Polyinosinic-polycytidylic acid sodium salt

Product Name: Polyinosinic-polycytidylic acid sodium salt
CAS No.: 42424-50-0
Chemical Name: Polyinosinic-polycytidylic acid sodium salt
Synonyms: Poly (I:C) Na;Poly(I:C) sodium;POLY I POLY C, NA;Polymyocyte sodium salt;POLY[I] POLY[C] SODIUM SALT;polyinosinic-polycytidylic acid sodium;polyI-polyC sodium salt compound solution;POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT;Polyinosinicacid-polycytidylicacidsodiumsal;POLYINOSINIC ACID POLYCYTIDYLIC ACID, SODIUM SALT
CBNumber: CB2187556
Molecular Formula: C19H27N7O16P2
Formula Weight: 671.41
MOL File: 42424-50-0.mol

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Polyinosinic-polycytidylic acid sodium salt Property

storage temp.: −20°C
solubility: H2O: soluble10mg/mL
form: lyophilized powder
color: White to off-white
Water Solubility: Water : 10 mg/mL (Need ultrasonic and warming)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
RTECS: TR0175000

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P0913
Product name: Polyinosinic–polycytidylic acid sodium salt
Purity: ≥99% (less than 1% free nucleotides, TLC)
Packaging: 10mg
Price: $134
Updated: 2024/03/01

Sigma-Aldrich

Product number: P0913
Product name: Polyinosinic–polycytidylic acid sodium salt
Purity: ≥99% (less than 1% free nucleotides, TLC)
Packaging: 50mg
Price: $457
Updated: 2024/03/01

Sigma-Aldrich

Product number: 528906
Product name: Polyinosinic Acid • Polycytidylic Acid, Sodium Salt, Double-Stranded - CAS 42424-50-0 - Calbiochem
Purity: Known to induce interferon production. Hypochromicity: ≥40% at 248 nm. Extinction coefficient = 5000 M-1cm-1 at 260 nm, pH 7.0.
Packaging: 10MG
Price: $115
Updated: 2024/03/01

Sigma-Aldrich

Product number: P1530
Product name: Polyinosinic–polycytidylic acid sodium salt
Purity: TLR ligand tested
Packaging: 25mg
Price: $210
Updated: 2024/03/01

Sigma-Aldrich

Product number: P1530
Product name: Polyinosinic–polycytidylic acid sodium salt
Purity: TLR ligand tested
Packaging: 100mg
Price: $627
Updated: 2024/03/01

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Polyinosinic-polycytidylic acid sodium salt Chemical Properties,Usage,Production

Uses

Polyinosinic Acid & Polycytidylic Acid Sodium Salt (double-stranded) is a TLR3 (Toll-like receptor 3) agonist.

Uses

TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. Polyinosinic–polycytidylic acid sodium salt is a double-stranded homopolymer used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.

Biological Activity

Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis.

storage

Store at -20°C

Polyinosinic-polycytidylic acid sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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Polyinosinic-polycytidylic acid sodium salt Suppliers

China 105 Germany 1 Switzerland 1 United Kingdom 1 United States 10 USA 1 Global 119

HANGZHOU KAIPENG BIOTECHNOLOGY CO., LTD.

Tel: 0571-89939007
Email: kaipengbio@126.com
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ProdList: 10
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Beijing Isomersyn Technology CO;LTD

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Sichuan Kulinan Technology Co., Ltd

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Hubei XinyuanShun Chemical Co., Ltd.

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Shanghai Macklin Biochemical Co.,Ltd.

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Wuhu Nuowei Chemical Technology Co., Ltd

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EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
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View Lastest Price from Polyinosinic-polycytidylic acid sodium salt manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Polyinosinic–polycytidylic acid sodium salt ; Poly (I: C); Poly (I:C) Na; 42424-50-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 90.0%Min. HPLC
Supply Ability: 1000kg
Release date: 2024-09-10

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Polyinosinic-polycytidylic acid sodium salt 42424-50-0
Price: US $0.00/g
Min. Order: 1g
Purity: 45%-55%
Supply Ability: 10kg/month
Release date: 2021-09-28

Career Henan Chemica Co

Product: POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT 42424-50-0
Price: US $1.00/g
Min. Order: 1g
Purity: 85.0-99.8%
Supply Ability: 20 tons
Release date: 2020-11-12

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42424-50-0

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