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Polyinosinic acid

Product Name
Polyinosinic acid
CAS No.
30918-54-8
Chemical Name
Polyinosinic acid
Synonyms
POLYINOSINIC ACID TRIPOTASSIUM SALT;Poly(rI);Poly(IMP);Inosine acid;Polyinosinic acid;Poly(5’-inosinicacid);POLY RL POTASSIUM SALT;POLY[I] POTASSIUM SALT;Polyinosinic Acid (90%);polyinosinicacidpot.salt
CBNumber
CB7201291
Molecular Formula
C10H13N4O8P
Formula Weight
348.21
MOL File
30918-54-8.mol
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Polyinosinic acid Property

storage temp. 
−20°C
solubility 
Methanol (Slightly), Water (Sparingly)
form 
Solid
color 
White to Off-White
InChI
InChI=1/C10H13N4O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/s3
InChIKey
GRSZFWQUAKGDAV-BFXIWLNFNA-N
SMILES
O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=NC2C(NC=NC1=2)=O)O |&1:1,2,3,11,r|
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Safety

WGK Germany 
3
3-10-21
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P698975
Product name
PolyinosinicAcid(90%)
Packaging
5g
Price
$275
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0000189
Product name
POLYINOSINIC ACID
Purity
95.00%
Packaging
5G
Price
$909.56
Updated
2021/12/16
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Polyinosinic acid Chemical Properties,Usage,Production

Description

Polyinosinic acid Polycytidylic Acid, Sodium Salt, Double-Stranded is a TLR3 (Toll-like receptor 3) agonist. Known to induce interferon production. Hypochromicity: ≥40% at 248 nm. Extinction coefficient = 5000 M-1cm-1 at 260 nm, pH 7.0. Agent for generation of stable, mature dendritic cells (DC) and immunostimulant.

Chemical Properties

White or off-white powder, soluble in water, insoluble in organic solvents such as ethanol and acetaminophen.

Uses

Polyinosinic Acid is an oligolysines used in nucleic acid binding and other biomedical applications.

Application

Polyinosinic acid (Poly(I)) is a homopolymer of inosine that may be used with polycytidylic acid (poly(C)) to form the double-stranded homopolymer (Poly(I).Poly(C)). TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. (Poly(I).Poly(C)) is a used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.

Polyinosinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Polyinosinic acid Suppliers

Hangzhou Weitai Biological Pharmaceutical Co., Ltd.
Tel
86-571-82358004 13588879771
Email
sales1@weitai-pharmaceutical.com
Country
China
ProdList
84
Advantage
58
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Wuhan Wei Shunda Technology Development Co., Ltd.
Tel
86-027-88774375
Fax
86-027-88416321
Email
mwmwhot@163.com
Country
China
ProdList
233
Advantage
65
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8836
Advantage
52
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3295
Advantage
57
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
Nanjing Dulai Biotechnology Co., Ltd.
Tel
025-84699383-8003 18013301590
Fax
025-84699383-8003
Email
njduly@126.com
Country
China
ProdList
971
Advantage
55
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View Lastest Price from Polyinosinic acid manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.
Product
Polyinosinic acid sodium salt,Poly I, POLY I-Na 30918-54-8
Price
US $0.00/kg
Min. Order
1kg
Purity
90.0%Min. HPLC
Supply Ability
1000kg
Release date
2024-09-10
Hangzhou Meiya Pharmaceutical Co Ltd
Product
Polyinosinic acid sodium salt (PI) 30918-54-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
≥90.0%
Supply Ability
10 tons
Release date
2024-02-06
Wuhan Han Sheng New Material Technology Co.,Ltd
Product
POLYINOSINIC ACID (5') POTASSIUM SALT 30918-54-8
Price
US $5.76/KG
Min. Order
10KG
Purity
99%
Supply Ability
100kg
Release date
2023-10-18

30918-54-8, Polyinosinic acidRelated Search:


  • polyinosinicacidpot.salt
  • POLY[I] POTASSIUM SALT
  • POLYINOSINIC ACID (5') POTASSIUM SALT
  • POLYINOSINIC ACID POTASSIUM SALT
  • POLYINOSINIC ACID TRIPOTASSIUM SALT
  • POLY RL POTASSIUM SALT
  • POLYINOSINIC ACID POT. SALT, LYOPH., MR ~1200000
  • 5'-Inosinic acid polymers
  • Polyinosinic acid
  • Polyinosinic acid (Poly I)
  • 5’-Inosinicacid,homopolymer
  • Poly(5’-inosinicacid)
  • Poly(IMP)
  • Poly(rI)
  • [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)-2-oxolanyl]methyl dihydrogen phosphate
  • Polyinosinic Acid (90%)
  • Polyinosinic acid USP/EP/BP
  • Polyinosinic acid sodium salt,Poly I, POLY I-Na
  • Polyinosinic acid sodium
  • Inosine acid
  • Polyinosinic acid sodium salt (PI)
  • 3'-5' cyclic adenosine monophosphate sodium
  • 5'-Inosinic acid polymers
  • 30918-54-8
  • C10H13N4O8Pn
  • BioChemical
  • Biochemicals and Reagents
  • Nucleosides, Nucleotides, Oligonucleotides
  • Synthetic Oligonucleotides and Related Reagents
  • Material
  • Nucleoside Mono