ChemicalBook > CAS DataBase List > 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde

Product Name
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
CAS No.
27006-76-4
Chemical Name
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
Synonyms
BUTTPARK 36\18-27;TIMTEC-BB SBB005568;5-Chloro-1,3-Dimethyl-1H-Pyraz;5-Chloro-1,3-dimethyl-1H-pyrazole-4-;5-Chloro-4-formyl-1,3-dimethylpyrazole;5-CHLORO-1,3-DIMETHYL PYRAZOLE-4-ALDEHYDE;5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-ALDEHYDE;5-chloro-1,3-dimethylpyrazole-4-carbaldehyde;5-Chloro-1,3-dimethyl-4-pyrazolecarbaldehyde;5-CHLORO-1,3-DIMETHYLPYRAZOLE-4-CARBOXALDEHYDE
CBNumber
CB7224182
Molecular Formula
C6H7ClN2O
Formula Weight
158.59
MOL File
27006-76-4.mol
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5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Property

Melting point:
78-79°C
Boiling point:
255.7±35.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder to crystal
pka
-0.60±0.10(Predicted)
color 
White to Yellow to Orange
CAS DataBase Reference
27006-76-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-37/39-36/37/39-22
RIDADR 
2811
HazardClass 
IRRITANT
HS Code 
29124990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C2747
Product name
5-Chloro-1,3-dimethylpyrazole-4-carboxaldehyde
Purity
>98.0%(GC)
Packaging
1g
Price
$85
Updated
2025/07/31
TCI Chemical
Product number
C2747
Product name
5-Chloro-1,3-dimethylpyrazole-4-carboxaldehyde
Purity
>98.0%(GC)
Packaging
5g
Price
$291
Updated
2025/07/31
TRC
Product number
C584783
Product name
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
Packaging
50mg
Price
$60
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK118057
Product name
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
Purity
97%
Packaging
1g
Price
$83
Updated
2021/12/16
Matrix Scientific
Product number
042926
Product name
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
Purity
>95%
Packaging
25g
Price
$140
Updated
2021/12/16
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5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Chemical Properties,Usage,Production

Chemical Properties

Off-white to brown solid

Synthesis

3201-29-4

68-12-2

27006-76-4

Step 2: Synthesis of 5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde: 2,5-dimethyl-1H-pyrazol-3(2H)-one (32 g, 285.71 mmol) was mixed with POCl3 (128 mL) at 0 °C and N,N-dimethylformamide (26.35 mL, 342.85 mmol) was added slowly. The reaction mixture was warmed to 100 °C and stirred for 7 h, during which the progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was concentrated to dryness under reduced pressure. The residue was alkalized with aqueous sodium bicarbonate and extracted with ethyl acetate. The organic layers were combined, dried with anhydrous Na2SO4 and concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography to afford the target compound 5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde (28 g, 62.0% yield).

References

[1] Patent: WO2015/10049, 2015, A1. Location in patent: Paragraph 0712; 0713
[2] Patent: WO2015/200650, 2015, A1. Location in patent: Paragraph 0519; 0522-0523
[3] Patent: CN103951663, 2016, B. Location in patent: Paragraph 0221; 0224; 0225

5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Preparation Products And Raw materials

Raw materials

Ethyl acetoacetate N,N-Dimethylformamide Phosphorus oxitrichloride 1,3-Dimethyl-5-pyrazolone Methylhydrazine

Preparation Products

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5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Suppliers

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View Lastest Price from 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 27006-76-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 27006-76-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 27006-76-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-26

27006-76-4, 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehydeRelated Search:

Pyrazole Dimethyl fumarate Dimethyl ether N,N-Dimethylformamide Dimethyl sulfoxide Pyraclostrobin 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one Dimethyl sulfide Zolpidem tartrate Dimethyl phthalate ETHANE Zolpidem 5-CHLORO-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXALDEHYDE 5-CHLORO-1,3-DIMETHYLPYRAZOLE 1H-Pyrazole-4-carboxaldehyde 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde

  • 5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBALDEHYDE
  • 5-CHLORO-1,3-DIMETHYL PYRAZOLE-4-ALDEHYDE
  • 5-CHLORO-1,3-DIMETHYLPYRAZOLE-4-CARBOXALDEHYDE
  • 5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXALDEHYDE
  • BUTTPARK 36\18-27
  • TIMTEC-BB SBB005568
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  • 5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-ALDEHYDE
  • 1，3-dimethyl-5-chloro-1 H-pyrazole-4-carboxaldehyde
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  • 1,3-Dimethyl-5-chloro-1H-pyrazole-4-carbaldehyde
  • 5-Chloro-1,3-diMethyl-4-pyrazolecarboxaldehyde
  • 5-chloro-1,3-dimethylpyrazole-4-carbaldehyde
  • 5-Chloro-1,3-dimethyl-1H-pyrazole-4-
  • 5-Chloro-1,3-dimethylpyrazole-4-carboxaldehyde&gt
  • 5-Chloro-1,3-dimethyl-4-pyrazolecarbaldehyde
  • 1H-Pyrazole-4-carboxaldehyde, 5-chloro-1,3-dimethyl-
  • 5-Chloro-4-formyl-1,3-dimethylpyrazole
  • 5-Chloro-1,3-dimethyl-1H-pyrazol-4-carbaldehyde
  • 5-chloro-1, 3-dimethyl-1h-pyrazol-4-formaldehyde
  • 27006-76-4
  • ALDEHYDE
  • Pyrazoles & Triazoles
  • Aldehydes
  • Pyrazoles & Triazoles