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ML417

Product Name
ML417
CAS No.
1386162-69-1
Chemical Name
ML417
Synonyms
ML417;ML417, 10 mM in DMSO;2-{4-[2-(4-methoxyphenoxy)ethyl]piperazine-1-carbonyl}-1H-indole;(1H-indol-2-yl)(4-(2-(4-methoxyphenoxy)ethyl)piperazin-1-yl)methanone;Methanone, 1H-indol-2-yl[4-[2-(4-methoxyphenoxy)ethyl]-1-piperazinyl]-;neuroprotection,dopaminergic,β-arrestin,ML417,ML-417,translocation,phosphorylation,neurons,ML 417,Inhibitor,Dopamine Receptor,inhibit
CBNumber
CB76183003
Molecular Formula
C22H25N3O3
Formula Weight
379.45
MOL File
1386162-69-1.mol
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ML417 Property

Boiling point:
613.3±55.0 °C(Predicted)
Density 
1.231±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 2mg/mL, clear
form 
Solid
pka
16.11±0.30(Predicted)
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0128977
Product name
ML417
Purity
99.65%
Packaging
5mg
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-0128977
Product name
ML417
Purity
99.65%
Packaging
10mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-0128977
Product name
ML417
Purity
99.65%
Packaging
50mg
Price
$450
Updated
2021/12/16
DC Chemicals
Product number
DC33653
Product name
ML417
Packaging
250mg
Price
$950
Updated
2021/12/16
DC Chemicals
Product number
DC33653
Product name
ML417
Packaging
1g
Price
$1900
Updated
2021/12/16
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ML417 Chemical Properties,Usage,Production

Biological Activity

ML417 is a blood-brain barrier permeable, potent and highly selective agonist of D3 dopamine receptor (D3R) with very limited cross-reactivity at other GPCRs. ML417 potently induces G-protein activation, D3R-mediated b-arrestin translocation and pERK phosphorylation. It does not activate other dopamine receptors. ML417 protect D3R-expressing dopaminergic neurons from 6-OHDA induced cell death.

ML417 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML417 Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58

1386162-69-1, ML417Related Search:


  • ML417
  • Methanone, 1H-indol-2-yl[4-[2-(4-methoxyphenoxy)ethyl]-1-piperazinyl]-
  • neuroprotection,dopaminergic,β-arrestin,ML417,ML-417,translocation,phosphorylation,neurons,ML 417,Inhibitor,Dopamine Receptor,inhibit
  • (1H-indol-2-yl)(4-(2-(4-methoxyphenoxy)ethyl)piperazin-1-yl)methanone
  • 2-{4-[2-(4-methoxyphenoxy)ethyl]piperazine-1-carbonyl}-1H-indole
  • ML417, 10 mM in DMSO
  • 1386162-69-1