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ALPHA-GUANIDINOGLUTARIC ACID

Product Name
ALPHA-GUANIDINOGLUTARIC ACID
CAS No.
73477-53-9
Chemical Name
ALPHA-GUANIDINOGLUTARIC ACID
Synonyms
GGA;Guanidinoglutaricacid;alpha-Guanidinoglutaric;A-GUANIDINOGLUTARIC ACID;α-Guanidinoglutaric acid;2-Guanidinopentanedioic acid;ALPHA-GUANIDINOGLUTARIC ACID;(S)-(-)-2-GUANIDINOGLUTARIC ACID;(S)-(-)-2-GuanidinoglutaricAcid>N-(AMINOIMINOMETHYL)-L-GLUTAMIC ACID
CBNumber
CB7214785
Molecular Formula
C6H11N3O4
Formula Weight
189.17
MOL File
73477-53-9.mol
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ALPHA-GUANIDINOGLUTARIC ACID Property

Boiling point:
414.7±55.0 °C(Predicted)
Density 
1.62±0.1 g/cm3(Predicted)
refractive index 
-20 ° (C=4, 2mol/L HCl)
storage temp. 
2-8°C
solubility 
PBS pH 7.2: >50 mg/ml
form 
White crystalline solid.
pka
3.28±0.10(Predicted)
color 
White to Almost white
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Safety

HS Code 
2925.29.6000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
G0265
Product name
(S)-(-)-2-Guanidinoglutaric Acid
Purity
>98.0%(T)
Packaging
100mg
Price
$99
Updated
2023/06/20
Cayman Chemical
Product number
80340
Product name
α-Guanidinoglutaric Acid
Purity
≥98%
Packaging
5mg
Price
$28
Updated
2024/03/01
Cayman Chemical
Product number
80340
Product name
α-Guanidinoglutaric Acid
Purity
≥98%
Packaging
10mg
Price
$50
Updated
2024/03/01
Cayman Chemical
Product number
80340
Product name
α-Guanidinoglutaric Acid
Purity
≥98%
Packaging
50mg
Price
$207
Updated
2024/03/01
Cayman Chemical
Product number
80340
Product name
α-Guanidinoglutaric Acid
Purity
≥98%
Packaging
100mg
Price
$357
Updated
2024/03/01
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ALPHA-GUANIDINOGLUTARIC ACID Chemical Properties,Usage,Production

Description

GGA is a linear mixed-type inhibitor of nNOS having a Ki of 2.69 μM. It is normally present in small quantities in the cerebral cortex of cats with increased levels following seizure.

Uses

α-Guanidinoglutaric acid is a guanidino compound first found in cobaltinduced epileptogenic focus tissue in the cerebral cortex of cats. α-Guanidinoglutaric acid induces epileptic seizures in rats after intraventricular administration[1].

Definition

ChEBI: N-Amidino-L-glutamate is a L-glutamic acid derivative.

References

[1] H Shiraga, et al. Convulsive activity of alpha-guanidinoglutaric acid and the possible involvement of 5-hydroxytryptamine in the alpha-guanidinoglutaric acid-induced seizure mechanism. J Neurochem. 1986 Dec;47(6):1832-6. DOI:10.1111/j.1471-4159.1986.tb13095.x

ALPHA-GUANIDINOGLUTARIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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73477-53-9, ALPHA-GUANIDINOGLUTARIC ACIDRelated Search:

Mifepristone ALPHA-GUANIDINOGLUTARIC ACID (S)-(-)-2-GUANIDINOGLUTARIC ACID S-METHYLISOTHIOUREA SALT α-guaiene,guaia-1(5),11-diene,[1S-(1a,4a,7a)]-1,2,3,4,5,6,7,8-octahydro-1,4-dimethyl-7-(1-methylethenyl)-azulene 3,5-Pyridinedicarboxylic acid, 4-(1,3-benzodioxol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester 2H-Benzimidazole-2-thione, 5-[[(2,4-dihydroxyphenyl)methylene]amino]-1,3-dihydro- 2-Propenoic acid, 3-(4-methylphenyl)-, 2-oxo-2H-1-benzopyran-4-yl ester, (2E)- α-Glucosidase-IN-29 KRN7000 α-galactosidase 5H-Indeno[1,2-b]pyridin-5-one, 6,7-dimethoxy-4-methyl- Benzoic acid, 4-[2-[(Z)-(4,5-dihydro-6-methyl-3,4-dioxofuro[3,4-c]pyridin-1(3H)-ylidene)methyl]-5-(hydroxymethyl)-1H-pyrrol-1-yl]-, ethyl ester 3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)- Benzenesulfonamide, N-[4-[5-(4-chlorophenyl)-1-oxo-2,4-pentadien-1-yl]phenyl]-4-(trifluoromethyl)- 3,5-Pyridinedicarbonitrile, 2-amino-4-(4-bromo-3,5-dimethoxyphenyl)-6-(phenylthio)-

  • GGA
  • ALPHA-GUANIDINOGLUTARIC ACID
  • Guanidinoglutaricacid
  • A-GUANIDINOGLUTARIC ACID
  • (S)-(-)-2-GUANIDINOGLUTARIC ACID 98+%
  • alpha-Guanidinoglutaric
  • 2-Guanidinopentanedioic acid
  • (<i>S</i>)-(-)-2-Guanidinoglutaric Acid
  • (S)-(-)-2-GUANIDINOGLUTARIC ACID
  • N-(AMINOIMINOMETHYL)-L-GLUTAMIC ACID
  • (S)-(-)-2-GuanidinoglutaricAcid&gt
  • α-Guanidinoglutaric acid
  • (2S)-2-(Diaminomethylideneamino)pentanedioic Acid
  • αGuanidinoglutaric Acid,α Guanidinoglutaric Acid
  • L-Glutamic acid, N-(aminoiminomethyl)-
  • α-Guanidinoglutaric Acid, 10 mM in DMSO
  • 73477-53-9
  • C6H11N3O4
  • BioChemical
  • Biochemicals and Reagents
  • Nitric Oxide Synthase
  • Enzyme Inhibitors
  • Enzyme Inhibitors by Enzyme
  • Enzymes, Inhibitors, and Substrates
  • L to O
  • amino acids