4,5-Dimethoxy-2-nitrobenzoic acid
- Product Name
- 4,5-Dimethoxy-2-nitrobenzoic acid
- CAS No.
- 4998-07-6
- Chemical Name
- 4,5-Dimethoxy-2-nitrobenzoic acid
- Synonyms
- 6-NITROVERATRIC ACID;4-Nitroveratic acid;RARECHEM AL BO 1523;6-Nitroveratriceacid;4,5-Dimethoxy-2-nitr;6-Nitroveratricacid,99%;6-NITROVERATRIC ACID 99%;4,5-Dimethoxy-2-nitrobenzoic;4,5-dimethoxy-2-nitrobenzoate;3,4-DIMETHOXY-6-NITROBENZOIC ACID
- CBNumber
- CB7364668
- Molecular Formula
- C9H9NO6
- Formula Weight
- 227.17
- MOL File
- 4998-07-6.mol
4,5-Dimethoxy-2-nitrobenzoic acid Property
- Melting point:
- 195-197 °C(lit.)
- Boiling point:
- 368.87°C (rough estimate)
- Density
- 1.4777 (rough estimate)
- refractive index
- 1.5800 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Crystalline Powder
- pka
- 2.34±0.25(Predicted)
- color
- Yellow
- Water Solubility
- Insoluble in water. Soluble in DMSO and methanol. Solubility in hot 1mol/L NaOH (almost transparency).
- BRN
- 2123903
- InChI
- InChI=1S/C9H9NO6/c1-15-7-3-5(9(11)12)6(10(13)14)4-8(7)16-2/h3-4H,1-2H3,(H,11,12)
- InChIKey
- WWCMFGBGMJAJRX-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC(OC)=C(OC)C=C1[N+]([O-])=O
- CAS DataBase Reference
- 4998-07-6(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 329231
- Product name
- 4,5-Dimethoxy-2-nitrobenzoic acid
- Purity
- 99%
- Packaging
- 5g
- Price
- $67.1
- Updated
- 2023/06/20
- Product number
- D2628
- Product name
- 4,5-Dimethoxy-2-nitrobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $51
- Updated
- 2024/03/01
- Product number
- D2628
- Product name
- 4,5-Dimethoxy-2-nitrobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $157
- Updated
- 2024/03/01
- Product number
- L08510
- Product name
- 4,5-Dimethoxy-2-nitrobenzoic acid, 98%
- Packaging
- 5g
- Price
- $22.65
- Updated
- 2024/03/01
- Product number
- L08510
- Product name
- 4,5-Dimethoxy-2-nitrobenzoic acid, 98%
- Packaging
- 25g
- Price
- $61.65
- Updated
- 2024/03/01
4,5-Dimethoxy-2-nitrobenzoic acid Chemical Properties,Usage,Production
Chemical Properties
Yellow crystalline powder
Uses
4,5-Dimethoxy-2-nitrobenzoic acid was used in the synthesis of 4,5-dimethoxy-2-nitrobenzamide and 6,7-dimethoxyquinazoline derivatives.
Application
4,5-dimethoxy-2-nitrobenzoic acid in the reaction with organotin oxides/halides yields the organotin carboxylates in anhydrous toluene. The resulting triorganotin carboxylates are one-dimensional polymers that are solid with trigonal bipyramidal geometry, while in solution, they are tetrahedral. Reaction of di-n-butyl tin oxide with 4,5-dimethoxy-2-nitrobenzoic acid yields Tetrabutylbis(4,5-dimethoxy-2-nitro benzoate)Distannoxane Dimer crystallizes as the usual dicarboxylatotetraorganodistannoxane dimer[1-2].
General Description
4,5-Dimethoxy-2-nitrobenzoic acid is a nitroaromatic compound.
Synthesis
In 3,4-dimethoxy-6-nitrobenzaldehyde (10 g)The reaction medium (20 mL of water, 30 mL of methanol)Acetic acid (3.5 mL), 30% hydrogen peroxide (9 mL)Stir well and add sodium chlorite (content 80%, 9g) in water (5mL); Stirring warming to about 50, monitoring the reaction, After the reaction was completed, sodium bisulfite (10.5 g) was added to quench the reaction, The solvent was evaporated to dryness, the product was dissolved in a solution of sodium hydroxide (6g × 10mL)Filtered to remove impurities, the filtrate was added sulfuric acid to pH 1 precipitated product, Filter and dry and obtained product 4,5-Dimethoxy-2-nitrobenzoic acid 10g (93% yield, high-performance liquid chromatography 99.5% purity).
References
[1] Farooq Ali Shah. “Synthesis, Characterization and Crystal Structure of Tetrabutylbis(4,5-dimethoxy-2-nitro benzoato)Distannoxane Dimer.” Journal of Chemical Crystallography 41 9 (2011).
[2] F. A. Shah. “Organotin(IV) complexes of 4,5-dimethoxy-2-nitrobenzoic acid: Synthesis, characterization, and biological activity.” Russian Journal of Coordination Chemistry 35 12 (2009).
4,5-Dimethoxy-2-nitrobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
4,5-Dimethoxy-2-nitrobenzoic acid Suppliers
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View Lastest Price from 4,5-Dimethoxy-2-nitrobenzoic acid manufacturers
- Product
- 4,5-Dimethoxy-2-nitrobenzoic acid 4998-07-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 1000kg
- Release date
- 2023-10-11
- Product
- 4,5-Dimethoxy-2-nitrobenzoic acid 4998-07-6
- Price
- US $8.00-0.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 4,5-Dimethoxy-2-nitrobenzoic acid 4998-07-6
- Price
- US $0.00/KG
- Min. Order
- 25KG
- Purity
- 99.5%
- Supply Ability
- 3T/th
- Release date
- 2023-02-09