1-O-HEXADECYL-SN-GLYCEROL
- Product Name
- 1-O-HEXADECYL-SN-GLYCEROL
- CAS No.
- 506-03-6
- Chemical Name
- 1-O-HEXADECYL-SN-GLYCEROL
- Synonyms
- CHIMYL ALCOHOL;1-C16 Ether MG;1-hexadecylglycerol;1-o-hexadecylglycerol;MONOCERYL GLYCERYL ETHER;α-hexadecylglyceryl ether;1-O-HEXADECYL-SN-GLYCEROL;1-O-PALMITOYL-SN-GLYCEROL;3-cetyloxypropane-1,2-diol;3-hexadecoxypropane-1,2-diol
- CBNumber
- CB7247866
- Molecular Formula
- C19H40O3
- Formula Weight
- 316.52
- MOL File
- 506-03-6.mol
1-O-HEXADECYL-SN-GLYCEROL Property
- Melting point:
- 64°
- alpha
- D20 +3.0° (c = 1.16 in chloroform)
- Boiling point:
- bp0.005 120°
- Density
- 1.0054 (rough estimate)
- refractive index
- 1.4410 (estimate)
- storage temp.
- -15°C
- solubility
- DMF: 16 mg/ml; DMSO: 0.16 mg/ml; Ethanol: 5 mg/ml
- form
- A crystalline solid
- pka
- 13.68±0.20(Predicted)
- InChI
- InChI=1S/C19H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22-18-19(21)17-20/h19-21H,2-18H2,1H3/t19-/m0/s1
- InChIKey
- OOWQBDFWEXAXPB-IBGZPJMESA-N
- SMILES
- C(O)[C@H](O)COCCCCCCCCCCCCCCCC
- LogP
- 6.702 (est)
N-Bromosuccinimide Price
- Product number
- 25723
- Product name
- 1-O-Hexadecyl-sn-glycerol
- Purity
- ≥95%
- Packaging
- 100mg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 25723
- Product name
- 1-O-Hexadecyl-sn-glycerol
- Purity
- ≥95%
- Packaging
- 250mg
- Price
- $131
- Updated
- 2024/03/01
- Product number
- 25723
- Product name
- 1-O-Hexadecyl-sn-glycerol
- Purity
- ≥95%
- Packaging
- 500mg
- Price
- $238
- Updated
- 2024/03/01
- Product number
- 25723
- Product name
- 1-O-Hexadecyl-sn-glycerol
- Purity
- ≥95%
- Packaging
- 1g
- Price
- $356
- Updated
- 2024/03/01
- Product number
- H293755
- Product name
- 1-O-Hexadecyl-sn-glycerol
- Packaging
- 500mg
- Price
- $170
- Updated
- 2021/12/16
1-O-HEXADECYL-SN-GLYCEROL Chemical Properties,Usage,Production
Description
1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; ) in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.
Uses
1-O-Hexadecyl-sn-glycerol restores plasmalogen levels in Chinese hamster ovary (CHO) cells and human pulmonary arterial endothelial cells (PAEC). Plasmalogen may play a role in protecting animal cells against photosensitized killing.
Definition
ChEBI: A 1-n-hexadecyl analogue of an optically active alkylglycerol compound.
Purification Methods
Recrystallise it from hexane. [Beilstein 1 III 2322.]
References
[1] MARIKO YOKOTA. Chimyl Alcohol Suppresses PGE2 Synthesis by Human Epidermal Keratinocytes through the Activation of PPAR-γ.[J]. Journal of oleo science, 2018, 67 4: 455-462. DOI: 10.5650/jos.ess17157
[2] N MAULIK. Myocardial salvage by chimyl alcohol: possible role of peroxisomal dysfunction in reperfusion injury.[J]. Annals of the New York Academy of Sciences, 1994, 723: 380-384.
1-O-HEXADECYL-SN-GLYCEROL Preparation Products And Raw materials
Raw materials
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View Lastest Price from 1-O-HEXADECYL-SN-GLYCEROL manufacturers
- Product
- 1-O-Hexadecyl-sn-glycerol 506-03-6
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 50kg
- Release date
- 2025-06-24