Glycitein

ChemicalBook > CAS DataBase List > Glycitein

Product Name: Glycitein
CAS No.: 40957-83-3
Chemical Name: Glycitein
Synonyms: Gycitein;GLYCITEIN;GLYCETEIN;Glicetein;Glycitein-RM;Glycitein(SH);Glycitein, >=98%;Glycitein (15 mg);Glycitein USP/EP/BP;GLYCITEIN,FROMSOYBEAN
CBNumber: CB7253674
Molecular Formula: C16H12O5
Formula Weight: 284.26
MOL File: 40957-83-3.mol

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Glycitein Property

Melting point:: >300°C
Boiling point:: 547.4±50.0 °C(Predicted)
Density: 1.420±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Aqueous Base (Slightly), DMSO (Slightly)
pka: 7.03±0.20(Predicted)
form: Solid
color: Light Brown
biological source: synthetic (organic)
InChI: InChI=1S/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
InChIKey: DXYUAIFZCFRPTH-UHFFFAOYSA-N
SMILES: C1OC2=CC(O)=C(OC)C=C2C(=O)C=1C1=CC=C(O)C=C1
LogP: 2.570 (est)
CAS DataBase Reference: 40957-83-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Safety Statements: 24/25
WGK Germany: 3
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H314Causes severe skin burns and eye damage

H331Toxic if inhaled

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL89692
Product name: Glycitein
Purity: phyproof? Reference Substance
Packaging: 10mg
Price: $316
Updated: 2024/03/01

Sigma-Aldrich

Product number: 43534
Product name: Glycitein
Purity: analytical standard
Packaging: 10mg
Price: $323
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1295844
Product name: Glycitein
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 15mg
Price: $1110
Updated: 2024/03/01

Cayman Chemical

Product number: 14162
Product name: Glycitein
Purity: ≥98%
Packaging: 5mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 14162
Product name: Glycitein
Purity: ≥98%
Packaging: 10mg
Price: $92
Updated: 2024/03/01

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Glycitein Chemical Properties,Usage,Production

Description

Glycitein is an O-methylated isoflavone that comprises 5-10% of the total isoflavones in soy food products. This phytoestrogen is reported to have weak estrogenic activity, displacing estradiol binding at the estrogen receptor in vitro with an IC₅₀ value of 3.94 μM. It suppresses the proliferation of osteoblasts and promotes differentiation from its progenitor. It has also been used to attenuate proliferation (10 μM) of aortic smooth muscle cells related to atherosclerotic vascular change in stroke-prone hypertensive rats and to protect against beta amyloid (Aβ)-induced toxicity and oxidative stress (100 μg/ml) in C. elegans expressing human Aβ.

Chemical Properties

Pale Orange Solid

Uses

Glycitein may be used as a reference standard in the determination of glycitein in hydrolyzed dry soya extracts using reversed-phase high-performance liquid chromatography (RP-HPLC).

Uses

Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.

Uses

The compund shows an anti-cancer activity, plasma cholesterol reduction, reduction in postmenopausal bone loss

Definition

ChEBI: A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 7 and 4'. It has been isolated from the mycelia of the fungus Cordyceps sinensis.

General Description

Glycitein is an isoflavone found in soy food products.

Biochem/physiol Actions

Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.

Glycitein Preparation Products And Raw materials

Raw materials

Preparation Products

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Glycitein Suppliers

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View Lastest Price from Glycitein manufacturers

Henan Fengda Chemical Co., Ltd

Product: Glycitein 40957-83-3
Price: US $8.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-29

Shanghai Standard Technology Co., Ltd.

Product: Glycitein 40957-83-3
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-10-31

Zhuozhou Wenxi import and Export Co., Ltd

Product: Glycitein 40957-83-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

40957-83-3, GlyciteinRelated Search:

Methoxydiethylborane Riboflavin 5'-Monophosphate Sodium Salt Triclosan Anisole p-Anisidine Solvent Red 43 Emodin Chrysin Curcumin (Trifluoromethoxy)benzene 1-Hydroxyethylidene-1,1-diphosphonic acid Riboflavin Theaflavin GLYCITEIN 7,4'-DIMETHYL ETHER Tectorigenin Tectoridin WISTIN Glycitin

GLYCETEIN

GLYCITEIN

4',7-DIHYDROXY-6-METHOXYISOFLAVONE

4,7-DIHYDROXY-6-METHOXYISOFLAVONE

7,4'-DIHYDROXY-6-METHOXYISOFLAVONE

Glicetein

7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one

4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-

7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-4-one

Glycitein, >=98%

Glycitein, 98%, from soybean

4μ,7-Dihydroxy-6-methoxyisoflavone, Glycetein

3-(4-Hydroxyphenyl)-6-methoxy-7-hydroxy-4H-1-benzopyran-4-one

Glycitein,4′,7-Dihydroxy-6-methoxyisoflavone, Glycetein

Glycitein (15 mg)

GLYCITEIN,FROMSOYBEAN

Glycitein USP/EP/BP

Gycitein

Glycitein, ≥97% (HPLC)

Glycitein (P) (Compendial Traceable)

4',7- Dihydroxy -6-methoxy Isoflavone (or ) GLYCITIN

7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one

GLYCITEIN (Compendial Traceable)

Glycitein(SH)

Glycitein-RM

Coumarin Impurity 9 (Coumarin 30)

Glycitein, 10 mM in DMSO

40957-83-3

40957-83-0

Nucleoside Analogs

Nucleosides, Nucleotides, Oligonucleotides

Biochemicals and Reagents

BioChemical

Intermediates & Fine Chemicals

Pharmaceuticals

The group of Daidzin

inhibitor

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Iso-Flavones