ChemicalBook > CAS DataBase List > 2-Methoxycarbonylphenylboronic acid

2-Methoxycarbonylphenylboronic acid

Product Name
2-Methoxycarbonylphenylboronic acid
CAS No.
374538-03-1
Chemical Name
2-Methoxycarbonylphenylboronic acid
Synonyms
Bm199;METHYL 2-BORONOBENZOATE;1-Methyl 2-boronobenzoate;Chemical Formula: C18H19BO6;2-(Methoxycarbonyl)Phenylboron;2-Carbomethoxybenzeneboronicacid;2-Methoxycarbonylphenylboronicaci;2-(methoxylated)benzylboronic acid;2-METHOXYCARBONYLPHENYLBORONIC ACID;Benzoicacid,2-borono-,1-methylester
CBNumber
CB7349102
Molecular Formula
C8H9BO4
Formula Weight
179.97
MOL File
374538-03-1.mol
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2-Methoxycarbonylphenylboronic acid Property

Melting point:
90-96°C
Boiling point:
359.0±44.0 °C(Predicted)
Density 
1.25±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
soluble in Methanol
pka
8.19±0.58(Predicted)
form 
Crystalline Powder
color 
White
BRN 
8313459
CAS DataBase Reference
374538-03-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
TSCA 
No
HazardClass 
IRRITANT
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
683809
Product name
2-Methoxycarbonylphenylboronic acid
Purity
≥95.0%
Packaging
5g
Price
$108
Updated
2025/07/31
Sigma-Aldrich
Product number
683809
Product name
2-Methoxycarbonylphenylboronic acid
Purity
≥95.0%
Packaging
1g
Price
$32
Updated
2023/06/20
TCI Chemical
Product number
M1905
Product name
2-(Methoxycarbonyl)phenylboronic Acid (contains varying amounts of Anhydride)
Packaging
1g
Price
$27
Updated
2025/07/31
TCI Chemical
Product number
M1905
Product name
2-(Methoxycarbonyl)phenylboronic Acid (contains varying amounts of Anhydride)
Packaging
5g
Price
$68
Updated
2025/07/31
TRC
Product number
M329683
Product name
2-Methoxycarbonylphenylboronic acid
Packaging
100mg
Price
$45
Updated
2021/12/16
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2-Methoxycarbonylphenylboronic acid Chemical Properties,Usage,Production

Chemical Properties

White to brown powder

Uses

2-Methoxycarbonylphenylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

General Description

May contain varying amounts of anhydride

Synthesis

67-56-1

149105-19-1

374538-03-1

In a 20 L autoclave, 7.5 g of anhydrous methanol and 1.66 Kg (10 mol) of 2-carboxyphenylboronic acid were added and stirring was initiated to mix the reactants. The temperature of the reaction kettle was slowly raised to 40 °C and maintained in the range of 40 to 55 °C. Subsequently, thionyl chloride (1.31 Kg, 11 mol) was slowly added dropwise to the reaction kettle, and after the dropwise addition was completed, the temperature was raised to reflux condition and the reaction was continued for 2-3 hours. The completion of the reaction was confirmed by thin layer chromatography (TLC, unfolding agent ratio of n-heptane: ethyl acetate = 2:1). Upon completion of the reaction, the reaction solution was cooled and subsequently subjected to reduced pressure distillation to remove the solvent. The residue was cooled to -10°C to 10°C and stirred at this temperature for 1 hour. Next, the drying process was stopped by filtration under reduced pressure at 80 °C until no impurities were confirmed to be present by hydrogen nuclear magnetic resonance (HNMR, observing the peak at 3.21 ppm with DMSO-d6 as solvent). Finally, the mixture was stirred at room temperature, filtered and dried at room temperature to give 1.74 Kg of the white solid product 2-(methoxycarbonyl)phenylboronic acid in 96.7% yield with 19.8% water and 140.5% Karl Fischer moisture.

References

[1] Patent: CN106188117, 2016, A. Location in patent: Paragraph 0014

2-Methoxycarbonylphenylboronic acid Preparation Products And Raw materials

Raw materials

Bis(2-dimethylaminoethyl) ether Methyl 2-iodobenzoate Tetrahydrofuran Triisopropyl borate Magnesium

Preparation Products

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View Lastest Price from 2-Methoxycarbonylphenylboronic acid manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.
Product
2-Methoxycarbonylphenylboronic acid 374538-03-1
Price
US $0.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
20tons
Release date
2025-09-18
Hebei Zhuanglai Chemical Trading Co Ltd
Product
2-Methoxycarbonylphenylboronic acid 374538-03-1
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-02
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Methoxycarbonylphenylboronic acid 374538-03-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

374538-03-1, 2-Methoxycarbonylphenylboronic acidRelated Search:

m-Anisyl alcohol Phenylboronic acid (4-METHOXYPHENYL)-BORANE Glycine (Trifluoromethoxy)benzene 4-Methoxyphenylboronic acid 3-Methoxybenzaldehyde Anisole 4-Methoxybenzoic acid Ethyl 2-(Chlorosulfonyl)acetate Folic acid 4-Methoxybenzyl cyanide o-Anisaldehyde p-Anisaldehyde 4-Methoxyphenylacetic acid 5-FLUORO-2-METHOXYCARBONYLPHENYLBORONIC ACID 2-METHOXY-5-METHOXYCARBONYLPHENYLBORONIC ACID, PINACOL ESTER 2-Ethoxycarbonylbenzeneboronic acid

  • METHYL 2-BORONOBENZOATE
  • 2-(METHOXYCARBONYL)BENZENEBORONIC ACID
  • 2-METHOXYCARBONYLPHENYLBORONIC ACID
  • O-(METHOXYCARBONYL)PHENYLBORONIC ACID
  • Benzoic acid, 2-borono-, 1-methyl ester (9CI)
  • 2-Carbomethoxybenzeneboronicacid
  • 2-(Methoxycarbonyl)Phenylboron
  • 2-(Methoxycarbonyl)phenylboronic Acid (contains varying amounts of Anhydride)
  • 2-Methoxycarbonylphenylboronic acid ,97%
  • Bm199
  • 2-Methoxycarbonylphenylboronic acid (2-Methoxycarbonylphenyl)boronic acid
  • Chemical Formula: C18H19BO6
  • Benzoic acid, 2-borono-, methyl ester
  • Benzoicacid,2-borono-,1-methylester
  • 2-Methoxycarbonylphenylboronicaci
  • 1-Methyl 2-boronobenzoate
  • (2-(methoxycarbamoyl)phenyl)boronic acid
  • 2-(methoxylated)benzylboronic acid
  • 374538-03-1
  • CH3O2CC6H4BOH2
  • C8H9O4B
  • BORONIC ACID
  • Aryl Boronic Acids
  • Boronic Acids and Derivatives
  • Chemical Synthesis
  • Monosubstituted Aryl Boronic Acids
  • Organometallic Reagents
  • Boronate Ester
  • Boronic Acid
  • Potassium Trifluoroborate
  • blocks
  • BoronicAcids
  • Carboxes
  • Boronic acids
  • BORONICACID
  • B (Classes of Boron Compounds)
  • Aryl
  • Boronic Acids
  • Boronic Acids and Derivatives