ChemicalBook > CAS DataBase List > 7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine

7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine

Product Name
7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine
CAS No.
1379666-94-0
Chemical Name
7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine
Synonyms
Sitagliptin-1;N-Acetyl Sitagliptin;Sitagliptin Impurity 37;Sitagliptin N-Acetyl Imp;Sitagliptin EP Impurity D;(R)-N-(4-oxo-4-(3-(trifluoromethyl);Sitagliptin N-Acetyl Impurity Sitagliptin impurity D;Sitagliptin N-Acetyl Impurity / N-Acetyl Sitagliptin;(R)-N-(4-oxo-4-(3-(trifluoroMethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)acetaMide;7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine
CBNumber
CB72621905
Molecular Formula
C18H17F6N5O2
Formula Weight
449.35
MOL File
1379666-94-0.mol
More
Less

7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine Property

Melting point:
82-85°C
storage temp. 
Refrigerator, under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
A187815
Product name
N-AcetylSitagliptin
Packaging
5mg
Price
$150
Updated
2021/12/16
Usbiological
Product number
001565
Product name
N-Acetyl Sitagliptin
Packaging
5mg
Price
$460
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
49395
Product name
N-AcetylSitagliptin
Packaging
5mg
Price
$650
Updated
2021/12/16
AK Scientific
Product number
2899DM
Product name
N-AcetylSitagliptin
Packaging
100mg
Price
$3830
Updated
2021/12/16
More
Less

7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine Chemical Properties,Usage,Production

Uses

N-Acetyl Sitagliptin is the N-acetylated derivative of the trizolopyrazine dipeptidyl peptidase IV inhibitor, Sitagliptin (S491000).

7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-010-52878169 15801002657
Email
sales@bjcomparison.com
Country
China
ProdList
4815
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18097
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Chengdu Miracle Pharmaceutical Co., Ltd.
Tel
028-86136736 19130631884
Fax
028-85265615
Email
sales@mic-pharma.com
Country
China
ProdList
291
Advantage
56
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7892
Advantage
55
XinYao(Shenzhen) Biological Technology Co., Ltd.
Tel
0755-89880280
Fax
0755-89880280
Email
3004662104@qq.com
Country
China
ProdList
1829
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57423
Advantage
58
Guangzhou Dreampharm Biotechnology Co., Ltd.
Tel
020-36607679 17825480238
Fax
QQ 3008233717
Email
3008233746@qq.com
Country
China
ProdList
9919
Advantage
12
sgtlifesciences pvt ltd
Tel
+8617013299288
Email
dj@sgtlifesciences.com
Country
China
ProdList
12373
Advantage
58
Hangzhou Huarong Pharm Co., Ltd.
Tel
571-86758373 +8613588754946
Fax
0086-571-81131109
Email
sales@huarongpharm.com
Country
CHINA
ProdList
3148
Advantage
58
Jinan blalong chemical co. LTD
Tel
2710913286@.com
Email
1513643261@qq.com
Country
China
ProdList
14246
Advantage
58
Shanghai Payne Pharmaceutical Technology Co.Ltd
Tel
021-58123769 17721400256
Email
info@paynepharm.com
Country
China
ProdList
1285
Advantage
58
Shanghai Payne Pharmaceutical Technology Co.Ltd
Tel
021-58123769 18678586262
Email
info@paynepharm.com
Country
China
ProdList
1354
Advantage
58
Shenzhen ruikai de biotechnology co., ltd.
Tel
0755-61348847 17820674378
Fax
0755-21016893
Email
2682116078@qq.com
Country
China
ProdList
7843
Advantage
58
Wuxi Helen Biotechnology Co., Ltd.,
Tel
0510-85629785 18013409632
Fax
0510-85625359
Email
sales@reading-chemicals.com
Country
China
ProdList
14081
Advantage
58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD
Tel
0755-0755-0755-83725350 13380397412
Fax
0755-28094224
Email
3001280422@qq.com
Country
China
ProdList
10005
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
info@synzest.com
Country
China
ProdList
9286
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44807
Advantage
58
Guangzhou Juntang Technology Co., Ltd
Tel
020-36607679 13502246435
Email
sales@dmstandards.com
Country
China
ProdList
10945
Advantage
58
Jiangsu Wansipu Technology Co., Ltd.
Tel
17826022701
Email
1485609990@qq.com
Country
China
ProdList
965
Advantage
58
Foshan Treasure Biotechnology Co., Ltd
Tel
0757-85921206 18520245316
Email
2329783215@qq.com
Country
China
ProdList
12661
Advantage
58
Changzhou Xianglong Pharmaceutical Technology Co., LTD
Tel
0519-88910898 18661161657
Email
yaoxiangqiu2021@163.com
Country
China
ProdList
9996
Advantage
58
QUALITY CONTROL SOLUTIONS LTD.
Tel
0755-66853366; 13670046396
Email
ORDERS@QCSRM.COM
Country
China
ProdList
24342
Advantage
58
Henan Kehong Biological Technology Co. LTD
Tel
0371-55969461; 0371-86658258 19139748274
Fax
QQ:3311217266
Email
info@kehobio.com
Country
China
ProdList
2555
Advantage
58
Molcoo Chemicals Inc.
Tel
18576690171
Email
3001025734@qq.com
Country
China
ProdList
11429
Advantage
58
Hunan Zengda Biological Technology Co., LTD
Tel
18711085600
Email
1652923704@qq.com
Country
China
ProdList
4592
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
18351873721
Email
helen.zhang@synzest.com
Country
China
ProdList
8295
Advantage
58
Scinova Biotech(Guangzhou) Co., Ltd.
Tel
13268215580
Email
scinova_sales@163.com
Country
China
ProdList
7025
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81960175-877 18933936954
Email
tianwen.zhan@cato-chem.com
Country
China
ProdList
7734
Advantage
58
LGC Science (Shanghai) Ltd.
Tel
17717235263
Email
cindy.yang@lgcgroup.com
Country
China
ProdList
17730
Advantage
58
HX Pharmaceutical technology co., LTD
Tel
15671363360
Email
494267389@qq.com
Country
China
ProdList
3685
Advantage
58
Shanghai Haohong Scientific Co., Ltd.
Tel
400-400-8210725 17717813675;
Email
malulu@leyan.com
Country
China
ProdList
39988
Advantage
58
Shenzhen Excellent Biomedical Technology Co., Ltd.
Tel
18318671572
Email
2850803126@qq.com
Country
China
ProdList
5004
Advantage
58
Shanghai Zerui Biotechnology Co., Ltd.
Tel
021-54580889 18321124657
Fax
021-54580889
Email
731997554@qq.com
Country
China
ProdList
10608
Advantage
58
JiNan QiYuan Biotechnology Co., Ltd
Tel
18766124282; 18766124282
Email
18766124282@163.COM
Country
China
ProdList
866
Advantage
58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd
Tel
18502726233; 18502726233
Email
3641133981@qq.com
Country
China
ProdList
9713
Advantage
58
Wuhan Acumen Bio-Technology Co.,ltd
Tel
027-027-16602739303 16602739303
Email
673003916@qq.com
Country
China
ProdList
2974
Advantage
58
Shenzhen Qingtian Biotechnology Co, Ltd.
Tel
18823167005 18162969855
Email
744288988@qq.com
Country
China
ProdList
2629
Advantage
58
ShenZhen H&D Pharmaceutical Technology Co., LTD
Tel
13217415044
Email
wangshuai@hdimpurity.com
Country
China
ProdList
7918
Advantage
58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
18616537568
Email
hanfangpharma@126.com
Country
China
ProdList
29981
Advantage
58
Hubei Moco Chemical Co., Ltd.
Tel
18627753421 18627756402
Fax
QQ:3001051413
Email
3001009495@qq.com
Country
China
ProdList
19081
Advantage
58
Cato Research Chemicals Inc.
Tel
13342851930
Email
3008394369@qq.com
Country
China
ProdList
15726
Advantage
58
Huaihua Yuanyanda Biotechnology Co., Ltd
Tel
18229999901
Email
18711085600@163.com
Country
China
ProdList
4590
Advantage
58
Moxin Chemicals
Tel
+8617320513646
Email
mike@molcoo.com
Country
China
ProdList
9606
Advantage
58
China National Standard Pharmaceutical Corporation Limited
Tel
+8615391658522
Email
overseasales@yongstandards.com
Country
China
ProdList
11922
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58

1379666-94-0, 7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazineRelated Search:


  • 7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine
  • N-Acetyl Sitagliptin
  • N-[(1R)-3-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]acetamide
  • (R)-N-(4-oxo-4-(3-(trifluoroMethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)acetaMide
  • Sitagliptin Impurity 37
  • Sitagliptin EP Impurity D
  • Sitagliptin impurity 14/Sitagliptin N-Acetyl Impurity/N-Acetyl Sitagliptin/7-[(3R)-3-[(N-Acetyl)amino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine
  • Sitagliptin-1
  • (R)-N-(4-oxo-4-(3-(trifluoromethyl)
  • Acetamide, N-[(1R)-3-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]-
  • (R)-N-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)acetamide? (Sitagliptin Impurity)
  • Sitagliptin N-Acetyl Imp
  • Sitagliptin N-Acetyl Impurity Sitagliptin impurity D
  • Sitagliptin N-Acetyl Impurity / N-Acetyl Sitagliptin
  • 1379666-94-0
  • C18H17F6N5O2
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals