ChemicalBook > CAS DataBase List > FUMITREMORGIN C

FUMITREMORGIN C

Product Name
FUMITREMORGIN C
CAS No.
118974-02-0
Chemical Name
FUMITREMORGIN C
Synonyms
12α-Fumitremorgin C;12alpha-Fumitremorgin C;FuMitreMorgin CFuMitreMorg;Fumitremorgin C, from Aspergillus fumigatus;Fumitremorgin C, 98%, from Aspergillus fumigatus;Fumitremorgin C, Aspergillus. fumigatus - CAS 118974-02-0 - Calbiochem;(5aS,12S,14aS)-1,2,3,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione;(5aS,12S,14aS)-9-methoxy-12-(2-methylprop-1-en-1-yl)-1,2,3,5a,6,11,12,14a-octahydro-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione;5H,14H-Pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione,1,2,3,5a,6,11,12,14a-octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-,(5aS,12S,14aS)-
CBNumber
CB7498129
Molecular Formula
C22H25N3O3
Formula Weight
379.45
MOL File
118974-02-0.mol
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FUMITREMORGIN C Property

Melting point:
259.5-260.5℃
Boiling point:
642.9±55.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
acetonitrile: 5 mg/mL, soluble
form 
solid
pka
17.16±0.40(Predicted)
color 
White to light brown
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2941900000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F9054
Product name
Fumitremorgin C
Purity
from Neosartorya fischeri, film
Packaging
250μG
Price
$260
Updated
2024/03/01
Sigma-Aldrich
Product number
344847
Product name
Fumitremorgin C, Aspergillus. fumigatus - CAS 118974-02-0 - Calbiochem
Purity
A cell-permeable indolyldiketopiperazinyl mycotoxin that inhibits BCRP/ABCG2 (breast cancer resistance protein/ATP-binding cassette G2) multidrug transport activity.
Packaging
250μg
Price
$272
Updated
2024/03/01
Cayman Chemical
Product number
11030
Product name
Fumitremorgin C
Purity
≥98%
Packaging
250μg
Price
$212
Updated
2024/03/01
Cayman Chemical
Product number
11030
Product name
Fumitremorgin C
Purity
≥98%
Packaging
1mg
Price
$547
Updated
2024/03/01
TRC
Product number
F862680
Product name
Fumitremorgin C
Packaging
5mg
Price
$2110
Updated
2021/12/16
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FUMITREMORGIN C Chemical Properties,Usage,Production

Uses

Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has determined fumitremorgin C as a potent inhibitor of the breast cancer resistance protein BCRP/ABCG2 multidrug transporter.

Definition

ChEBI: An organic heteropentacyclic compound that is a mycotoxic indole alkaloid produced by several fungi. A potent and specific inhibitor of the breast cancer resistance protein multidrug transporter.

General Description

A cell-permeable indolyldiketopiperazinyl mycotoxin that inhibits BCRP/ABCG2 (breast cancer resistance protein/ATP-binding cassette G2) multidrug transport activity. Also acts as a potent and specific chemosenzitizing agent.

Biochem/physiol Actions

Cell permeable: yes

target

Antifection | P-gp

storage

+4°C

FUMITREMORGIN C Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from FUMITREMORGIN C manufacturers

Career Henan Chemical Co
Product
FUMITREMORGIN C 118974-02-0
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
10kg
Release date
2018-12-18

118974-02-0, FUMITREMORGIN CRelated Search:


  • Fumitremorgin C, Aspergillus. fumigatus - CAS 118974-02-0 - Calbiochem
  • FuMitreMorgin CFuMitreMorg
  • (5aS,12S,14aS)-1,2,3,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione
  • 12alpha-Fumitremorgin C
  • 5H,14H-Pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione,1,2,3,5a,6,11,12,14a-octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-,(5aS,12S,14aS)-
  • Fumitremorgin C, 98%, from Aspergillus fumigatus
  • 12α-Fumitremorgin C
  • Fumitremorgin C, from Aspergillus fumigatus
  • (5aS,12S,14aS)-9-methoxy-12-(2-methylprop-1-en-1-yl)-1,2,3,5a,6,11,12,14a-octahydro-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione
  • 118974-02-0