Cyclobutanone
Description References- Product Name
- Cyclobutanone
- CAS No.
- 1191-95-3
- Chemical Name
- Cyclobutanone
- Synonyms
- CBON;obutanone;CYCLOBUTANONE;Oxocyclobutane;1-Oxocyclobutane;Cyclobutanone 98%;Cyclobutanone, 98+%;OS-7558Cyclobutanone;cyclobutanone(SALTDATA: FREE);Cyclobutanone, 98%, stabilized
- CBNumber
- CB7231982
- Molecular Formula
- C4H6O
- Formula Weight
- 70.09
- MOL File
- 1191-95-3.mol
Cyclobutanone Property
- Melting point:
- -50.9 °C
- Boiling point:
- 99 °C (lit.)
- Density
- 0.938 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.421(lit.)
- Flash point:
- 50 °F
- storage temp.
- 2-8°C
- solubility
- soluble in Dichloromethane
- form
- Liquid
- Specific Gravity
- 0.938
- color
- Clear colorless to slightly yellow
- Water Solubility
- INSOLUBLE
- BRN
- 1560289
- Stability:
- Volatile
- InChIKey
- SHQSVMDWKBRBGB-UHFFFAOYSA-N
- CAS DataBase Reference
- 1191-95-3(CAS DataBase Reference)
- EPA Substance Registry System
- Cyclobutanone (1191-95-3)
Safety
- Hazard Codes
- F,F+
- Risk Statements
- 10-11
- Safety Statements
- 23-24/25-9-33-29-16-7/9
- RIDADR
- UN 1224 3/PG 3
- WGK Germany
- 3
- TSCA
- Yes
- HazardClass
- 3
- PackingGroup
- II
- HS Code
- 29142900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
N-Bromosuccinimide Price
- Product number
- C96001
- Product name
- Cyclobutanone
- Purity
- 99%
- Packaging
- 1g
- Price
- $33.4
- Updated
- 2024/03/01
- Product number
- C96001
- Product name
- Cyclobutanone
- Purity
- 99%
- Packaging
- 5g
- Price
- $159
- Updated
- 2024/03/01
- Product number
- C1913
- Product name
- Cyclobutanone (stabilized with Na2CO3)
- Purity
- >97.0%(GC)
- Packaging
- 1g
- Price
- $55
- Updated
- 2024/03/01
- Product number
- C1913
- Product name
- Cyclobutanone (stabilized with Na2CO3)
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $180
- Updated
- 2024/03/01
- Product number
- A13068
- Product name
- Cyclobutanone, 98%, stab. with ca 0.01% BHT
- Packaging
- 1g
- Price
- $74.65
- Updated
- 2024/03/01
Cyclobutanone Chemical Properties,Usage,Production
Description
Cyclobutanone is an organic compound with a four-membered cyclic ketone. It is used in preparation of cyclobutane derivatives, as a starting material for aminocyclobutanecarboxylic acid through sulfonyloxiranes, to prepare dihydro-furan-2-one in presence of polystyrene-bound phenylselenic acid as catalyst. It is also involved in the photochemical synthesis of nucleoside analogues such as bicyclic nucleosides and isonucleosides. Furthermore, it is used to synthesis fatty acid, 2-oxo-cyclobutane undecanoic acid, which is used in the development of an enzyme-linked immunosorbent assy for the detection of irradiated foods.
References
[1] https://en.wikipedia.org/wiki/Cyclobutanone
[2] https://www.alfa.com/de/catalog/A13068/
[3] https://www.scbt.com/scbt/de/product/2-oxo-cyclobutane-undecanoic-acid-169263-77-8/;jsessionid=Ay2KMCxORq9y-EC6YoYnGGtCnymUGxQi5Lpd-YuCZoW22Re8Xf4w!-2072765631
Chemical Properties
Clear colourless to slightly yellow liquid
Uses
Cyclobutanone is used in preparation of cyclobutane derivatives. It is used as a starting material for aminocyclobutanecarboxylic acid through sulfonyloxiranes. It is also used to prepare dihydro-furan-2-one in presence of polystyrene-bound phenylselenic acid as catalyst. Further, it is involved in the photochemical synthesis of nucleoside analogues such as bicyclic nucleosides and isonucleosides.
Preparation
The Russian chemist Nikolai Kischner first prepared cyclobutanone in 1905. He synthesized cyclobutanone in a low yield from cyclobutanecarboxylic acid in several reaction steps.
Another synthesis of cyclobutanone involves lithium-catalyzed rearrangement of oxaspiropentane, which is formed by epoxidation of the easily accessible methylenecyclopropane.
Purification Methods
Treat cyclobutanone with dilute aqueous KMnO4, dry it with molecular sieves and fractionally distil it. Purify it via the semicarbazone, then regenerate the ketone, dry it (CaSO4), and distil it in a stainless steel spinning-band (or Vigreux, p 11) column. Alternatively, purify it by preparative gas chromatography using a Carbowax 20-M column at 80o. (This treatment also removes acetone). The oxime has m 84-85o (from pet ether) and the semicarbazone has m 212-212-5o (220-221o from MeOH or H2O, Buchanan et al. J Am Chem Soc 64 2701 1942). [Salaun Org Synth 57 36 1977, Fitzer & Quabeck Synthesis 299 1987, Beilstein 7 IV 3.]
Cyclobutanone Preparation Products And Raw materials
Raw materials
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View Lastest Price from Cyclobutanone manufacturers
- Product
- Cyclobutanone 1191-95-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.10000000149011612kg
- Purity
- 99.0%min
- Supply Ability
- 200kg
- Release date
- 2023-07-03
- Product
- Cyclobutanone 1191-95-3
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2023-05-11
- Product
- Cyclobutanone 1191-95-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10