Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer

Product Name: Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer
CAS No.: 219649-07-7
Chemical Name: Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer
Synonyms: Labetuzumab;Labetuzumab (anti-CEACAM5);Research Grade Labetuzumab;IMMU-14|||hMN-14|||IMMU-100;Research Grade Labetuzumab(DHC21001);Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer
CBNumber: CB73206493
Formula Weight: 0
MOL File: Mol file

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Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer Chemical Properties,Usage,Production

Uses

Treatment of colorectal cancer (humanized monoclonal antibody hMN-14 targeting CEA- positive cancers).

brand name

CEA-CIDE (Immunomedics).

in vivo

Labetuzumab (0.5 mg/rat; i.v.; single) inhibits tumor growth in vivo^[1].

Animal Model:	Female nu/nu mice (6 to 8-week-old; inject TT cells)^[1].
Dosage:	0.5 mg/rat
Administration:	Intravenous injection; single (1 day post-tumor cell injection)
Result:	Significantly delaied growth of tumor, and led to 64%-70% inhibition of tumor size between days 32 and 60.

Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer Preparation Products And Raw materials

Raw materials

Preparation Products

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Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer Suppliers

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219649-07-7, Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimerRelated Search:

Bemarituzumab varlilumab Lucatumumab Netakimab Landogrozumab Ieramilimab Marstacimab Margetuximab Enokizumab Inebilizumab

Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer

Labetuzumab

Research Grade Labetuzumab(DHC21001)

IMMU-14|||hMN-14|||IMMU-100

Research Grade Labetuzumab

Labetuzumab (anti-CEACAM5)

219649-07-7