ChemicalBook > CAS DataBase List > PeMetrexed EP IMpurity E

PeMetrexed EP IMpurity E

Product Name
PeMetrexed EP IMpurity E
CAS No.
182009-04-7
Chemical Name
PeMetrexed EP IMpurity E
Synonyms
Pemetrexed R-Isomer;Pemetrexed EP Imp E;Pemetrexed Impurity 10;Pemetrexed BP Impurity E;Pemetrexed EP Impurity E;Pemetrexed EP Impurity E (R-Pemetrexed);Pemetrexed EP Impurity E (Pemetrexed Enantiomer);D-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-;(R)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid;(R)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid? (Pemetrexed Impurity)
CBNumber
CB72630466
Molecular Formula
C20H21N5O6
Formula Weight
427.41
MOL File
182009-04-7.mol
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PeMetrexed EP IMpurity E Property

Density 
1.59±0.1 g/cm3(Predicted)
pka
3.58±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H341Suspected of causing genetic defects

H360May damage fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Ambeed
Product number
A1026423
Product name
(2R)-2-{[4-(2-{2-amino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}pentanedioicacid
Purity
98+%
Packaging
1g
Price
$934
Updated
2021/12/16
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PeMetrexed EP IMpurity E Chemical Properties,Usage,Production

Uses

(R)-Pemetrexed is related to the compound Pemetrexed(A604980); used in the treatment of malignant pleural mesothelioma (MPM).

Definition

ChEBI: (2R)-2-[[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]phenyl]-oxomethyl]amino]pentanedioic acid is a glutamic acid derivative.

PeMetrexed EP IMpurity E Preparation Products And Raw materials

Raw materials

Preparation Products

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182009-04-7, PeMetrexed EP IMpurity ERelated Search:


  • (R)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid
  • Pemetrexed BP Impurity E
  • Pemetrexed Impurity 10
  • Pemetrexed EP Imp E
  • Pemetrexed impurity 4/Pemetrexed EP Impurity E/(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-D-glutamic acid
  • D-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-
  • Pemetrexed R-Isomer
  • Pemetrexed EP Impurity E (R-Pemetrexed)
  • (R)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid? (Pemetrexed Impurity)
  • Pemetrexed EP Impurity E
  • Pemetrexed EP Impurity E (Pemetrexed Enantiomer)
  • 182009-04-7