T3577
- Product name
- Tolperisone hydrochloride
- Purity
- ≥98% (HPLC), solid
- Packaging
- 250mg
- Price
- $442
- Updated
- 2024/03/01
- Product number
- T1319
- Product name
- Tolperisone Hydrochloride
- Purity
- >99.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 26078
- Product name
- Tolperisone (hydrochloride)
- Packaging
- 1g
- Price
- $363
- Updated
- 2024/03/01
- Product number
- 26078
- Product name
- Tolperisone (hydrochloride)
- Packaging
- 5g
- Price
- $1085
- Updated
- 2024/03/01
Tolperisone hydrochloride Chemical Properties,Usage,Production
Chemical Properties
White Solid
Originator
Tolperisone hydrochloride,Shanghai Abochem Chemical Co.
Uses
Tolperisone hydrochloride can be used as a muscle relaxant.
Definition
ChEBI: Tolperisone hydrochloride is an aromatic ketone.
Manufacturing Process
To 1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanol in chloroform was added an excess of thionyl chloride and the reaction mixture refluxed until completed. It was then taken to dryness under reduced pressure and the residue crystallized by dissolving in hot alcohol and diluting with ethyl acetate. An aqueous solution of the obtained N-[3-chloro-3-(p-tolyl)propyl]piperidine hydrochloride was hydrogenated at 3 atmospheres in the presence of buffered palladium-on-charcoal catalyst. 1-Piperidino-2-methyl-3-(p-tolyl)-3-propanone was purified by distilling the base (boiling point 106-107°C/1 mm) and reconverting to the hydrochloride, melting point 216-217°C.
Therapeutic Function
Muscle relaxant, Vasodilator
Biochem/physiol Actions
Tolperisone is derived from piperidine and possesses membrane stabilizing action. It helps in reducing the effect of spasticities associated with the nervous and muscular system. It exhibits muscle relaxant action through attenuating voltage-gated sodium channels in the brain stem.
Tolperisone hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Tolperisone hydrochloride Suppliers
- Tel
- --
- Fax
- --
- contact@fischer-group.ch
- Country
- Switzerland
- ProdList
- 411
- Advantage
- 58
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
View Lastest Price from Tolperisone hydrochloride manufacturers
- Product
- Tolperisone Hydrochloride 3644-61-9
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- More Than 99%
- Supply Ability
- 50kg/Month
- Release date
- 2024-10-09
- Product
- Tolperisone Hydrochloride 3644-61-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-11
- Product
- Tolperisone hydrochloride 3644-61-9
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 20tons
- Release date
- 2024-04-07