alpha,alpha'-Dibromo-p-xylene

Product Name: alpha,alpha'-Dibromo-p-xylene
CAS No.: 623-24-5
Chemical Name: alpha,alpha'-Dibromo-p-xylene
Synonyms: 1,4-BIS(BROMOMETHYL)BENZENE;P-XYLYLENE DIBROMIDE;α,α′-Dibromo-p-xylene;P-XYLENE DIBROMIDE;1,4-bis(bromomethyl)-benzen;NSC 6226;O-dibroMo-benzyl;AKOS BBS-00000840;P-XYLYLENE BROMIDE;α,α'-Dibromo-p-xyL
CBNumber: CB7235218
Molecular Formula: C8H8Br2
Formula Weight: 263.96
MOL File: 623-24-5.mol

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alpha,alpha'-Dibromo-p-xylene Property

Melting point:: 143-145 °C(lit.)
Boiling point:: 245 °C(lit.)
Density: 2.012
refractive index: 1.614
Flash point:: 155-158°C/14mm
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: dioxane: soluble1g/10 mL (hot)
form: Crystalline Powder and Coarse Crystals
color: White to beige
Water Solubility: soluble, hydrolyses
Sensitive: Lachrymatory
BRN: 1100019
CAS DataBase Reference: 623-24-5(CAS DataBase Reference)
NIST Chemistry Reference: Benzene, 1,4-bis(bromomethyl)-(623-24-5)
EPA Substance Registry System: 1,4-Bis(bromomethyl)benzene (623-24-5)

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Safety

Hazard Codes: C
Risk Statements: 34-22
Safety Statements: 26-36/37/39-45
RIDADR: UN 3448 6.1/PG 2
WGK Germany: 3
F: 8-19-21
Hazard Note: Corrosive/Lachrymatory
TSCA: Yes
HazardClass: 8
PackingGroup: III
HS Code: 29039990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 34440
Product name: α,α′-Dibromo-p-xylene
Purity: purum, ≥98.0% (GC)
Packaging: 25g
Price: $120
Updated: 2025/07/31

Sigma-Aldrich

Product number: 34440
Product name: α,α′-Dibromo-p-xylene
Purity: purum, ≥98.0% (GC)
Packaging: 100g
Price: $337
Updated: 2025/07/31

TCI Chemical

Product number: D0216
Product name: α,α'-Dibromo-p-xylene
Packaging: 25G
Price: $97
Updated: 2025/07/31

Sigma-Aldrich

Product number: D44804
Product name: α,α′-Dibromo-p-xylene
Purity: 97%
Packaging: 5g
Price: $57.9
Updated: 2025/07/31

Sigma-Aldrich

Product number: D44804
Product name: α,α′-Dibromo-p-xylene
Purity: 97%
Packaging: 25g
Price: $130
Updated: 2025/07/31

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alpha,alpha'-Dibromo-p-xylene Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals.

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 7055, 1994 DOI: 10.1016/0040-4039(94)88224-X

Synthesis

106-42-3

623-24-5

2.3.2.1 Synthesis of 1,4-bis(bromomethyl)benzene 4 In a 250 mL round bottom flask, p-xylene 1 (5 mL, 40.78 mmol) and 70 mL carbon tetrachloride were added as solvents. The flask was heated in an oil bath. Subsequently, N-bromosuccinimide (29.86 g, 167.80 mmol) and benzoyl peroxide (5.83 g, 24.08 mmol) were added sequentially to the flask. The reaction mixture was refluxed at 70 °C for 12 hours. Upon completion of the reaction, the solution was cooled to room temperature, at which point a solid imide precipitated, which was removed by filtration. The filtrate was distilled under reduced pressure to remove the solvent to give the light yellow solid product 1,4-bis(bromomethyl)benzene 4 in 90% yield with a melting point of 142-144 °C. The product was analyzed by FT-IR (KBr, cm^-1) showing 568 (C-Br stretching vibration), 1625 (C=C stretching vibration); 1H NMR (300 MHz, CDCl3) showing 4.28 (s, 4H, methylene proton), 7.18 (s, 4H, aromatic proton).

Purification Methods

Distil it under a vacuum and recrystallise it from EtOH, *benzene or chloroform. [Wenner Org Chem 17 527 1952, Beilstein 5 H 385, 5 I 187, 5 II 301, 5 III 859, 5 IV 970.]

References

[1] Tetrahedron Letters, 2000, vol. 41, # 32, p. 6241 - 6244
[2] Tetrahedron Letters, 2005, vol. 46, # 41, p. 7047 - 7050
[3] Synthetic Communications, 2009, vol. 39, # 13, p. 2304 - 2309
[4] Journal of Molecular Catalysis A: Chemical, 2012, vol. 363-364, p. 81 - 89,9
[5] Polyhedron, 2012, vol. 47, # 1, p. 151 - 164

alpha,alpha'-Dibromo-p-xylene Preparation Products And Raw materials

Raw materials

Benzoyl peroxide P-XYLENE N-Bromosuccinimide 1,4-Benzenedimethanol Carbon tetrachloride Dichloromethane Phosphorus tribromide

Preparation Products

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alpha,alpha'-Dibromo-p-xylene Suppliers

Americas 1 Belgium 1 Canada 2 China 281 Europe 3 Germany 5 India 20 Japan 4 Slovakia 1 South Korea 1 Switzerland 3 United Kingdom 19 United States 32 Global 373

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View Lastest Price from alpha,alpha'-Dibromo-p-xylene manufacturers

R&D Scientific Inc.

Product: p-Xylylene dibromide 623-24-5
Price: US $2200.00/Kg
Min. Order: 1Kg
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-05-07

Henan Fengda Chemical Co., Ltd

Product: alpha,alpha'-Dibromo-p-xylene 623-24-5
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-25

Honest Joy Holdings Limited

Product: P-Xylylene dibromide 623-24-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.6%
Supply Ability: 100 tons
Release date: 2022-02-21

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