5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
- Product Name
- 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
- CAS No.
- 27006-76-4
- Chemical Name
- 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
- Synonyms
- BUTTPARK 36\18-27;TIMTEC-BB SBB005568;5-Chloro-1,3-Dimethyl-1H-Pyraz;5-Chloro-1,3-dimethyl-1H-pyrazole-4-;5-Chloro-4-formyl-1,3-dimethylpyrazole;5-CHLORO-1,3-DIMETHYL PYRAZOLE-4-ALDEHYDE;5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-ALDEHYDE;5-chloro-1,3-dimethylpyrazole-4-carbaldehyde;5-Chloro-1,3-dimethyl-4-pyrazolecarbaldehyde;5-CHLORO-1,3-DIMETHYLPYRAZOLE-4-CARBOXALDEHYDE
- CBNumber
- CB7224182
- Molecular Formula
- C6H7ClN2O
- Formula Weight
- 158.59
- MOL File
- 27006-76-4.mol
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Property
- Melting point:
- 78-79°C
- Boiling point:
- 255.7±35.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- powder to crystal
- pka
- -0.60±0.10(Predicted)
- color
- White to Yellow to Orange
- CAS DataBase Reference
- 27006-76-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-37/39-36/37/39-22
- RIDADR
- 2811
- HazardClass
- IRRITANT
- HS Code
- 29124990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C2747
- Product name
- 5-Chloro-1,3-dimethylpyrazole-4-carboxaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $85
- Updated
- 2025/07/31
- Product number
- C2747
- Product name
- 5-Chloro-1,3-dimethylpyrazole-4-carboxaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $291
- Updated
- 2025/07/31
- Product number
- C584783
- Product name
- 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- S832
- Product name
- 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
- Packaging
- 1g
- Price
- $14
- Updated
- 2021/12/16
- Product number
- 042926
- Product name
- 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde
- Purity
- >95%
- Packaging
- 1g
- Price
- $14
- Updated
- 2021/12/16
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Chemical Properties,Usage,Production
Chemical Properties
Off-white to brown solid
Synthesis
3201-29-4
68-12-2
27006-76-4
Step 2: Synthesis of 5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde: 2,5-dimethyl-1H-pyrazol-3(2H)-one (32 g, 285.71 mmol) was mixed with POCl3 (128 mL) at 0 °C and N,N-dimethylformamide (26.35 mL, 342.85 mmol) was added slowly. The reaction mixture was warmed to 100 °C and stirred for 7 h, during which the progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was concentrated to dryness under reduced pressure. The residue was alkalized with aqueous sodium bicarbonate and extracted with ethyl acetate. The organic layers were combined, dried with anhydrous Na2SO4 and concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography to afford the target compound 5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde (28 g, 62.0% yield).
References
[1] Patent: WO2015/10049, 2015, A1. Location in patent: Paragraph 0712; 0713
[2] Patent: WO2015/200650, 2015, A1. Location in patent: Paragraph 0519; 0522-0523
[3] Patent: CN103951663, 2016, B. Location in patent: Paragraph 0221; 0224; 0225
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde Suppliers
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View Lastest Price from 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde manufacturers
- Product
- 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 27006-76-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 27006-76-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde 27006-76-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-26