Isoescin IB

Chemical Properties Pharmacological Action Escin Ia & Isoescin Ib

Product Name: Isoescin IB
CAS No.: 219944-46-4
Chemical Name: Isoescin IB
Synonyms: Aescin D;Escin IVb;Isoescin Ib;Isoescin IB(Isoaescin IB);Escin Impurity 4（Isoescin IB）;Aescin D，Isoescin Ib,Escin ivb;Escin,inhibit,Inhibitor,Escin IB,Isoescin IB;β-D-Glucopyranosiduronic acid, (3β,4β,16α,21β,22α)-28-(acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-;(3beta,4beta,16alpha,21beta,22alpha)-28-(Acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-beta-D-glucopyranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-4)]-beta-D-glucopyranosiduronic acid
CBNumber: CB72554315
Molecular Formula: C55H86O24
Formula Weight: 1131.26
MOL File: 219944-46-4.mol

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Isoescin IB Property

Boiling point:: 1148.1±65.0 °C(Predicted)
Density: 1.46
solubility: Soluble in methanol;
pka: 2.63±0.70(Predicted)
form: powder
color: White
Water Solubility: slightly soluble in water

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL83863
Product name: Isoescin IB
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $709
Updated: 2024/03/01

Usbiological

Product number: 300477
Product name: Isoescin IB
Packaging: 5mg
Price: $490
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb259321
Product name: Isoescin IB
Purity: 95%
Packaging: 10mg
Price: $552.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FI145247
Product name: Isoescin IB
Packaging: 2mg
Price: $98.76
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FI145247
Product name: Isoescin IB
Packaging: 5mg
Price: $197.5
Updated: 2021/12/16

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Isoescin IB Chemical Properties,Usage,Production

Chemical Properties

The saponins found in escin exist in two forms, β-escin and α-escin, which can be distinguished by melting point, hemolytic index, specific rotation and solubility in water. β-Escin (mainly consisting of escin Ia and escin Ib) is the major active ingredient in horse chestnut seeds extracts.

Pharmacological Action

Escin exhibits remarkable anti-inflammatory, anti-edematous and vasoprotective properties in a dose-dependent manner which are quite evident at 10-6–10-7 M. Escin has been traditionally used to treat conditions such as chronic venous insufficiency, hemorrhoids, inflammation and cerebral ischemic damage.

Escin Ia & Isoescin Ib

As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity. Similar to isoescin Ia is the isomer of escin Ia, Isoescin Ib is an isomer of escin Ib. Both of them were found to be isomerizable in vitro. Escin Ib and isoescin Ib exhibits stronger pharmacological activity than escin Ia and isoescin Ia. As the result, pharmacokinetics study of them would be helpful for improving the practice of escin application.

Isoescin IB Preparation Products And Raw materials

Raw materials

Preparation Products

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Isoescin IB Suppliers

China 89 India 3 United Kingdom 1 United States 11 Global 104

BOC Sciences

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EMMX Biotechnology LLC

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BOC Sciences

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TargetMol Chemicals Inc.

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Aladdin Scientific

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TargetMol Chemicals Inc.

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United States Biological

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MedChemExpress

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FortopChem Technology Limited

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View Lastest Price from Isoescin IB manufacturers

Career Henan Chemical Co

Product: Aescin D 219944-46-4
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 1000kg
Release date: 2018-12-25

219944-46-4, Isoescin IBRelated Search:

Escin escin IIa GYPENOSIDE-XVII Gypenoside XLVI AESCIN IB(SH) Escin, monosodium salt salviaflaside Isoescin Ie Isoastragaloside IV Isoginsenoside Rh3 isocucurbitacin B Ginsenoside Rg3 Notoginsenoside R1 Ginsengrootextract AESCIN IA(SH) (3beta,4beta,16alpha,21beta,22alpha)-28-(Acetyloxy)-16,22,23-trihydroxy-21-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-beta-D-glucopyranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-4)]-beta-D-glucopyranosiduronic acid Escin Ie ESCIN IIB

Aescin D

Escin IVb

Isoescin Ib

Isoescin IB(Isoaescin IB)

(3beta,4beta,16alpha,21beta,22alpha)-28-(Acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-beta-D-glucopyranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-4)]-beta-D-glucopyranosiduronic acid

Escin Impurity 4（Isoescin IB）

β-D-Glucopyranosiduronic acid, (3β,4β,16α,21β,22α)-28-(acetyloxy)-16,22,23-trihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-

Escin,inhibit,Inhibitor,Escin IB,Isoescin IB

Aescin D，Isoescin Ib,Escin ivb

219944-46-4