Thymopentin

Product Name: Thymopentin
CAS No.: 69558-55-0
Chemical Name: Thymopentin
Synonyms: TP-5;RKDVY;Immunox;Timunox;ORF-15244;Thyopentin;THYMOPETIN;THYMOPENTIN;Thymopentine;ThymopentinⅡ
CBNumber: CB7491069
Molecular Formula: C30H49N9O9
Formula Weight: 679.77
MOL File: 69558-55-0.mol

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Thymopentin Property

Density: 1.44±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml
pka: 3.07±0.10(Predicted)
form: Powder
color: White
CAS DataBase Reference: 69558-55-0(CAS DataBase Reference)

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Safety

WGK Germany: 3
HS Code: 3504009000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T8806
Product name: Thymopentin
Purity: ≥97% (HPLC)
Packaging: 10mg
Price: $235
Updated: 2024/03/01

Alfa Aesar

Product number: J61431
Product name: Thymopentin
Purity: 99+%
Packaging: 25mg
Price: $117
Updated: 2023/06/20

Alfa Aesar

Product number: J61431
Product name: Thymopentin
Purity: 99+%
Packaging: 100mg
Price: $257
Updated: 2021/12/16

Cayman Chemical

Product number: 30119
Product name: Thymopentin
Packaging: 5mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 30119
Product name: Thymopentin
Packaging: 10mg
Price: $62
Updated: 2024/03/01

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Thymopentin Chemical Properties,Usage,Production

Description

Thymopentin is a kind of peptide. Peptides and polypeptides play a critical role in the immune system and are therefore predestined as a source for new approaches in immunotherapy. Thymopentin is capable of modulating the immune response. It is a fragment of the thymopoietins (TMPOs) which is a family of nuclear protein. Studies have shown that Thymopentin is capable of affecting the function of T cells and monocytes monitored by increased cGMP level and the triggering of cellular signaling. It is also capable of improve an imbalanced immune system. As an immunomodulating agent, it is clinically used in the treatment of autoimmune diseases such as atopic dermatitis, chronic lymphocytic leukemia, Sezary’s syndrome, rheumatoid arthritis and decreased immune competency. Recent study has also shown that its immuno-modulating effect can also help fight against the infection of mycobacterium tuberculosis.

Originator

Janssen (Belgium)

Uses

Thymopentin Acetate (TP-5) is a synthetic immunomodulating pentapeptide.

Uses

immunoregulator

Definition

ChEBI: Thymopentin is an oligopeptide.

brand name

SINTOMODULINA; TIMUNOX

Clinical Use

Thymopentin is a synthetic, immunomodulating pentapeptide, representing the active fragment of the thymus hormone, thymopoietin. Thymopentin induces phenotypic differentiation and maturation of T-cells. It appears of value in the treatment of primary immune deficiency, rheumatoid arthritis, atopic dermatitis, sarcoidosis and a variety of other diseases with manifestations of disturbed immune balance.

References

Zhang, Yan, et al. "Novel thymopentin release systems prepared from bioresorbable PLA–PEG–PLA hydrogels." International journal of pharmaceutics 386.1 (2010): 15-22.
Gonser, S., E. Weber, and G. Folkers. "Peptides and polypeptides as modulators of the immune response: thymopentin—an example with unknown mode of action." Pharmaceutica Acta Helvetiae 73.6 (1999): 265-273.
Wang, Ying, et al. "Synthetic modifications of the immunomodulating peptide thymopentin to confer anti-mycobacterial activity." Biomaterials 35.9 (2014): 3102-3109.

Thymopentin Preparation Products And Raw materials

Raw materials

AMBERLITE(R) IRC-50 SEPHADEX G-75 ANION EXCHANGE RESIN 717

Preparation Products

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Thymopentin Suppliers

China 370 Europe 2 Germany 4 India 1 Switzerland 1 United Kingdom 7 United States 36 Global 421

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View Lastest Price from Thymopentin manufacturers

Sinoway Industrial co., ltd.

Product: Thymopentin 69558-55-0
Price: US $0.00/KG
Min. Order: 2KG
Purity: 99% up
Supply Ability: 20tons
Release date: 2022-08-24

Shandong Huizhihan Supply Chain Co., Ltd

Product: Thymopentin (TP-5) 69558-55-0
Price: US $0.00-0.00/BOX
Min. Order: 1BOX
Purity: 99%
Supply Ability: 20T
Release date: 2024-11-12

Shandong Huizhihan Supply Chain Co., Ltd

Product: Thymopentin (TP-5) 69558-55-0
Price: US $0.00-0.00/BOX
Min. Order: 1BOX
Purity: 99%
Supply Ability: 20T
Release date: 2024-11-12

69558-55-0, ThymopentinRelated Search:

THYMOPOIETIN II (33-36) Thymosin α1 Thymosin beta 4 Sermorelin Nesiritide acetate Triptorelin acetate Pramlintide acetate GLP-1 (7-37) Eptifibatide Thymalfasin THYMOPENTIN 5,THYMOPOIETIN PENTAPEPTIDE,ARG-LYS-ASP-VAL-TYR,arg-lys-asp-val-tyr acetate,H-ARG-LYS-ASP-VAL-TYR-OH THYMOPOIETIN II (32-35) THYMOPOIETIN II (32-34) THYMOPOIETIN II (34-36) THYMOSIN BETA10 (HUMAN, RAT) GLY-GLU-GLN-ARG-LYS-ASP-VAL-TYR-VAL-GLN-LEU-TYR-LEU H-ARG-LYS-ASP-VAL-TYR-OET,ARG-LYS-ASP-VAL-TYR-OET H-SER-ASP-ALA-ALA-VAL-ASP-THR-SER-SER-GLU-ILE-THR-THR-LYS-ASP-LEU-LYS-GLU-LYS-LYS-GLU-VAL-VAL-GLU-GLU-ALA-GLU-ASN-OH

Thyopentin

Thymopent njection

32-36-Thymopoietin

L-Arg-L-Lys-L-Asp-L-Val-L-Tyr-OH

Thymopoietin II-(32-36)

ThyMopentin for Injection

TP-5

THYMOPENTIN

THYMOPENTIN 5

THYMOPOIETIN (32-36) (HUMAN, MOUSE)

THYMOPOIETIN II FRAGMENT (32-36)

THYMOPOIETIN I/II (32-36) (BOVINE)

THYMOPOIETIN PENTAPEPTIDE

Immunox

Sintomodulina

Thymopentin-FITC

Thymopoietin 32-36

Timunox

ARG-LYS-ASP-VAL-TYR

(ASP34)-THYMOPOIETIN III (32-36) (BOVINE)

H-ARG-LYS-ASP-VAL-TYR-OH

RKDVY

TP-5（Thymopentin）

Thymopentin TP-5

Thymopentine

THYMOPETIN

Arg-Lys-Asp-Val-Tyr-OH

Thymopoietin pentapeptide-Fluorescin-isothiocyanate

thymopentin pentapeptide

ThymopentinⅡ

Sibuxintramine

TP-5 / Thymopentin GMP (CFDA) CAS

L-Tyrosine, L-arginyl-L-lysyl-L-α-aspartyl-L-valyl-

(6S,9S,12S,15S,18S)-1,6-Diamino-9-(4-aminobutyl)-12-(carboxymethyl)-18-(4-hydroxybenzyl)-1-imino-15-isopropyl-7,10,13,16-tetraoxo-2,8,11,14,17-pentaazanonadecan-19-oic acid

Thymopentin USP/EP/BP

NH2-RKDVY-OH

69558-55-0 Thymopentin

Thymopeptide

ORF 15244 ORF15244

ORF-15244

TP 5 Thymopoietin pentapeptide

Winstrol Stanozolol 10mg Tablets

Thymopentin, 10 mM in DMSO

69558-55-0

9558-55-0

C30H49N9O9

C265H397O67N73

BioChemical

Amino Acids and Peptides

Biochemicals and Reagents

Peptides

Other Peptides

多肽

Inhibitors

IMMUNOX

Peptide

Amino Acid Derivatives