ChemicalBook > CAS DataBase List > Polyinosinic-polycytidylic acid sodium salt
Polyinosinic-polycytidylic acid sodium salt
- Product Name
- Polyinosinic-polycytidylic acid sodium salt
- CAS No.
- 42424-50-0
- Chemical Name
- Polyinosinic-polycytidylic acid sodium salt
- Synonyms
- Poly (I:C) Na;Poly(I:C) sodium;POLY I POLY C, NA;Polymyocyte sodium salt;POLY[I] POLY[C] SODIUM SALT;polyinosinic-polycytidylic acid sodium;polyI-polyC sodium salt compound solution;POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT;Polyinosinicacid-polycytidylicacidsodiumsal;POLYINOSINIC ACID POLYCYTIDYLIC ACID, SODIUM SALT
- CBNumber
- CB2187556
- Molecular Formula
- C19H27N7O16P2
- Formula Weight
- 671.41
- MOL File
- 42424-50-0.mol
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Polyinosinic-polycytidylic acid sodium salt Property
- storage temp.
- −20°C
- solubility
- H2O: soluble10mg/mL
- form
- lyophilized powder
- color
- White to off-white
- Water Solubility
- Water : 10 mg/mL (Need ultrasonic and warming)
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Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- RTECS
- TR0175000
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- P0913
- Product name
- Polyinosinic–polycytidylic acid sodium salt
- Purity
- ≥99% (less than 1% free nucleotides, TLC)
- Packaging
- 10mg
- Price
- $134
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- P0913
- Product name
- Polyinosinic–polycytidylic acid sodium salt
- Purity
- ≥99% (less than 1% free nucleotides, TLC)
- Packaging
- 50mg
- Price
- $457
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 528906
- Product name
- Polyinosinic Acid • Polycytidylic Acid, Sodium Salt, Double-Stranded - CAS 42424-50-0 - Calbiochem
- Purity
- Known to induce interferon production. Hypochromicity: ≥40% at 248 nm. Extinction coefficient = 5000 M-1cm-1 at 260 nm, pH 7.0.
- Packaging
- 10MG
- Price
- $115
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- P1530
- Product name
- Polyinosinic–polycytidylic acid sodium salt
- Purity
- TLR ligand tested
- Packaging
- 25mg
- Price
- $210
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- P1530
- Product name
- Polyinosinic–polycytidylic acid sodium salt
- Purity
- TLR ligand tested
- Packaging
- 100mg
- Price
- $627
- Updated
- 2024/03/01
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Polyinosinic-polycytidylic acid sodium salt Chemical Properties,Usage,Production
Uses
Polyinosinic Acid & Polycytidylic Acid Sodium Salt (double-stranded) is a TLR3 (Toll-like receptor 3) agonist.
Uses
TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. Polyinosinic–polycytidylic acid sodium salt is a double-stranded homopolymer used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.
Biological Activity
Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis.
storage
Store at -20°C
Polyinosinic-polycytidylic acid sodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Polyinosinic-polycytidylic acid sodium salt manufacturers
HangZhou RunYan Pharma Technology Co.,LTD.
- Product
- Polyinosinic–polycytidylic acid sodium salt ; Poly (I: C); Poly (I:C) Na; 42424-50-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 90.0%Min. HPLC
- Supply Ability
- 1000kg
- Release date
- 2024-09-10
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- Polyinosinic-polycytidylic acid sodium salt 42424-50-0
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 45%-55%
- Supply Ability
- 10kg/month
- Release date
- 2021-09-28
Career Henan Chemica Co
- Product
- POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT 42424-50-0
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 85.0-99.8%
- Supply Ability
- 20 tons
- Release date
- 2020-11-12
42424-50-0, Polyinosinic-polycytidylic acid sodium saltRelated Search:
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