ChemicalBook > CAS DataBase List > Eltanolone
Eltanolone
- Product Name
- Eltanolone
- CAS No.
- 128-20-1
- Chemical Name
- Eltanolone
- Synonyms
- SKF 6455;Kabi2213;NSC 82867;Kabi 2213;Kabi-2213;ELTANOLONE;PREGNANOLONE;Pregnanolone II;EPIPREGNANOLONE;3α,5β-Pregnanolone
- CBNumber
- CB7407837
- Molecular Formula
- C21H34O2
- Formula Weight
- 318.49
- MOL File
- 128-20-1.mol
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Eltanolone Property
- Melting point:
- 149°C
- alpha
- D23 +59.6° (c = 0.3 in chloroform); D26 +108.5 ±1° (c = 9.23 mg/1.23 ml abs ethanol)
- Boiling point:
- 397.64°C (rough estimate)
- Density
- 1.0234 (rough estimate)
- refractive index
- 1.5344 (estimate)
- storage temp.
- Store at RT
- solubility
- Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
- pka
- 15.12±0.70(Predicted)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 8mg/L(room temperature)
- NIST Chemistry Reference
- 3Alpha-hydroxy-5beta-pregnan-20-one(128-20-1)
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- P8129
- Product name
- 5β-Pregnan-3α-ol-20-one
- Packaging
- 25mg
- Price
- $313
- Updated
- 2024/03/01
TRC
- Product number
- P711300
- Product name
- 5β-Pregnan-3α-ol-20-one
- Packaging
- 25mg
- Price
- $430
- Updated
- 2021/12/16
TRC
- Product number
- P711300
- Product name
- 5β-Pregnan-3α-ol-20-one
- Packaging
- 10mg
- Price
- $185
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B7455
- Product name
- 1-((3R,5R,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone
- Packaging
- 50mg
- Price
- $223
- Updated
- 2021/12/16
IsoSciences
- Product number
- 13398
- Product name
- Pregnanolone
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $239
- Updated
- 2021/12/16
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Eltanolone Chemical Properties,Usage,Production
Uses
A hyponotic-anaesthetic agent.
Definition
ChEBI: The 3alpha-stereoisomer of 3-hydroxy-5beta-pregnan-20-one.
Biological Activity
GABA A receptor positive allosteric modulator. Neuroactive steroid.
Biochem/physiol Actions
5β-Pregnan-3α-ol-20-one or pregnanolone is a neurosteroid that acts as a positive allosteric modulator (PAMs) of γ-aminobutyric acid A receptors (GABAARs). It mediates anti-convulsive, anxiolytic and sedative effects. Pregnanolone inhibits γ-aminobutyric acid C receptor (GABAC) receptor-based response and favors GABAA?receptor-mediated currents.
storage
Store at RT
Eltanolone Preparation Products And Raw materials
Raw materials
Preparation Products
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