5-Methoxy-2,3-dihydroindoline
- Product Name
- 5-Methoxy-2,3-dihydroindoline
- CAS No.
- 21857-45-4
- Chemical Name
- 5-Methoxy-2,3-dihydroindoline
- Synonyms
- 5-Methoxyindoline;5-METHOXYLINDOLINE; 5-Methoxy-2,3-dihydroindolin;5-METHOXY-2,3-DIHYDROINDOLINE;5-METHOXY-2,3-DIHYDRO-1H-INDOLE;1H-INDOLE, 2,3-DIHYDRO-5-METHOXY-;5-Methoxy-2,3-dihydro-1H-indoline;5-Methoxyindoline 5-Methoxy-2,3-dihydroindoline in stock Factory
- CBNumber
- CB7267569
- Molecular Formula
- C9H11NO
- Formula Weight
- 149.19
- MOL File
- 21857-45-4.mol
5-Methoxy-2,3-dihydroindoline Property
- Boiling point:
- 282.6±29.0 °C(Predicted)
- Density
- 1.076±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- solid
- pka
- 6.07±0.20(Predicted)
- Appearance
- Light yellow to brown Liquid
- CAS DataBase Reference
- 21857-45-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- M265463
- Product name
- 5-Methoxy-2,3-dihydro-1H-indole
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CHM0012745
- Product name
- 5-METHOXY-2,3-DIHYDRO-1H-INDOLE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $736.12
- Updated
- 2021/12/16
- Product number
- CHM0012745
- Product name
- 5-METHOXY-2,3-DIHYDRO-1H-INDOLE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1011.6
- Updated
- 2021/12/16
- Product number
- CHM0012745
- Product name
- 5-METHOXY-2,3-DIHYDRO-1H-INDOLE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1210.63
- Updated
- 2021/12/16
- Product number
- W4513
- Product name
- 5-Methoxy-2,3-dihydro-1H-indoline
- Packaging
- 25g
- Price
- $1453
- Updated
- 2021/12/16
5-Methoxy-2,3-dihydroindoline Chemical Properties,Usage,Production
Synthesis
1006-94-6
21857-45-4
5-Methoxyindole (1.5 g, 10.2 mmol) was dissolved in acetic acid (20 mL) at 25 °C, followed by the addition of sodium cyanoborohydride (0.77 g, 12.2 mmol) in batches. After the reaction lasted for 1 h, the pH of the reaction solution was adjusted to 9-10 with 20% sodium hydroxide solution for neutralization. The reaction mixture was extracted with ethyl acetate (50 mL) and the organic phase was separated and dried over anhydrous sodium sulfate. The dried organic phase was filtered and the filtrate was concentrated by rotary evaporation. Finally, 5-methoxyindoline was purified by column chromatography (eluent: petroleum ether/ethyl acetate, 10:1, v/v) to afford 5-methoxyindoline as a brown solid (1.46 g, 95.9% yield).
References
[1] Organic Letters, 2011, vol. 13, # 19, p. 5124 - 5127
[2] Chemical Communications, 2013, vol. 49, # 63, p. 7052 - 7054
[3] Patent: CN105367474, 2016, A. Location in patent: Paragraph 0194; 0195; 0196; 0197
[4] Journal of Medicinal Chemistry, 1997, vol. 40, # 4, p. 479 - 485
[5] Patent: EP1223170, 2002, A1
5-Methoxy-2,3-dihydroindoline Preparation Products And Raw materials
Raw materials
Preparation Products
5-Methoxy-2,3-dihydroindoline Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
View Lastest Price from 5-Methoxy-2,3-dihydroindoline manufacturers
- Product
- 5-Methoxyindoline 21857-45-4
- Price
- US $1.10-9.90/KG
- Min. Order
- 1KG
- Purity
- 99% min
- Supply Ability
- 100kg
- Release date
- 2025-08-18
- Product
- 5-Methoxyindoline 5-Methoxy-2,3-dihydroindoline in stock Factory 21857-45-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- TOP 3 Factory in China
- Supply Ability
- Top 3 production capacity Factory
- Release date
- 2019-04-03
- Product
- 5-Methoxy-2,3-dihydroindoline 21857-45-4
- Price
- US $8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10tons
- Release date
- 2018-12-24