Cibenzoline succinate

Product Name: Cibenzoline succinate
CAS No.: 100678-32-8
Chemical Name: Cibenzoline succinate
Synonyms: ritmalan;ole(1:1);cipralan;Cinobezile;ro22-7796/001;Cibenzoline succinate;cibenzolinesuccinate(1:1);(+-)-2-(2,2-diphenylcyclopropyl)-2-imidazolinesuccinate(1:1);4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolsuccinate;4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolesuccinate
CBNumber: CB7255168
Molecular Formula: C22H24N2O4
Formula Weight: 380.44
MOL File: 100678-32-8.mol

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Cibenzoline succinate Property

Melting point:: 165°
storage temp.: 2-8°C
solubility: H2O: ≥5mg/mL
form: solid
color: white to off-white
Stability:: Light Sensitive

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
RTECS: EJ9960100

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C1618
Product name: Cibenzoline succinate
Purity: ≥97% (NMR), solid
Packaging: 10mg
Price: $192
Updated: 2024/03/01

Sigma-Aldrich

Product number: C1618
Product name: Cibenzoline succinate
Purity: ≥97% (NMR), solid
Packaging: 50mg
Price: $605
Updated: 2024/03/01

TRC

Product number: C535725
Product name: Cibenzoline succinate
Packaging: 5mg
Price: $115
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0002004
Product name: CIBENOL
Purity: 95.00%
Packaging: 10MG
Price: $675.51
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0002004
Product name: CIBENOL
Purity: 95.00%
Packaging: 50MG
Price: $1069.65
Updated: 2021/12/16

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Cibenzoline succinate Chemical Properties,Usage,Production

Uses

Cardiac depressant (anti-arrhythmic).

Uses

Cibenzoline Succinate acts as a highly active class I antiarrhythmic agent.

Definition

ChEBI: Cibenzoline succinate is a diarylmethane.

General Description

Cibenzoline also called (±)-2-(2,2-diphenylcyclopropyl)-2-imidazoline succinate, is generally used in stereo combination of R(+) and S(?) forms. It also exhibits anticholinergic activity.. Cibenzoline is known to improve left ventricular diastolic dysfunction by reducing left ventricular pressure gradient.

Biochem/physiol Actions

Cibenzoline is a class IA antiarrhythmic drug. Cibenzoline (μM concentrations) blocks ATP-sensitive K channels in heart and pancreatic cells. Cibenzoline interacts with the channel pore-forming subunit of the K(ATP) channel (Kir6.2) from the cytoplasmic side. Cibenzoline also inhibits the delayed rectifier K current [I(Kr)] in sino-atrial node cells.

Cibenzoline succinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Cibenzoline succinate Suppliers

China 15 Germany 3 India 1 Italy 1 Switzerland 1 United Kingdom 2 United States 9 Global 32

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15085
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 15093356674;
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30255
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49390
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-400-8210725
Email: malulu@leyan.com
Country: China
ProdList: 40041
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: 18143011203
Email: ET-market@chemextension.com
Country: China
ProdList: 30422
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42057
Advantage: 58

100678-32-8, Cibenzoline succinateRelated Search:

Cefazolin Dioctyl sulfosuccinate sodium salt 6alpha-Methylprednisolone sodium succinate Cefazolin sodium salt Tolazoline hydrochloride Dichlorodiphenylsilane Metroprolol succinate Succinic acid iron succinate 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one Disodium succinate Chlorodiphenylphosphine Imidazole Oxymetazoline hydrochloride BUTYRAMIDINE Cibenzoline Cibenzoline succinate 4-methylpentanimidamide

(+-)-2-(2,2-diphenylcyclopropyl)-2-imidazolinesuccinate(1:1)

ole(1:1)

ritmalan

ro22-7796/001

succinic acid, compound with 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole (1:2)

2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate

2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate, Cibenol, Cipralan, Exacor

Cinobezile

Cibenzoline succinate

2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidazol(+-)-1h-imidazolbutanedioate(

4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolesuccinate

4,5-dihydro-2-(2,2-diphenylcyclopropyl)-1h-imidazolsuccinate

butanedioicacid,compd.with2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidaz

butanedioicacid,compd.with2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1h-imidazole(1:1)

cibenzolinesuccinate(1:1)

cipralan

100678-32-8

C18H18N2C4H6O4

Cell Biology

Cell Signaling and Neuroscience

BioChemical

Voltage-gated Ion Channels

Potassium Channel Modulators

Ion Channels

Monovalent Ion Channels

Heterocyclic Compounds