ChemicalBook > CAS DataBase List > Glatiramer acetate

Glatiramer acetate

Product Name
Glatiramer acetate
CAS No.
147245-92-9
Chemical Name
Glatiramer acetate
Synonyms
ProtiraMer;GlatiraMer-d7;Glatirameracetat;GaltiraMer acetate;GLATIRAMER ACETATE;Chloramine B 127-52-6;Glatiramer acetate API;Glatiramer acetate USP/EP/BP;Glatiramer acetate [USAN:BAN];Pharmaceutical Glatiramer acetate
CBNumber
CB7285192
Molecular Formula
C25H45N5O13
Formula Weight
623.66
MOL File
147245-92-9.mol
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Glatiramer acetate Property

Melting point:
>239°C (dec.)
storage temp. 
Refrigerator
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
CAS DataBase Reference
147245-92-9(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P285In case of inadequate ventilation wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
9000571
Product name
Glatiramer (acetate)
Purity
≥95%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
9000571
Product name
Glatiramer (acetate)
Purity
≥95%
Packaging
5mg
Price
$134
Updated
2024/03/01
Cayman Chemical
Product number
9000571
Product name
Glatiramer (acetate)
Purity
≥95%
Packaging
10mg
Price
$231
Updated
2024/03/01
Cayman Chemical
Product number
9000571
Product name
Glatiramer (acetate)
Purity
≥95%
Packaging
25mg
Price
$397
Updated
2024/03/01
Usbiological
Product number
012799
Product name
Glatiramer Acetate
Packaging
5mg
Price
$276
Updated
2021/12/16
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Glatiramer acetate Chemical Properties,Usage,Production

Originator

Copaxone,Teva Pharmaceuticals,Israel

Uses

Glatiramer Acetate-Dx is labelled Glatiramer Acetate (G406800) which is a random basic synthetic copolymer of L-alanine, L-lysine, l-glutamic acid and L-tyrosine. Glatiramer acetate is an immunomodulator used in treatment of multiple sclerosis.

Uses

Glatiramer acetate is a random basic synthetic copolymer of L-alanine, L-lysine, l-glutamic acid and L-tyrosine in a molar ratio of 6:1.9:4.7:1. Glatiramer acetate is an immunomodulator used in treatment of multiple sclerosis.

Manufacturing Process

Glatiramer Acetate is water soluble copolypeptide with molecular weight 15,000-25,000.
Copolymer is prepared by copolymerization of the N-carboxyanhydrides of tyrosine, alanine, lysine, and glutamic acid. The polymerisation was carried out at ambient temperature in anhydrous dioxane with diethylamine as initiator. Glatiramer Acetate have the ratio alanin:glutamic acid:lysine:tyrosine = 1:6:4.54:2.

brand name

Copaxone (Teva).

Therapeutic Function

Immunomodulator

Clinical Use

Immunomodulating drug:

Treatment for patients at a high risk of developing multiple sclerosis and for reduction in relapses in ambulatory patients

Metabolism

A substantial fraction of a subcutaneous dose of glatiramer is believed to be hydrolysed locally. Some of the injected dose is also presumed to enter the lymphatic system, either intact or partially hydrolysed.

Glatiramer acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Glatiramer acetate manufacturers

Sigma Audley
Product
Glatiramer acetate 147245-92-9
Price
US $35.00-25.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
200tons/year
Release date
2024-03-15
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Glatiramer acetate 147245-92-9
Price
US $0.00/kit
Min. Order
1g
Purity
97.0%~105.0%
Supply Ability
1500g/month
Release date
2021-06-05
Henan Bao Enluo International TradeCo.,LTD
Product
Glatiramer acetate 147245-92-9
Price
US $15.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000tons
Release date
2023-06-15

147245-92-9, Glatiramer acetateRelated Search:


  • GLATIRAMER ACETATE
  • l-glutamic acid polymer with l-alanine, l-lysine and l-tyrosine, acetate (salt)
  • 511: PN: WO2010103292 PAGE: 64 claiMed sequence
  • L-Alanine polyMer with L-GlutaMic Acid L-Lysine L-Tyrosine Acetate
  • L-GlutaMic Acid peptide with L-Alanine L-Lysine L-Tyrosine Acetate Salt
  • L-Tyrosine polyMer with L-Alanine L-GlutaMic Acid L-Lysine Acetate
  • ProtiraMer
  • GaltiraMer acetate
  • GlatiraMer-d7
  • Glatiramer acetate [USAN:BAN]
  • acetic acid,(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid,(2S)-2-aminopentanedioic acid,(2S)-2-aminopropanoic acid,(2S)-2,6-diaminohexanoic acid
  • Pharmaceutical Glatiramer acetate
  • aceticacid,(2S)-2-amino-3-(4-hydroxyphenyl)propanoicacid,(2S)-2-aminopentanedioicacid,(2S)-2-aminopropanoicacid,(2S)-2,6-diaminohexanoicaci
  • Glatiramer acetate USP/EP/BP
  • Glatirameracetat
  • Glatiramer acetate API
  • Chloramine B 127-52-6
  • 147245-92-9
  • C25H45N5O13
  • C9H11NO3C6H14N2O2C5H9NO4C3H7NO2XxC2H4O2
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  • API