ChemicalBook > CAS DataBase List > ML417
ML417
- Product Name
- ML417
- CAS No.
- 1386162-69-1
- Chemical Name
- ML417
- Synonyms
- ML417;ML417, 10 mM in DMSO;2-{4-[2-(4-methoxyphenoxy)ethyl]piperazine-1-carbonyl}-1H-indole;(1H-indol-2-yl)(4-(2-(4-methoxyphenoxy)ethyl)piperazin-1-yl)methanone;Methanone, 1H-indol-2-yl[4-[2-(4-methoxyphenoxy)ethyl]-1-piperazinyl]-;neuroprotection,dopaminergic,β-arrestin,ML417,ML-417,translocation,phosphorylation,neurons,ML 417,Inhibitor,Dopamine Receptor,inhibit
- CBNumber
- CB76183003
- Molecular Formula
- C22H25N3O3
- Formula Weight
- 379.45
- MOL File
- 1386162-69-1.mol
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ML417 Property
- Boiling point:
- 613.3±55.0 °C(Predicted)
- Density
- 1.231±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 2mg/mL, clear
- form
- Solid
- pka
- 16.11±0.30(Predicted)
- color
- Off-white to light yellow
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0128977
- Product name
- ML417
- Purity
- 99.65%
- Packaging
- 5mg
- Price
- $90
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0128977
- Product name
- ML417
- Purity
- 99.65%
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0128977
- Product name
- ML417
- Purity
- 99.65%
- Packaging
- 50mg
- Price
- $450
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC33653
- Product name
- ML417
- Packaging
- 250mg
- Price
- $950
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC33653
- Product name
- ML417
- Packaging
- 1g
- Price
- $1900
- Updated
- 2021/12/16
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ML417 Chemical Properties,Usage,Production
Biological Activity
ML417 is a blood-brain barrier permeable, potent and highly selective agonist of D3 dopamine receptor (D3R) with very limited cross-reactivity at other GPCRs. ML417 potently induces G-protein activation, D3R-mediated b-arrestin translocation and pERK phosphorylation. It does not activate other dopamine receptors. ML417 protect D3R-expressing dopaminergic neurons from 6-OHDA induced cell death.
ML417 Preparation Products And Raw materials
Raw materials
Preparation Products
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ML417 Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6391
- Advantage
- 58
- Tel
- +1-+1(833)-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
- 58
- Tel
- support@targetmol.com
- Country
- United States
- ProdList
- 38631
- Advantage
- 58
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