ChemicalBook > CAS DataBase List > 6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride

6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride

Product Name
6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride
CAS No.
247016-69-9
Chemical Name
6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride
Synonyms
NVP 728;NVP DPP 728 dihydrochloride;NVP DPP 728, DPP-IV inhibitor;3-Pyridinecarbonitrile, 6-[[2-[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino]-;6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride
CBNumber
CB72518856
Molecular Formula
C15H18N6O
Formula Weight
298.34
MOL File
247016-69-9.mol
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6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride Property

Melting point:
167 °C (approx)
Boiling point:
612.1±55.0 °C(Predicted)
Density 
0.1 g/cm3
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
≥17.75 mg/mL in DMSO with gentle warming; ≥81 mg/mL in EtOH; ≥82 mg/mL in H2O
form 
oil
pka
7.47±0.20(Predicted)
color 
yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
461044
Product name
NVP DPP 728 Dihydrochloride
Packaging
1mg
Price
$396
Updated
2021/12/16
Usbiological
Product number
256079
Product name
NVP DPP 728 dihydrochloride
Packaging
10mg
Price
$480
Updated
2021/12/16
ApexBio Technology
Product number
A4427
Product name
NVPDPP728dihydrochloride
Packaging
10mM(in 1mL DMSO)
Price
$150
Updated
2021/12/16
ApexBio Technology
Product number
A4427
Product name
NVPDPP728dihydrochloride
Packaging
10mg
Price
$193
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0001520
Product name
NVP-728
Purity
95.00%
Packaging
5MG
Price
$502.45
Updated
2021/12/16
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6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride Chemical Properties,Usage,Production

Uses

NVP DPP 728 Dihydrochloride is a new potent DPP-IV inhibitor class with excellent oral bioavailability and potent antihyperglycemic activity.

target

DPP-IV

6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride Suppliers

China 32 United Kingdom 1 United States 7 Global 40
3B Pharmachem (Wuhan) International Co.,Ltd.
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247016-69-9, 6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochlorideRelated Search:

Siremadlin NVP-BAW2881 NVP-BSK805 NVP-BGT226 N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide TAE226 (NVP-TAE226) NVP-LCQ195 NVP-TAE684 NVP-BEZ 235

  • 6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitriledihydrochloride
  • NVP DPP 728 dihydrochloride
  • NVP 728
  • 3-Pyridinecarbonitrile, 6-[[2-[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino]-
  • NVP DPP 728, DPP-IV inhibitor
  • 247016-69-9
  • 247556-62-5
  • C15H18N6O2HCl