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Polyinosinic acid

Product Name
Polyinosinic acid
CAS No.
30918-54-8
Chemical Name
Polyinosinic acid
Synonyms
POLYINOSINIC ACID TRIPOTASSIUM SALT;Poly(rI);Poly(IMP);Inosine acid;Polyinosinic acid;Poly(5’-inosinicacid);POLY RL POTASSIUM SALT;POLY[I] POTASSIUM SALT;Polyinosinic Acid (90%);polyinosinicacidpot.salt
CBNumber
CB7201291
Molecular Formula
C10H13N4O8P
Formula Weight
348.21
MOL File
30918-54-8.mol
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Polyinosinic acid Property

storage temp. 
−20°C
solubility 
Methanol (Slightly), Water (Sparingly)
form 
Solid
color 
White to Off-White
InChI
InChI=1/C10H13N4O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/s3
InChIKey
GRSZFWQUAKGDAV-BFXIWLNFNA-N
SMILES
O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=NC2C(NC=NC1=2)=O)O |&1:1,2,3,11,r|
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Safety

WGK Germany 
3
F 
3-10-21
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P698975
Product name
PolyinosinicAcid(90%)
Packaging
5g
Price
$275
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0000189
Product name
POLYINOSINIC ACID
Purity
95.00%
Packaging
5G
Price
$909.56
Updated
2021/12/16
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Polyinosinic acid Chemical Properties,Usage,Production

Description

Polyinosinic acid Polycytidylic Acid, Sodium Salt, Double-Stranded is a TLR3 (Toll-like receptor 3) agonist. Known to induce interferon production. Hypochromicity: ≥40% at 248 nm. Extinction coefficient = 5000 M-1cm-1 at 260 nm, pH 7.0. Agent for generation of stable, mature dendritic cells (DC) and immunostimulant.

Chemical Properties

White or off-white powder, soluble in water, insoluble in organic solvents such as ethanol and acetaminophen.

Uses

Polyinosinic Acid is an oligolysines used in nucleic acid binding and other biomedical applications.

Application

Polyinosinic acid (Poly(I)) is a homopolymer of inosine that may be used with polycytidylic acid (poly(C)) to form the double-stranded homopolymer (Poly(I).Poly(C)). TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. (Poly(I).Poly(C)) is a used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.

Polyinosinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Polyinosinic acid manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.
Product
Polyinosinic acid sodium salt，Poly I, POLY I-Na 30918-54-8
Price
US $0.00/kg
Min. Order
1kg
Purity
90.0%Min. HPLC
Supply Ability
1000kg
Release date
2024-09-10
Hangzhou Meiya Pharmaceutical Co Ltd
Product
Polyinosinic acid sodium salt (PI) 30918-54-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
≥90.0%
Supply Ability
10 tons
Release date
2024-02-06
Wuhan Han Sheng New Material Technology Co.，Ltd
Product
POLYINOSINIC ACID (5') POTASSIUM SALT 30918-54-8
Price
US $5.76/KG
Min. Order
10KG
Purity
99%
Supply Ability
100kg
Release date
2023-10-18

30918-54-8, Polyinosinic acidRelated Search:

EPA Poly(L-lysine hydrobromide) Citric acid Folic acid Ethyl 2-(Chlorosulfonyl)acetate Disodium 5'-Inosinate Isoprinosine Stearic acid Ascoric Acid Inosine Polyinosinic-polycytidylic acid sodium salt POLYINOSINIC ACID POLYCYTIDYLIC ACID,POLYINOSINIC ACID . POLYCYTIDYLIC ACID, LYOPHILIZED Inosinic Acid Polyinosinic acid . Polycytidylic acid potassium salt,polyinosinic acid/ polycytidylic potassium POLYINOSINIC ACID (5') POTASSIUM SALT Polyinosinic acid 5'-POLYINOSINIC ACID DISODIUM SALT = 5'-POLYI-NA2 POLYMERS

  • polyinosinicacidpot.salt
  • POLY[I] POTASSIUM SALT
  • POLYINOSINIC ACID (5') POTASSIUM SALT
  • POLYINOSINIC ACID POTASSIUM SALT
  • POLYINOSINIC ACID TRIPOTASSIUM SALT
  • POLY RL POTASSIUM SALT
  • POLYINOSINIC ACID POT. SALT, LYOPH., MR ~1200000
  • 5'-Inosinic acid polymers
  • Polyinosinic acid
  • Polyinosinic acid (Poly I)
  • 5’-Inosinicacid,homopolymer
  • Poly(5’-inosinicacid)
  • Poly(IMP)
  • Poly(rI)
  • [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)-2-oxolanyl]methyl dihydrogen phosphate
  • Polyinosinic Acid (90%)
  • Polyinosinic acid USP/EP/BP
  • Polyinosinic acid sodium salt，Poly I, POLY I-Na
  • Polyinosinic acid sodium
  • Inosine acid
  • Polyinosinic acid sodium salt (PI)
  • 3'-5' cyclic adenosine monophosphate sodium
  • 5'-Inosinic acid polymers
  • 30918-54-8
  • C10H13N4O8Pn
  • BioChemical
  • Biochemicals and Reagents
  • Nucleosides, Nucleotides, Oligonucleotides
  • Synthetic Oligonucleotides and Related Reagents
  • Material
  • Nucleoside Mono