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Isocoptisine acetate

Product Name
Isocoptisine acetate
CAS No.
30426-66-5
Chemical Name
Isocoptisine acetate
Synonyms
Isocoptisine acetate;Pseudocoptisine acetate
CBNumber
CB74806614
Molecular Formula
C21H17NO6
Formula Weight
379.37
MOL File
30426-66-5.mol
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Isocoptisine acetate Property

Melting point:
146-147 °C
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0100505
Product name
Pseudocoptisine(acetate)
Packaging
1mg
Price
$724
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594453
Product name
Isocoptisine acetate
Packaging
5mg
Price
$1356.6
Updated
2021/12/16
ChemScene
Product number
CS-0100505
Product name
Pseudocoptisine(acetate)
Packaging
5mg
Price
$2171
Updated
2021/12/16
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Isocoptisine acetate Chemical Properties,Usage,Production

Uses

Pseudocoptisine (Isocoptisine) acetate is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine acetate inhibits acetylcholinesterase (AChE) activity with an IC50 of 12.8 μM. Anti-inflammatory and anti-amnestic effects[1][2].

in vivo

The anti-amnesic activities of Pseudocoptisine in mice on the learning and memory impairments induced by scopolamine (1.0 mg/kg, i.p.) are examined. Pseudocoptisine (2.0 mg/kg, p.o.) significantly reverses cognitive impairments in mice by passive avoidance test[1].

References

[1] Hung TM, et al. Anti-amnestic activity of pseudocoptisine from Corydalis Tuber. Biol Pharm Bull. 2008;31(1):159-162. DOI:10.1248/bpb.31.159
[2] Yun KJ, et al. Quaternary alkaloid, pseudocoptisine isolated from tubers of Corydalis turtschaninovi inhibits LPS-induced nitric oxide, PGE(2), and pro-inflammatory cytokines production via the down-regulation of NF-kappaB in RAW 264.7 murine macrophage c DOI:10.1016/j.intimp.2009.08.001

Isocoptisine acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Isocoptisine acetate Suppliers

Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
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+86-28-82633165
Email
cwb1@biopurify.cn
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China
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2376
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60
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
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32435
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58
Chengdu Peter-like Biotechnology Co., Ltd.
Tel
18108052721
Email
2850505130@qq.com
Country
China
ProdList
5167
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Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
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58
Naturewill Biotechnology Co., Ltd.
Tel
028-82632533 18113192475
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3157321941@qq.com
Country
China
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4993
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58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
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9835
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58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29257
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58
Mensura Group Limited
Tel
17318633522
Fax
028-87362290
Email
18109034517@163.com
Country
China
ProdList
2898
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58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
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58