Polyinosinic acid

ChemicalBook > CAS DataBase List > Polyinosinic acid

Product Name: Polyinosinic acid
CAS No.: 30918-54-8
Chemical Name: Polyinosinic acid
Synonyms: POLYINOSINIC ACID TRIPOTASSIUM SALT;Poly(rI);Poly(IMP);Inosine acid;Polyinosinic acid;Poly(5’-inosinicacid);POLY RL POTASSIUM SALT;POLY[I] POTASSIUM SALT;Polyinosinic Acid (90%);polyinosinicacidpot.salt
CBNumber: CB7201291
Molecular Formula: C10H13N4O8P
Formula Weight: 348.21
MOL File: 30918-54-8.mol

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Polyinosinic acid Property

storage temp.: −20°C
solubility: Methanol (Slightly), Water (Sparingly)
form: Solid
color: White to Off-White
InChI: InChI=1/C10H13N4O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/s3
InChIKey: GRSZFWQUAKGDAV-BFXIWLNFNA-N
SMILES: O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=NC2C(NC=NC1=2)=O)O |&1:1,2,3,11,r|

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Safety

WGK Germany: 3
F: 3-10-21

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: P698975
Product name: PolyinosinicAcid(90%)
Packaging: 5g
Price: $275
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PXT0000189
Product name: POLYINOSINIC ACID
Purity: 95.00%
Packaging: 5G
Price: $909.56
Updated: 2021/12/16

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Polyinosinic acid Chemical Properties,Usage,Production

Description

Polyinosinic acid Polycytidylic Acid, Sodium Salt, Double-Stranded is a TLR3 (Toll-like receptor 3) agonist. Known to induce interferon production. Hypochromicity: ≥40% at 248 nm. Extinction coefficient = 5000 M-1cm-1 at 260 nm, pH 7.0. Agent for generation of stable, mature dendritic cells (DC) and immunostimulant.

Chemical Properties

White or off-white powder, soluble in water, insoluble in organic solvents such as ethanol and acetaminophen.

Uses

Polyinosinic Acid is an oligolysines used in nucleic acid binding and other biomedical applications.

Application

Polyinosinic acid (Poly(I)) is a homopolymer of inosine that may be used with polycytidylic acid (poly(C)) to form the double-stranded homopolymer (Poly(I).Poly(C)). TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. (Poly(I).Poly(C)) is a used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.

Polyinosinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Polyinosinic acid manufacturers

Hangzhou Meiya Pharmaceutical Co Ltd

Product: Polyinosinic acid sodium salt (PI) 30918-54-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: ≥90.0%
Supply Ability: 10 tons
Release date: 2024-02-06

Wuhan Han Sheng New Material Technology Co.，Ltd

Product: POLYINOSINIC ACID (5') POTASSIUM SALT 30918-54-8
Price: US $5.76/KG
Min. Order: 10KG
Purity: 99%
Supply Ability: 100kg
Release date: 2023-10-18

Wuhan Han Sheng New Material Technology Co.，Ltd

Product: POLYINOSINIC ACID POTASSIUM SALT 30918-54-8
Price: US $5.75/KG
Min. Order: 10KG
Purity: 99%
Supply Ability: 100kg
Release date: 2023-10-17

30918-54-8, Polyinosinic acidRelated Search:

EPA Poly(L-lysine hydrobromide) Citric acid Folic acid Ethyl 2-(Chlorosulfonyl)acetate Disodium 5'-Inosinate Isoprinosine Stearic acid Ascoric Acid Inosine Polyinosinic-polycytidylic acid sodium salt POLYINOSINIC ACID POLYCYTIDYLIC ACID,POLYINOSINIC ACID . POLYCYTIDYLIC ACID, LYOPHILIZED Inosinic Acid Polyinosinic acid . Polycytidylic acid potassium salt,polyinosinic acid/ polycytidylic potassium POLYINOSINIC ACID (5') POTASSIUM SALT Polyinosinic acid 5'-POLYINOSINIC ACID DISODIUM SALT = 5'-POLYI-NA2 POLYMERS

polyinosinicacidpot.salt

POLY[I] POTASSIUM SALT

POLYINOSINIC ACID (5') POTASSIUM SALT

POLYINOSINIC ACID POTASSIUM SALT

POLYINOSINIC ACID TRIPOTASSIUM SALT

POLY RL POTASSIUM SALT

POLYINOSINIC ACID POT. SALT, LYOPH., MR ~1200000

5'-Inosinic acid polymers

Polyinosinic acid

Polyinosinic acid (Poly I)

5’-Inosinicacid,homopolymer

Poly(5’-inosinicacid)

Poly(IMP)

Poly(rI)

[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)-2-oxolanyl]methyl dihydrogen phosphate

Polyinosinic Acid (90%)

Polyinosinic acid USP/EP/BP

Polyinosinic acid sodium salt，Poly I, POLY I-Na

Polyinosinic acid sodium

Inosine acid

Polyinosinic acid sodium salt (PI)

30918-54-8

C10H13N4O8Pn

BioChemical

Biochemicals and Reagents

Nucleosides, Nucleotides, Oligonucleotides

Synthetic Oligonucleotides and Related Reagents

Material