N-Boc-1,3-propanediamine

Product Name: N-Boc-1,3-propanediamine
CAS No.: 75178-96-0
Chemical Name: N-Boc-1,3-propanediamine
Synonyms: Boc-DAP;tert-butyl 3-aminopropylcarbamate;(3-AMINO-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER;N-BOC-1,3-DIAMINOPROPANE;TERT-BUTYL N-(3-AMINOPROPYL)CARBAMATE;N-Boc-1,3-propanediaMine (N-Boc-1,3-diaMinopropane;G1-12;AURORA KA-4396;BUTTPARK 27\08-80;T BOC PROPANAMINE
CBNumber: CB7242775
Molecular Formula: C8H18N2O2
Formula Weight: 174.24
MOL File: 75178-96-0.mol

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N-Boc-1,3-propanediamine Property

Melting point:: 22 °C (lit.)
Boiling point:: 203 °C (lit.)
Density: 0.998 g/mL at 20 °C (lit.)
refractive index: n20/D 1.454(lit.)
Flash point:: >230 °F
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Miscible with methanol.
pka: 12.73±0.46(Predicted)
form: Liquid
Specific Gravity: 0.998
color: Colorless
Sensitive: Air Sensitive
BRN: 3588328
InChIKey: POHWAQLZBIMPRN-UHFFFAOYSA-N
CAS DataBase Reference: 75178-96-0(CAS DataBase Reference)

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Safety

Hazard Codes: C
Risk Statements: 22-34
Safety Statements: 26-36/37/39-45
RIDADR: UN 3259 8/PG 3
WGK Germany: 3
F: 10-34
Hazard Note: Irritant
HazardClass: 8
PackingGroup: III
HS Code: 29212900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 15408
Product name: N-Boc-1,3-propanediamine
Purity: ≥97.0% (GC/NT)
Packaging: 1ml
Price: $281
Updated: 2025/07/31

Sigma-Aldrich

Product number: 15408
Product name: N-Boc-1,3-propanediamine
Purity: ≥97.0% (GC/NT)
Packaging: 5ml
Price: $442
Updated: 2025/07/31

TCI Chemical

Product number: A1372
Product name: N-(tert-Butoxycarbonyl)-1,3-diaminopropane
Purity: >98.0%(GC)
Packaging: 1g
Price: $76
Updated: 2025/07/31

TCI Chemical

Product number: A1372
Product name: N-(tert-Butoxycarbonyl)-1,3-diaminopropane
Purity: >98.0%(GC)
Packaging: 5g
Price: $241
Updated: 2025/07/31

Usbiological

Product number: 266941
Product name: N-Boc-1,3-diaminopropane
Packaging: 5g
Price: $340
Updated: 2021/12/16

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N-Boc-1,3-propanediamine Chemical Properties,Usage,Production

Chemical Properties

Colorless to light yellow liquid

Uses

N-Boc-1,3-diaminopropane is used in the preparation of spermidine analogues as well as in the preparation of pharmacologically active compounds. It is also used in suzuki reaction. Further, it is used in the preparation of [3-(3-cyano-propylamino)-propyl]-carbamic acid tert-butyl ester.

reaction suitability

reagent type: cross-linking reagent
reagent type: spacer

Synthesis

24424-99-5

109-76-2

75178-96-0

GENERAL PROCEDURE: To a suspension of 1,3-propanediamine (20.0 g, 172 mmol) in 50 mL of dichloromethane (DCM) cooled to 0°C, a solution of di-tert-butyl dicarbonate (Boc2O, 3.75 g, 17.2 mmol) in 24 mL of DCM was slowly added. After addition, the ice bath was removed and the reaction mixture was stirred at room temperature for 18 hours. After completion of the reaction, the precipitate was removed by filtration and the filtrate was washed sequentially with saturated aqueous sodium bicarbonate (NaHCO3) (3 x 50 mL), water (2 x 50 mL) and brine (50 mL). The organic layer was dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to give an oily product N-tert-butoxycarbonyl-1,3-propanediamine 3.1 g in 84% yield.

References

[1] Journal of Organic Chemistry, 1997, vol. 62, # 2, p. 411 - 416
[2] Liebigs Annales, 1996, # 6, p. 935 - 939
[3] Bioorganic and Medicinal Chemistry, 2002, vol. 10, # 4, p. 1009 - 1018
[4] Organic and Biomolecular Chemistry, 2015, vol. 14, # 2, p. 455 - 459
[5] New Journal of Chemistry, 2018, vol. 42, # 12, p. 10142 - 10147

N-Boc-1,3-propanediamine Preparation Products And Raw materials

Raw materials

Ethylenediamine Ethanol Di-tert-butyl dicarbonate Chloroform Hydrochloric acid Dichloromethane 1,3-Diaminopropane Acetic acid Methanol Sodium hydroxide

Preparation Products

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N-Boc-1,3-propanediamine Suppliers

Americas 1 Austria 1 Belgium 2 China 327 Europe 4 France 1 Germany 7 India 25 Japan 5 Switzerland 5 United Kingdom 18 United States 62 Global 458

Suzhou Highfine Biotech Co., Ltd

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Advantage: 75

Shanghai Targsense Scientific Co., Ltd.

Tel: 18916626092
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Zepeptide Biotechnology (Shijiazhuang) Co., LTD

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Country: China
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Dancheng Huatai Biotechnology Co., Ltd.

Tel: 13482210809 13482210809
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J & K SCIENTIFIC LTD.

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Fax: 86-10-82849933
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Meryer (Shanghai) Chemical Technology Co., Ltd.

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Alfa Aesar

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Email: saleschina@alfa-asia.com
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TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
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ShangHai DEMO Chemical Co.,Ltd

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View Lastest Price from N-Boc-1,3-propanediamine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: N-Boc-1,3-propanediamine 75178-96-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-22

Henan Aochuang Chemical Co.,Ltd.

Product: N-Boc-1,3-propanediamine 75178-96-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-10

Shaanxi Dideu New Materials Co. Ltd

Product: N-Boc-1,3-propanediamine 75178-96-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-19

75178-96-0, N-Boc-1,3-propanediamineRelated Search:

Cyhalofop-butyl Diisobutyl phthalate Buprofezin Urethane 4-Aminobenzoic acid Butyl formate tert-Butanol tert-Butyl peroxybenzoate 1,2-Diaminopropane 1,3-Diaminopropane 2-Butoxyethanol Chlorpropham tert-Butyl carbamate Tamoxifen tert-Butyl carbazate butyl rubber 2,2-DIMETHYL-1,3-PROPANEDIAMINE Butyl acetate

Boc-DAP

N-t-Butyloxycarbonyl-1,3-diaminopropane

N-(3-Aminopropyl)carbamic acid tert-butyl ester ,98%

N-(3-Aminopropyl)carbamic Acid tert-Butyl Ester N-Boc-1,3-diaminopropane N-Boc-1,3-propanediamine N-(tert-Butoxycarbonyl)-1,3-propanediamine tert-Butyl N-(3-Aminopropyl)carbamate

tert-Butyl N-(3-aMiNApropyl)carbaMate

N-Boc-1,3-propanediaMine (N-Boc-1,3-diaMinopropane

N-(3-Aminopropyl)carbamic acid tert-butyl ester ,85%

tert-butyl (3-aminopropyl)carbamate(SALTDATA: FREE)

Propane-1,3-diamine, N-BOC protected

1,3-Diaminopropane, N-BOC protected, tert-Butyl (3-aminoprop-1-yl)carbamate

N-Boc-1,3-diaminopropane, tert-Butyl N-(3-aminopropyl)carbamate

tert-Butyl N-(3-aMinopropyl)ca

N-(TERT-BUTOXYCARBONYL)-1,3-DIAMINOPROPANE

N-(TERT-BUTOXYCARBONYL)-1,3-PROPANEDIAMINE

N-BOC-1,3-DIAMINOPROPANE

N-BOC-1,3-PROPANEDIAMINE

MONO-N-(T-BOC)-PROPYLENEDIAMINE

N-(3-AMINOPROPYL)CARBAMIC ACID TERT-BUTYL ESTER

1-BOC-AMINO-1,3-PROPANEDIAMINE

(3-AMINO-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER

3-(N-BOC-AMINO) PROPYLAMINE

AURORA KA-4396

BUTTPARK 27\08-80

CARBAMIC ACID, (3-AMINOPROPYL)-, 1,1-DIMETHYLETHYL ESTER

TERT-BUTYL N-(3-AMINOPROPYL)CARBAMATE

RARECHEM AR PA 0022

N-BOC-1,3-propylenediamine

N-t-BOC-1,3-PROPANEDIAMINE

Boc-1,3-Propanediamine

TERT-BUTYL N-(3-AMINOPROPYL)CARBAMATE, 9 5%

N-T-Boc-1,3-Diaminopropane

Carbamic acid, (3-aminopropyl)-, 1,1-dimethylethyl ester (9CI)

TERT-BUTYL N-(2-AMINOPROPYL)CARBAMATE

N-Boc-Propylenediamine

1,3-Diaminopropane, N1-BOC protected

tert-butyl 3-aminopropylcarbamate

N-Boc-1,3-propanediamine N-Boc-1,3-diaminopropane N-Boc-1,3-propylenediamine N-(3-Aminopropyl)carbamic acid tert-butyl ester

T BOC PROPANAMINE

N-(tert-Butoxycarbonyl)-propylenediamine

Carbamic acid, N-(3-aminopropyl)-, 1,1-dimethylethyl ester

N-Boc-1,3-propanediamine >=97.0% (GC/NT)

1-Boc-propylendiamine

Boc-1,3-diaminobutane

N-Boc-1,3-diaminopropane≥ 98%(GC)

N1-BOC-1,3-PROPANEDIAMINE

BOC propanediamine

N-(tert-Butoxycarbonyl)-1,3-diaminopropane &gt

1-Boc-1,3-propanediamine

N-Boc-1,3-propanediamine ISO 9001：2015 REACH

TIANFU CHEM N-Boc-1,3-propanediamine

Boc-NH-(CH2)3-NH2

G1-12

<i>N</i>-Boc-1,3-propanediamine

N-Boc-1,3-propanediamine, 95%

1-Boc-amino-1,3-propanediamine, 98%min

75178-96-0

5178-96-0

CH33COCONHCH23NH2