1-Boc-piperidine

Product Name: 1-Boc-piperidine
CAS No.: 75844-69-8
Chemical Name: 1-Boc-piperidine
Synonyms: 1-BOC-PIPERIDINE;N-BOC-PIPERIDINE;1-Boc-Piperidine,98%;N-Boc-tetrahydropyridine;1-(tert-Butoxycarbonyl)piperidine;N-(TERT-BUTOXYCARBONYL)PIPERIDINE;tert-Butyl 1-piperidinecarboxylate;1-(tert-Butyloxycarbonyl)piperidine;tert-butyl piperidine-1-carboxylate;1-(tert-Butoxycarbonyl)piperidine >
CBNumber: CB7348312
Molecular Formula: C10H19NO2
Formula Weight: 185.26
MOL File: 75844-69-8.mol

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1-Boc-piperidine Property

Boiling point:: 130-140°C 15mm
Density: 0.964 g/mL at 25 °C(lit.)
refractive index: n20/D 1.454(lit.)
Flash point:: 188 °F
storage temp.: Sealed in dry,Room Temperature
form: Liquid
pka: -1.28±0.20(Predicted)
color: Clear colorless to pale yellow
BRN: 3604898
CAS DataBase Reference: 75844-69-8(CAS DataBase Reference)

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Safety

Hazard Codes: T,N,Xi
Risk Statements: 25-36/37/38-50
Safety Statements: 26-36-45-60-61
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 3
HazardClass: IRRITANT, KEEP COLD
PackingGroup: Ⅲ
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H227Combustible liquid

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H400Very toxic to aquatic life

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4625
Product name: 1-(tert-Butoxycarbonyl)piperidine
Purity: >98.0%(GC)
Packaging: 5g
Price: $43
Updated: 2025/07/31

TCI Chemical

Product number: B4625
Product name: 1-(tert-Butoxycarbonyl)piperidine
Purity: >98.0%(GC)
Packaging: 25g
Price: $142
Updated: 2025/07/31

TRC

Product number: B662033
Product name: 1-BOC-Piperidine
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB142536
Product name: tert-Butyl piperidine-1-carboxylate
Packaging: 10g
Price: $80
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-FU
Product name: tert-Butyl piperidine-1-carboxylate
Packaging: 5G
Price: $75
Updated: 2021/12/16

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1-Boc-piperidine Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Synthesis

110-89-4

24424-99-5

75844-69-8

The general procedure for the synthesis of tert-butyl piperidine-1-carboxylate from hexahydropyridine and di-tert-butyl dicarbonate is as follows: hexahydropyridine (1 mmol) was added to a solution of ethanol (1 mL) containing magnetically stirred guanidine hydrochloride (15 mol%) and di-tert-butyl dicarbonate (1.2 mmol) and the reaction was stirred to completion at 35-40 °C (reaction progress was monitored by TLC or GC). Upon completion of the reaction, the ethanol is evaporated under vacuum and the residue is washed with water to remove the catalyst or dissolved in dichloromethane (or ethyl acetate) and filtered to separate the catalyst. If an organic solvent is used for post-treatment, the product is almost pure after evaporation of the organic solvent. If excess di-tert-butyl dicarbonate is used, the product can be washed with petroleum ether or hexane to recover the residual di-tert-butyl dicarbonate. If necessary, the product can be further purified by crystallization (using hexane and dichloromethane, or ether and petroleum ether as solvents) or silica gel column chromatography (ethyl acetate-hexane (1:6) as eluent).

References

[1] Synthesis, 2006, # 16, p. 2784 - 2788
[2] Tetrahedron Letters, 2007, vol. 48, # 47, p. 8318 - 8322
[3] Tetrahedron Letters, 2008, vol. 49, # 16, p. 2527 - 2532
[4] Tetrahedron Letters, 2011, vol. 52, # 12, p. 1260 - 1264
[5] Monatshefte fur Chemie, 2011, vol. 142, # 10, p. 1035 - 1043

1-Boc-piperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Boc-piperidine Suppliers

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View Lastest Price from 1-Boc-piperidine manufacturers

Career Henan Chemical Co

Product: 1-Boc-piperidine 75844-69-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-02

75844-69-8, 1-Boc-piperidineRelated Search:

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1-(tert-Butoxycarbonyl)piperidine

1-Boc-Piperidine,98%

tert-Butyl 1-piperidinecarboxylate

1-(<i>tert</i>-Butoxycarbonyl)piperidine

1-BOC-PIPERIDINE

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75844-69-8

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