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BOC-THR-OH DCHA

Product Name
BOC-THR-OH DCHA
CAS No.
23082-30-6
Chemical Name
BOC-THR-OH DCHA
Synonyms
Boc-allo-Thr-OH;(2S,3S)-2-((tert-Butoxycarbonyl)aMino)-3-hydroxybutanoic acid;N-Boc-L-Allothreonine;BOC-THR-OH DCHA;Boc-Allo-Thr.DCHA;Boc-L-allo-Thr-OH;BOC-L-allothreonine;BOC-L-THREONINE DCHA;BOC-ALLO-THR-OH DCHA;BOC-L-ALLO-THR-OH DCHA
CBNumber
CB7335282
Molecular Formula
C9H17NO5
Formula Weight
219.24
MOL File
23082-30-6.mol
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BOC-THR-OH DCHA Property

Boiling point:
387.1±37.0 °C(Predicted)
Density 
1.202±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
3.60±0.10(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-W005847
Product name
(2S,3S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxybutanoicacid
Purity
>97.0%
Packaging
250mg
Price
$55
Updated
2021/12/16
ChemScene
Product number
CS-W005847
Product name
(2S,3S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxybutanoicacid
Purity
>97.0%
Packaging
1g
Price
$109
Updated
2021/12/16
Iris Biotech GmbH
Product number
BAA1339
Product name
Boc-L-allo-Thr-OH*DCHA
Packaging
1g
Price
$270
Updated
2021/12/16
ChemScene
Product number
CS-W005847
Product name
(2S,3S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxybutanoicacid
Purity
>97.0%
Packaging
5g
Price
$294
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB29679
Product name
Boc-L-threonine dicyclohexylamine salt
Packaging
1g
Price
$340
Updated
2021/12/16
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BOC-THR-OH DCHA Chemical Properties,Usage,Production

Synthesis

28954-12-3

24424-99-5

2592-18-9

General procedure for the synthesis of (2S,3R)-2-((tert-butoxycarbonyl)amino)-3-hydroxybutyric acid from (2S,3S)-2-amino-3-hydroxybutyric acid and di-tert-butyl dicarbonate: 1. di-tert-butyl dicarbonate (550 mg, 2.52 mmol) was added to a mixture of (2S,3S)-2-amino-3-hydroxybutyric acid (250 mg, 2.10 mmol) and sodium bicarbonate (529 mg, 6.30 mmol) in methanol (2.5 mL) and water (2.5 mL) at 0 °C. 2. The reaction mixture was slowly warmed to room temperature and stirred at room temperature for 18 hours. 3. Upon completion of the reaction, the methanol was removed by concentration under reduced pressure. 4. The residual aqueous phase was adjusted to pH 3~4 with 6N hydrochloric acid solution and then extracted three times with ether. 5. The organic phases were combined, washed sequentially with water and saturated brine, and then dried with anhydrous sodium sulfate. 6. The desiccant was removed by filtration, and the filtrate was concentrated under reduced pressure and dried under vacuum for 24 h. (2S,3S)-2-((tert-butoxycarbonyl)amino)-3-hydroxybutyric acid (304 mg) was obtained as a white solid. 7. The retention time (Rt) was 0.36 min as analyzed by LCMS and mass spectrometry showed m/z 220 [M + H]+ and m/z 218 [M-H]-.

References

[1] Organic and Biomolecular Chemistry, 2018, vol. 16, # 38, p. 6935 - 6960
[2] Journal of the American Chemical Society, 2000, vol. 122, # 41, p. 10214 - 10215
[3] Journal of the American Chemical Society, 2003, vol. 125, # 7, p. 1877 - 1887
[4] Journal of Organic Chemistry, 1982, vol. 47, # 26, p. 5160 - 5167
[5] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 16, p. 4329 - 4332

BOC-THR-OH DCHA Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-THR-OH DCHA Suppliers

Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
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58
Aladdin Scientific
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Email
tp@aladdinsci.com
Country
United States
ProdList
52923
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58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
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58
Combi-Blocks Inc.
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sales@combi-blocks.com
Country
United States
ProdList
6618
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3B Scientific Corporation
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Email
sales@3bsc.com
Country
United States
ProdList
6962
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INDOFINE Chemical Company, Inc.
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Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
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3B Scientific Corporation
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Email
sales@3bsc.com
Country
United States
ProdList
6718
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Advanced ChemTech
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United States
ProdList
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View Lastest Price from BOC-THR-OH DCHA manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Boc-L-allo-Thr-OH 23082-30-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-11-21
Career Henan Chemical Co
Product
BOC-THR-OH DCHA 23082-30-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-16
Career Henan Chemical Co
Product
BOC-THR-OH DCHA 23082-30-6
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2018-08-15

23082-30-6, BOC-THR-OH DCHARelated Search:


  • N-ALPHA-T-BUTYLOXYCARBONYL-ALLO-L-THREONINE DICYCLOHEXYLAMINE
  • BOC-L-THREONINE DCHA
  • BOC-THR-OH DCHA
  • BOC-ALLO-THR-OH DCHA
  • BOC-L-ALLO-THR-OH DCHA
  • N-ALPHA-TERT-BUTYLOXYCARBONYL-ALLO-L-THREONINE DICYCLOHEXYLAMINE
  • Boc-allo-Thr-OH
  • (2S,3S)-2-((tert-Butoxycarbonyl)aMino)-3-hydroxybutanoic acid
  • N-Boc-L-Allothreonine
  • Boc-Allo-Thr.DCHA
  • N-tert-Butoxycarbonyl-L-allothreonine
  • BOC-L-allothreonine
  • Boc-L-allo-Thr-OH
  • L-Allothreonine, N-[(1,1-dimethylethoxy)carbonyl]-
  • N-Boc-(2S,3S)-2-amino-3-hydroxybutyric acid
  • Boc-L-allo-Thr-OH?DCHA, CAS 23082-30-6
  • 23082-30-6
  • C12H23NC9H17NO5
  • Amino Acids