ChemicalBook > CAS DataBase List > 3,4-Methylenedioxyacetophenone

3,4-Methylenedioxyacetophenone

Product Name: 3,4-Methylenedioxyacetophenone
CAS No.: 3162-29-6
Chemical Name: 3,4-Methylenedioxyacetophenone
Synonyms: 1-(benzo[d][1,3]dioxol-5-yl)ethanone;ACETOPIPERONE;1-(1,3-Benzodioxol-5-yl)ethanone;Moskachan A;TIMTEC-BB SBB007858;3,4-Methylenedioxyac;3,4-(Methylenedioxy);LABOTEST-BB LT00053586;Paroxetine Impurity 72;Paroxetine impurities796
CBNumber: CB7301311
Molecular Formula: C9H8O3
Formula Weight: 164.16
MOL File: 3162-29-6.mol

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3,4-Methylenedioxyacetophenone Property

Melting point:: 87-89 °C(lit.)
Boiling point:: 152-155°C 15mm
Density: 1.2132 (rough estimate)
refractive index: 1.5260 (estimate)
Flash point:: 152-155°C/15mm
storage temp.: Inert atmosphere,Room Temperature
form: Crystalline Powder
color: Beige
Odor: Heavy, sweet-floral and warm-herbaceous odor
Water Solubility: Slightly soluble in water.
BRN: 139669
InChI: InChI=1S/C9H8O3/c1-6(10)7-2-3-8-9(4-7)12-5-11-8/h2-4H,5H2,1H3
InChIKey: BMHMKWXYXFBWMI-UHFFFAOYSA-N
SMILES: C(=O)(C1=CC=C2OCOC2=C1)C
CAS DataBase Reference: 3162-29-6(CAS DataBase Reference)
NIST Chemistry Reference: 3',4'-(Methylenedioxy)acetophenone(3162-29-6)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 37/39-26-36-24/25
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 274801
Product name: 3′,4′-(Methylenedioxy)acetophenone
Purity: 98%
Packaging: 5g
Price: $61.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: 274801
Product name: 3′,4′-(Methylenedioxy)acetophenone
Purity: 98%
Packaging: 25g
Price: $199
Updated: 2025/07/31

TCI Chemical

Product number: M0874
Product name: 3',4'-(Methylenedioxy)acetophenone
Purity: >98.0%(GC)
Packaging: 25g
Price: $167
Updated: 2025/07/31

TRC

Product number: M219625
Product name: 3'',4''-(Methylenedioxy)acetophenone
Packaging: 2.5g
Price: $75
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK361257
Product name: 3',4'-(Methylenedioxy)acetophenone
Purity: 98%
Packaging: 5g
Price: $18
Updated: 2021/12/16

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3,4-Methylenedioxyacetophenone Chemical Properties,Usage,Production

Chemical Properties

Colorless or white crystals. M.P. 89℃. Almost insoluble in water, soluble in alcohol and oils.

Uses

3?,4?-(Methylenedioxy)acetophenone is used in the synthesis of N-ethyl-1-(3,4-methylenedioxyphenyl)ethylamine.

Uses

3′,4′-(Methylenedioxy)acetophenone was used in the synthesis of N-ethyl-1-(3,4-methylenedioxyphenyl)ethylamine.

Definition

ChEBI: 3,4-Methylenedioxyacetophenone is a member of benzodioxoles.

Synthesis Reference(s)

Journal of the American Chemical Society, 79, p. 4507, 1957 DOI: 10.1021/ja01573a069

Synthesis

3,4-Methylenedioxyacetophenone's synthesis method: 1) from Piperonylic acid plus Acetic acid vapors at high temperature over catalyst (Thoria, e.g.). 2) from alpha-Methylpiperonylic acid by oxidation.

References

[1] Synthesis, 1980, # 9, p. 691 - 694
[2] European Journal of Medicinal Chemistry, 2015, vol. 105, p. 80 - 105
[3] Synthetic Communications, 2014, vol. 44, # 14, p. 2076 - 2087
[4] Tetrahedron Letters, 2000, vol. 41, # 42, p. 8131 - 8135
[5] Chemical and Pharmaceutical Bulletin, 1985, vol. 33, # 11, p. 4775 - 4782

3,4-Methylenedioxyacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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3,4-Methylenedioxyacetophenone Suppliers

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View Lastest Price from 3,4-Methylenedioxyacetophenone manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3,4-Methylenedioxyacetophenone 3162-29-6
Price: US $1.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-08

Zhuozhou Wenxi import and Export Co., Ltd

Product: (3.4-Methylenedioxy)acetophenone 3162-29-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: (3.4-Methylenedioxy)acetophenone 3162-29-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

3162-29-6, 3,4-MethylenedioxyacetophenoneRelated Search:

Acetylacetone 4-Nitroacetophenone 1,3-Benzodioxole 4'-Bromoacetophenone 2-Bromoacetophenone Chalcone 4'-Methylacetophenone Acetophenone 4'-Hydroxyacetophenone Acetyl chloride 3-Nitroacetophenone paroxetine Mesylate Paroxetine Impurity 5 Paroxetine Related Impurity 7 3S4R 3S,4R-4-[phenyl-1-methylpiperidinyl] methanol 1,3-Benzodioxol-4-ol Paroxetine Impurity 16 4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine

1-(1,3-Benzodioxol-5-yl)ethanone

3,4-Methylen-dioxy-acetophenon

Methyl (1,3-benzodioxole-5-yl) ketone

Moskachan A

3,4-Methylenedioxyacetophenone,98%

3,4-Methylenedioxyac

3,4-Methylenedioxyacetophenone, 98% 5GR

3',4'-(Methylenedioxy)acetophenone 98%

TIMTEC-BB SBB007858

3,4-(METHYLENEDIOXY)ACETOPHENONE

3,4-METHYLENDIOXYACETOPHENONE

4-ACETYLMETHYLENEDIOXYBENZENE

5-ACETYL-1,3-BENZODIOXOLE

ACETOPIPERONE

1-(BENZ[1,3]DIOXOL-5-YL)ETHANONE

ETHANONE, 1-(1,3-BENZODIOXOL-5-YL)-

LABOTEST-BB LT00053586

1-(1,3-benzodioxol-5-yl)ethan-1-one

3,4-Methylendioxyactophenone

1-(benzo[d][1,3]dioxol-5-yl)ethanone

3,4-Methylendioxybenzylmethylketon

3,4-(Methylenedioxy)

3,4-Methylendioxyactophenone 98%

1-(1,3-BENZODIOXOL-5-YL)-1-ETHANONE

1,3-Benzodioxol-5-yl (methyl) ketone

M**3',4'-(METHYLENEDIOXY)ACETOPHENONE

3',4'-(Methylenedioxy)acetophenone&gt

1-(Benzo[d][1,3]dioxol-5-yl)ethanone (Paroxetine Impurity)

Paroxetine impurities796

Paroxetine Impurity 72

CAS 3162-29-6 3,4-Methylenedioxyacetophenone

1-(benzo[d][1,3]dioxol-6-yl)ethanone

3',4'-(Methylenedioxy)acetophenone

5-Acetylbenzo[d][1,3]dioxole

3162-29-6

3162-29-61

KETONE

Building Blocks

Carbonyl Compounds

Organic Building Blocks

Ketones

Adehydes, Acetals & Ketones

Carbonyl Compounds

Ketones

Aromatic Acetophenones & Derivatives (substituted)