ChemicalBook > CAS DataBase List > N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride

N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride

Product Name
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride
CAS No.
637-01-4
Chemical Name
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride
Synonyms
TMPD;TMPD (hydrochloride);N,N,N';WURSTER-REAGENT;WURSTER'S REAGENT;TMPD DIHYDROCHLORIDE;Wurster's Blue dihydrochloride;TetramethylPPhenylenediamineDihcl;WURSTER'S REAGENT DIHYDROCHLORIDE;N,NnTetramethyl-P-Phenylenediamine
CBNumber
CB7432725
Molecular Formula
C10H17ClN2
Formula Weight
200.71
MOL File
637-01-4.mol
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N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride Property

Melting point:
222-224 °C(lit.)
Boiling point:
378.54°C (rough estimate)
Density 
1.1961 (rough estimate)
refractive index 
1.6400 (estimate)
storage temp. 
room temp
solubility 
H2O: soluble500mg/10 mL
form 
powder
color 
off-white to gray
Water Solubility 
SOLUBLE
Sensitive 
Light Sensitive
BRN 
5132096
Stability:
Stable. Incompatible with strong oxidizing agents, strong bases.
CAS DataBase Reference
637-01-4(CAS DataBase Reference)
EPA Substance Registry System
1,4-Benzenediamine, N,N,N',N'-tetramethyl-, dihydrochloride (637-01-4)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22-40
Safety Statements 
26-36-36/37-22-36/37/39
RIDADR 
2811
WGK Germany 
3
F 
8
TSCA 
Yes
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
29215190
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
87890
Product name
N,N,N′,N′-Tetramethyl-p-phenylenediamine dihydrochloride
Purity
≥97.0% (AT)
Packaging
5g
Price
$58.7
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21102
Product name
N,N,N′,N′-Tetramethyl-1,4-phenylenediammonium dichloride
Purity
for synthesis
Packaging
2g
Price
$79.3
Updated
2024/03/01
Sigma-Aldrich
Product number
87890
Product name
N,N,N′,N′-Tetramethyl-p-phenylenediamine dihydrochloride
Purity
≥97.0% (AT)
Packaging
25g
Price
$140
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21102
Product name
N,N,N′,N′-Tetramethyl-1,4-phenylenediammonium dichloride
Purity
for synthesis
Packaging
10g
Price
$152
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21102
Product name
N,N,N′,N′-Tetramethyl-1,4-phenylenediammonium dichloride
Purity
for synthesis
Packaging
25g
Price
$366
Updated
2024/03/01
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N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride Chemical Properties,Usage,Production

Chemical Properties

Off white to gray powder

Uses

N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is an oxidizable compound that serves as a reducing co-substrate for heme peroxidases. It is also used as a test reagent in microbiology for the classification of cytochrome oxidase positive aerobic microorganisms. It finds application as a detection of peroxidases on polyacrylamide gels.

Uses

N,N,N′,N′-Tetramethyl-p-phenylenediamine dihydrochloride has been used to determine the oxidase activity displayed by various microorganisms.

General Description

N,N,N′,N′-Tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is a redox mediator used in the oxidase test for detecting bacterial cytochrome c oxidases. TMPD is commonly used to perform the oxidase test for the colorimetric identification of pathogenic and non-pathogenic bacteria.

Purification Methods

Crystallise the salt from isopropyl or n-butyl alcohols, saturated with HCl. Treat it with aqueous NaOH to give the free base (see previous entry) which is filtered, dried and sublimed in a vacuum. [Guarr et al. J Am Chem Soc 107 5104 1985, Beilstein 13 H 74.]

N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride Preparation Products And Raw materials

Raw materials

Acetone Sodium bromide Calcium chloride Sodium chloride p-Phenylenediamine dihydrochloride Copper(I) chloride Methanol Sulfuric acid

Preparation Products

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N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride Suppliers

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View Lastest Price from N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride 637-01-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-28
Hebei Mojin Biotechnology Co., Ltd
Product
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride 637-01-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-10-27
Henan Aochuang Chemical Co.,Ltd.
Product
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride 637-01-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-23

637-01-4, N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochlorideRelated Search:

N,N-Dimethyl-1,4-phenylenediamine Cysteamine hydrochloride 1-Methylpyrrolidine o-Phenylenediamine LITHIUM PERIODATE Benzhydrylamine 2-Phenylethylamine hydrochloride Burgess reagent p-Phenylenediamine BLOCKING REAGENT GE N-Methyl-2-pyrrolidone Methoxyammonium chloride 2,3,5,6-TETRAMETHYL-1,4-PHENYLENEDIAMINE 1-Methylimidazole 2-Aminoethylammonium chloride p-Phenylenediamine dihydrochloride Dihydrochloride Hexamethylenetetramine

  • N,N,N'
  • N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride;NNN'N'-Tetramethyl-p-phenylene-diamine dihydrochloride
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  • N,N,N',N'-TETRAMETHYL-P-PHENYLENEDIAMINE DI HCL
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  • N,N,N',N'-TETRAMETHYL-4-PHENYLENEDIAMINE DIHYDROCHLORIDE
  • TMPD DIHYDROCHLORIDE
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  • n,n,ni,ni-tetramethyl-p-phenylenediaminedihydrochloride
  • N,N,N'',N''-Tetramethyl-p-phenylenediamine hydrochloride
  • N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%
  • N,NnTetramethyl-P-Phenylenediamine
  • N,N,N',N'-Tetramethyl-1,4-phenylenediamine·2hydrochloride
  • tetramethyl-p-phenylenediamine dihydrochloride
  • N,N,N',N'-TetraMethyl-p-phenylenediaMine dihydrochloride >=97.0% (AT)
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  • N,N,N',N'-TETRAMETHYL-1,4-PHENYLENEDIAMM
  • N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride ISO 9001：2015 REACH
  • 637-01-4 N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride C10H18Cl2N2
  • N,N,N,N-Tetramethyl-p-phenylenediamine Dihydrochloride (Wursters Reagent, TMPPD) extrapure AR, 99%
  • N,N,N‘,N’-TETRAMETHYL-p-PHENYLENEDIAMINE DIHYDROCHLORIDE Extra Pure
  • 1,4-Benzenediamine,N1,N1,N4,N4-tetramethyl-, hydrochloride (1:2)
  • N,N,N',N'-Tetramethyl-p-phenylenediam
  • N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride
  • N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride (TMPD)
  • TMPDN,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride
  • 637-01-4
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