TRIMETHYLSILYL ISOCYANATE Property

Melting point:

-49°C

Boiling point:

90-92 °C(lit.)

Density 

0.851 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.396(lit.)

Flash point:

-2 °C

storage temp. 

2-8°C

solubility 

Miscible with ethers and o-dichlorobenzene.

form 

clear liquid

color 

Colorless to Almost colorless

Specific Gravity

0.867

Sensitive 

Moisture Sensitive

Hydrolytic Sensitivity

8: reacts rapidly with moisture, water, protic solvents

BRN 

1744962

CAS DataBase Reference

1118-02-1(CAS DataBase Reference)

EPA Substance Registry System

Isocyanatotrimethylsilane (1118-02-1)

Safety

Hazard Codes 

F,T

Risk Statements 

11-23-36/37-42

Safety Statements 

23-26-36/37/39-45

RIDADR 

UN 2478 3/PG 2

WGK Germany 

3

F 

10-19-21

TSCA 

Yes

HazardClass 

3

PackingGroup 

II

HS Code 

29319090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H331Toxic if inhaled

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

TRIMETHYLSILYL ISOCYANATE Chemical Properties,Usage,Production

Chemical Properties

Clear colorless liquid

Uses

Trimethylsilyl isocyanate is used in the preparation of 1-unsubstituted 4-(dialkylamino) imidazolin-2-ones. It finds application in the carbamoylation of aromatic hydrocarbons and alcohols. It is also used in the preparation of primary amides from Grignard reagents. Further, it is used in the synthesis of cyclic imides. It is also utilized for the synthesis of trifluoroacetyl isocyanate and cyclic imides. In addition to this, it is employed in the conversion of isocyanates to carbodiimides using cyclopentadienyl Mn(CO)3 catalysis.

Purification Methods

Purify it by repeated fractionation as for the isothiocyanate. [Eaborn J Chem Soc 3077 1950, Beilstein 4 III 1861, 4 IV 4011.]