BOC-L-Serine

Product Name: BOC-L-Serine
CAS No.: 3262-72-4
Chemical Name: BOC-L-Serine
Synonyms: Boc-Ser.H2O;Boc-Ser;BOC-L-SER;N-BOC-L-SERINE;BOC-L-SER-OH;221-867-3;BOC-SERINE;(R)-2-((tert-butoxycarbonyl)aMino)-3-hydroxypropanoic acid;BOC-L-SERINE;Boc-D-Ser.H2o
CBNumber: CB0668033
Molecular Formula: C8H15NO5
Formula Weight: 205.21
MOL File: 3262-72-4.mol

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BOC-L-Serine Property

Melting point:: 91 °C (dec.)(lit.)
alpha: -7.5 º (c=2, water)
Boiling point:: 385.1±37.0 °C(Predicted)
Density: 1.240±0.06 g/cm3(Predicted)
refractive index: -4 ° (C=1, AcOH)
storage temp.: 2-8°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka: 3.62±0.10(Predicted)
form: Powder
color: White
optical activity: [α]20/D 3.5±0.5°, c = 2% in acetic acid
Water Solubility: almost transparency
BRN: 2212252
Major Application: peptide synthesis
InChI: 1S/C8H15NO5/c1-8(2,3)14-7(13)9-5(4-10)6(11)12/h5,10H,4H2,1-3H3,(H,9,13)(H,11,12)/t5-/m0/s1
InChIKey: FHOAKXBXYSJBGX-YFKPBYRVSA-N
SMILES: CC(C)(C)OC(=O)N[C@@H](CO)C(O)=O
CAS DataBase Reference: 3262-72-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 24/25-36-26
WGK Germany: 3
HS Code: 29241990
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 15500
Product name: Boc-Ser-OH
Purity: ≥99.0% (T)
Packaging: 5g
Price: $38.9
Updated: 2026/03/19

Sigma-Aldrich

Product number: 8.53020
Product name: Boc-Ser-OH
Purity: Novabiochem?
Packaging: 25G
Price: $126
Updated: 2026/03/19

Sigma-Aldrich

Product number: 15500
Product name: Boc-Ser-OH
Purity: ≥99.0% (T)
Packaging: 25g
Price: $101
Updated: 2026/03/19

Sigma-Aldrich

Product number: 8.53020
Product name: Boc-Ser-OH
Purity: Novabiochem?
Packaging: 100G
Price: $386
Updated: 2025/07/31

TCI Chemical

Product number: B1637
Product name: N-(tert-Butoxycarbonyl)-L-serine
Purity: >97.0%(T)
Packaging: 5g
Price: $28
Updated: 2026/03/19

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BOC-L-Serine Chemical Properties,Usage,Production

Chemical Properties

white to light brown powder

Uses

Starting material for the synthesis of various a-amino acids via the b-lactone

Uses

Boc-Ser-OH may be used in the synthesis of the following:

2-(N-Fmoc)-3-(N-Boc-N-methoxy)-diaminopropanoic acid (Fmoc: 9-fluorenylmethoxycarbonyl; Boc: t-butyloxycarbonyl)
Boc-Ser-Leu-OMe
cyclic peptide synthesis
benzylsulfonyl-D-Ser-Ser-4-amidinobenzylamide

General Description

Boc-Ser-OH is an amino acid derivative.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

18.1g of L-serine, was added to 200m1 of 0.010mol/L sodium carbonate solution and dissolved with stirring, then 8g of (BoC)0 was added and reacted for 3 hours, then 8g of (BoC)0 was added and reacted for 5 hours, and finally 9g of (Boc)0 was added and reacted for 7 hours. The impurities were extracted three times with petroleum ether 10 ml/time. 3 mol/L hydrochloric acid was used to adjust the pH=3 and then the product was extracted three times with tetrahydrofuran 0.5 L/time. The ester layers were combined and washed with brine to neutral. Add 15 g of anhydrous sodium sulfate and dry for 8 hours. Filtration, filtrate concentrated dry under reduced pressure, add 50ml petroleum squint stirring crystallization. Centrifuge the product and dry. BOC-L-serine 23.1 g was obtained. yield 90.15%.

BOC-L-Serine Preparation Products And Raw materials

Raw materials

Preparation Products

N-BOC-O-Benzyl-L-serine

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BOC-L-Serine Suppliers

Americas 1 Belgium 1 China 321 Europe 4 France 2 Germany 8 Hungary 1 India 37 Japan 9 South Korea 1 Switzerland 5 United Kingdom 15 United States 54 Global 459

Shanghai Chiral Chemicals Inc.

Tel: 021-37285021 13472570865
Fax: 86-021-51714507
Email: tym7xi@aliyun.com
Country: China
ProdList: 297
Advantage: 64

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Sichuan Tongsheng Amino acids Co.,Ltd.

Tel: 0838-2274206 13908101207
Fax: +86-838-2274207
Email: sales@biots.cn
Country: China
ProdList: 278
Advantage: 66

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9416
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44802
Advantage: 61

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View Lastest Price from BOC-L-Serine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: BOC-L-Serine 3262-72-4
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 500kgs
Release date: 2021-09-23

Hebei Chuanghai Biotechnology Co., Ltd

Product: BOC-L-Serine 3262-72-4
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2024-10-24

Shaanxi Dideu Medichem Co. Ltd

Product: BOC-L-Serine 3262-72-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-11

3262-72-4, BOC-L-SerineRelated Search:

N-(tert-Butoxycarbonyl)-L-glutamine BOC-N-Methyl-L-alanine 3-FLUORO-5-(TRIFLUOROMETHYL)PHENOL Boc-O-tert-butyl-L-serine dicyclohexylamine salt BOC-L-Serine Boc-L-Threonine Boc-Thr(Bzl)-OH BOC-THR(ME)-OH BOC-L-SERINE BENZYL ESTER,N-BOC-L-SERINE,N-ALPHA-T-BOC-L-SERINE,BOC-SER-OH Boc-Ser(tBu)-OH BOC-L-SERINE-OH,BOC-L-SERINE MONOHYDRATE,BOC-L-SERINE H2O,BOC-L-SERINE HYDRATE,BOC-SER-OH H2O,BOC-SER-OH MONOHYDRATE Boc-D-Serine BOC-D-SERINE METHYL ESTER,N-BOC-D-serine methylester,BOC-D-SERINE METHYLESTER OIL Boc-D-Ser(Bzl)-OH 1-(4-Bromophenyl)ethanol BOC-L-SERINE(METHYL ETHER) Boc-L-serine methyl ester L-(+)-Prolinol

L-Serine, N-[(1,1-dimethylethoxy)carbonyl]- (9CI)

Boc-Ser-OH Synonyms:Boc-L-serine

N-ALPHA-T-BUTYLOXYCARBONYL-L-SERINE

BOC-L-PROLINOL LIQUID

N-[(1,1-DIMETHYLETHOXY)CARBONYL]- L-SERINE

N-Boc-L-serine, 98%(dry wt.), may cont. up to 10% water

BOC-L-SERINE extrapure

N-(tert-Butoxycarbonyl)-L-serine, Boc-L-serine

(2R)-3-Hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid

L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-

BOC-L-SERINE, TECH., HYDRATE, 93%

N-T-BOC-L-SERINE CRYSTALLINE

N-Boc-L-serine Boc-Ser-OH

2-(tert-butoxycarbonyl)-3-hydroxypropanoic acid

L-Serine-d3-N-t-BOC

Boc-L-serine, 99%, anhydrous

Boc-Ser.H2O

(R)-2-((tert-butoxycarbonyl)aMino)-3-hydroxypropanoic acid

Boc-D-Ser.H2o

N-Boc-L-Serine, 95+%

(R)-2-amino-3-(2-aminoethylamino)-1-propanol trihydrochloride

Boc-Ser-OH >=99.0% (T)

(Tert-Butoxy)Carbonyl Ser-OH (ee>99.4%, H2O <0.5%)

(S)-N-BOC-SERINE

(S)-Boc-2-amino-3-hydroxypropionic acid

Boc-L-serine≥ 98% (HPLC)

Boc-L-β-Hydroxyalanine

N-Boc-L-serine,99%e.e.

N-Boc-L-serine(contains ca. 10% H2O)

Boc-Ser

BOC-L-Serine hydrate, tech.

(S)-2-[(tert-Butyloxycarbonyl)amino]-3-hydroxypropionic acid

N-(tert-Butoxycarbonyl)serine

N-(tert-Butyloxycarbonyl)-L-serine

N-[(tert-Butyloxy)carbonyl]-L-serine

(2S)-2-[(tert-Butoxycarbonyl)amino]-3-hydroxypropanoic acid

Boc-Ser-OH·H2O Boc-L-Serine Monohydrate

BOC-L-Serine hydrate,93%,tech.

N-BOC-L-SERINE

N-ALPHA-T-BOC-L-SERINE

N-ALPHA-TERT-BUTYLOXYCARBONYL-L-SERINE

N-T-BUTOXYCARBONYL-L-SERINE

N-(TERT-BUTOXYCARBONYL)-L-SERINE

BOC-SERINE-OH

BOC-SERINE

BOC-L-SER-OH

BOC-L-SER

BOC-L-SERINE

(2S)-3-hydroxy-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]propanoate

N-(tert-Butoxycarbonyl)-L-serine &gt

221-867-3

(2S)-3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid

N-tert-Boc-L-serine

N-Boc-L-serine, 98%

Boc-Ser-OH 98%

3262-72-4

C8H15NO5

HOCH2CHCOOHNHCOOCCH33