ChemicalBook > CAS DataBase List > Bromo-PEG1-Acid

Bromo-PEG1-Acid

Product Name
Bromo-PEG1-Acid
CAS No.
1393330-33-0
Chemical Name
Bromo-PEG1-Acid
Synonyms
Bromo-PEG1-Acid;CAS_1393330-33-0;Br-PEG1-CH2CH2COOH;Bromo-PEG1-acid >=95%;Bromo-PEG1-propionic acid;3-(2-Bromoethoxy)propanoic acid;Propanoic acid, 3-(2-bromoethoxy)-
CBNumber
CB73062435
Molecular Formula
C5H9BrO3
Formula Weight
197.03
MOL File
1393330-33-0.mol
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Bromo-PEG1-Acid Property

storage temp. 
-20°C
solubility 
DMSO : 100 mg/mL (507.54 mM; Need ultrasonic)
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Safety

HS Code 
2918999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
901573
Product name
Bromo-PEG1-acid
Purity
≥95%
Packaging
50MG
Price
$200
Updated
2023/06/20
TRC
Product number
B800380
Product name
Bromo-PEG1-Acid
Packaging
50mg
Price
$240
Updated
2021/12/16
TRC
Product number
B800380
Product name
Bromo-PEG1-Acid
Packaging
5mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
POL0002405
Product name
BROMO-PEG1-ACID
Purity
95.00%
Packaging
100MG
Price
$393.75
Updated
2021/12/16
Apolloscientific
Product number
BIPG1321
Product name
Bromo-PEG1-Acid
Packaging
100mg
Price
$428
Updated
2021/12/16
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Bromo-PEG1-Acid Chemical Properties,Usage,Production

Description

Bromo-PEG1-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Bromo-PEG1-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG1-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

Bromo-PEG1-Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Bromo-PEG1-Acid Suppliers

PharmaBlock Sciences (Nanjing),Inc.
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Energy Chemical
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View Lastest Price from Bromo-PEG1-Acid manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Br-PEG1-acid 1393330-33-0
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-25

1393330-33-0, Bromo-PEG1-AcidRelated Search:


  • Bromo-PEG1-propionic acid
  • Bromo-PEG1-Acid
  • CAS_1393330-33-0
  • Br-PEG1-CH2CH2COOH
  • 3-(2-Bromoethoxy)propanoic acid
  • Propanoic acid, 3-(2-bromoethoxy)-
  • Bromo-PEG1-acid >=95%
  • 1393330-33-0