7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE

Product Name: 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE
CAS No.: 31169-27-4
Chemical Name: 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE
Synonyms: KML-53;KML-22;CML-007;7-Bromo-4-chlorothieno[3,...;7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE;Thieno[3,2-d]pyrimidine,7-bromo-4-chloro-;7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE 96%;7-bromo-4-chlorothienol [3, 2-d] pyrimidine;7-Bromo-4-chloro-1,2-dihydro-thieno[3,2-d]pyrimidine;7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE ISO 9001：2015 REACH
CBNumber: CB7404078
Molecular Formula: C6H2BrClN2S
Formula Weight: 249.52
MOL File: 31169-27-4.mol

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7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE Property

Boiling point:: 345.5±37.0 °C(Predicted)
Density: 1.955±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: -0.77±0.40(Predicted)
Appearance: Off-white to yellow Solid

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN2811
HazardClass: IRRITANT
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B684903
Product name: 7-Bromo-4-chlorothieno[3,2-d]pyrimidine
Packaging: 2.5g
Price: $240
Updated: 2021/12/16

Apolloscientific

Product number: OR960451
Product name: 7-Bromo-4-chlorothieno[3,2-d]pyrimidine
Purity: 97%
Packaging: 1g
Price: $66
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB139925
Product name: 7-Bromo-4-chlorothieno[3,2-d]pyrimidine
Packaging: 500mg
Price: $80
Updated: 2021/12/16

AK Scientific

Product number: W5327
Product name: 7-Bromo-4-chlorothieno[3,2-d]pyrimidine
Packaging: 250mg
Price: $89
Updated: 2021/12/16

SynQuest Laboratories

Product number: 7H70-D-04
Product name: 7-Bromo-4-chlorothieno[3,2-d]pyrimidine
Packaging: 1g
Price: $125
Updated: 2021/12/16

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7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE Chemical Properties,Usage,Production

Synthesis

31169-25-2

31169-27-4

General procedure for the synthesis of 7-bromo-4-chlorothieno[3,2-d]pyrimidines from 7-bromothieno[3,2-D]pyrimidin-4(1H)-ones: 7-bromo-3H-thieno[3,2-d]pyrimidin-4-one (191, 153.0 mg, 0.66 mmol) was dissolved in phosphorochloridic acid (2 mL) and refluxed under nitrogen protection for 2 hours. After completion of the reaction, the reaction solution was cooled to room temperature and slowly poured into saturated aqueous sodium carbonate solution for neutralization. Subsequently, the aqueous phase mixture was extracted with ethyl acetate and the organic phase was washed sequentially with water and brine and dried with anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure and the residue was dried under vacuum overnight in the presence of phosphorus pentoxide to afford 7-bromo-4-chlorothieno[3,2-d]pyrimidine (192, 156.0 mg, 95% yield, white solid).

References

[1] Patent: US2006/4002, 2006, A1. Location in patent: Page/Page column 39
[2] Patent: WO2014/3483, 2014, A1. Location in patent: Page/Page column 19
[3] Patent: US2014/371219, 2014, A1. Location in patent: Paragraph 0206; 0207
[4] Patent: WO2012/93809, 2012, A2. Location in patent: Page/Page column 23
[5] Patent: US2013/274268, 2013, A1. Location in patent: Paragraph 0174-0175

7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE Suppliers

China 135 Germany 1 India 1 United Kingdom 1 United States 14 Global 152

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shangchem Co., Ltd.

Tel: +86-21-68182121
Fax: +86-21-68182121
Country: China
ProdList: 882
Advantage: 52

Pure Chemistry Scientific Inc.

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Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
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EnciPharmatech Co., Ltd

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Fax: 86 025 52714266
Email: stephen_shengll@hotmail.com
Country: China
ProdList: 232
Advantage: 64

SpringPharma Tech Co.,Ltd

Tel: +86-25-68710855, +86-25-68710897
Fax: 025-68710856
Email: sales@springpharma.net
Country: China
ProdList: 1261
Advantage: 62

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Aemon Chemical

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Email: acinfo@aemonchem.com
Country: China
ProdList: 1931
Advantage: 57

Hangzhou Yuhao Chemical Technology Co., Ltd

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Email: info@yuhaochemical.com
Country: China
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Advantage: 52

Heterochem

Tel: 027-88041443 13072715837
Fax: 027-51829379
Email: sales@hetero-chem.com
Country: China
ProdList: 696
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Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

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View Lastest Price from 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 7-Bromo-4-chlorothieno[3,2-d]pyrimidine 31169-27-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-22

Dideu Industries Group Limited

Product: 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE 31169-27-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-01

Zhuozhou Wenxi import and Export Co., Ltd

Product: Thieno[3,2-d]pyrimidine,7-bromo-4-chloro- 31169-27-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

31169-27-4, 7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINERelated Search:

7-Bromo-5H-pyrrolo[3,2-d]pyrimidin-4-amine 7-Bromoquinolin-3-ol 7-BROMO-3-CHLORO-1H-INDAZOLE 7-Bromo-3H-imidazo[4,5-b]... 7-BROMO-1H-INDOLE-3-CARBALDEHYDE 7-BroMo-quinoline-3-carbonitrile 7-BROMO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE 7-bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine 7-Bromo-3,4-dihydro-2H-benzo[1,4]oxazine 7-BroMo-3-Methyl-1H-indaz... 7-BroMo-1h-pyrrolo[3,2-b]pyridine 7-Bromo-3-methoxyquinoline 7-BROMO-1H-INDOLE-3-CARBOXYLIC ACID Tiotropium bromide 7-BroMo-5H-pyrrolo[3,2-d]pyriMidine 4-Chlorothieno[3,2-d]pyrimidine 6-BROMO-4-CHLOROTHIENO[2,3-D]PYRIMIDINE 6-bromo-4-chlorothieno[3,2-d]pyrimidine

7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE

CML-007

7-Bromo-4-chlorothieno[3,...

Thieno[3,2-d]pyrimidine,7-bromo-4-chloro-

7-Bromo-4-chloro-1,2-dihydro-thieno[3,2-d]pyrimidine

7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE ISO 9001：2015 REACH

KML-22

KML-53

7-bromo-4-chlorothienol [3, 2-d] pyrimidine

7-BROMO-4-CHLOROTHIENO[3,2-D]PYRIMIDINE 96%

31169-27-4

C6H2BrClN2S

Heterocycle-Pyrimidine series

CHIRAL CHEMICALS