ChemicalBook > CAS DataBase List > Bis(2-chloroethyl)amine hydrochloride

Bis(2-chloroethyl)amine hydrochloride

Product Name
Bis(2-chloroethyl)amine hydrochloride
CAS No.
821-48-7
Chemical Name
Bis(2-chloroethyl)amine hydrochloride
Synonyms
BIS(2-CHLOROETHYL)AMMONIUM CHLORIDE;CyclophosphaMide Related CoMpound A;is(2-chloroethyl)aMine hydrochloride;2-Chloro-N-(2-chloroethyl)ethylamine hydrochloride;nc26;sk555;tl161;leo72a;Eparina;nsc10873
CBNumber
CB7675423
Molecular Formula
C4H10Cl3N
Formula Weight
178.49
MOL File
821-48-7.mol
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Bis(2-chloroethyl)amine hydrochloride Property

Melting point:
212-214 °C(lit.)
storage temp. 
Store below +30°C.
solubility 
>100g/l
form 
Crystalline Powder
color 
White to beige
Water Solubility 
SOLUBLE
Sensitive 
Hygroscopic
BRN 
3550356
CAS DataBase Reference
821-48-7(CAS DataBase Reference)
NIST Chemistry Reference
2,2'-Dichlorodiethylamine hydrochloride(821-48-7)
EPA Substance Registry System
Ethanamine, 2-chloro-N-(2-chloroethyl)-, hydrochloride (821-48-7)
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Safety

Hazard Codes 
Xi,T,C
Risk Statements 
36/37/38-36-34
Safety Statements 
26-45-36/37/39-27
RIDADR 
2811
WGK Germany 
3
RTECS 
IA1225000
Hazard Note 
Irritant/Toxic
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29211980
Toxicity
LD50 orally in Rabbit: 1150 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B38503
Product name
Bis(2-chloroethyl)amine hydrochloride
Purity
98%
Packaging
25g
Price
$64.1
Updated
2024/03/01
Sigma-Aldrich
Product number
B38503
Product name
Bis(2-chloroethyl)amine hydrochloride
Purity
98%
Packaging
100g
Price
$79.1
Updated
2024/03/01
Sigma-Aldrich
Product number
8.20159
Product name
Bis(2-chloroethyl)ammonium chloride
Purity
for synthesis
Packaging
100g
Price
$53.4
Updated
2024/03/01
TCI Chemical
Product number
B1210
Product name
Bis(2-chloroethyl)amine Hydrochloride
Purity
>99.0%(T)
Packaging
25g
Price
$23
Updated
2024/03/01
TCI Chemical
Product number
B1210
Product name
Bis(2-chloroethyl)amine Hydrochloride
Purity
>99.0%(T)
Packaging
100g
Price
$65
Updated
2024/03/01
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Bis(2-chloroethyl)amine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white to beige crystalline powder

Uses

A cytotoxic metabolite of Cyclophosphamide; a deuterated analog of Nor-nitrogen mustard.

Uses

Bis(2-chloroethyl)amine hydrochloride is used as an intermediate in chemicals synthesis and building block for piperazine derivatives.

Safety Profile

A poison by inhalation,intraperitoneal, intramuscular, and subcutaneous routes.An experimental teratogen. Human mutation datareported. When heated to decomposition it emits toxicfumes of NH3, NOx, and Cl-.

Purification Methods

Crystallise the salt from Me2CO or MeOH/Et2O. The picrate has m 112-113o (from EtOH or Me2CO). [Mann J Chem Soc 464 1934, Ward J Am Chem Soc 57 915 1935,

Bis(2-chloroethyl)amine hydrochloride Preparation Products And Raw materials

Raw materials

Diethanolamine

Preparation Products

1-(3-METHYLPHENYL)PIPERAZINE N-(3-Trifluoromethylphenyl)piperazine 1-AMINO-4-(2-HYDROXYETHYL)PIPERAZINE 1-(4-Methoxyphenyl)piperazine dihydrochloride 1-CYCLOPROPYLPIPERAZINE 1-(3-NITROPHENYL)-PIPERAZINE 3-(4-methylpiperazin-1-yl)phenylboronic acid 1-(2-Methoxyphenyl)piperazine hydrobromide 1-(4-Methoxyphenyl)piperazine 3-(4-PHENYL-PIPERAZIN-1-YL)-PROPIONIC ACID 1-(4-METHYLPHENYL)PIPERAZINE 1-(3-Chlorophenyl)piperazine dihydrochloride Thiomorpholine 1-(2-ETHOXYPHENYL)PIPERAZINE HYDROCHLORIDE 4-(4-Methylpiperazin-1-yl)phenylboronic Acid 1-(4-Chlorophenyl)piperazine 4-CYANO-4-PHENYLPIPERIDINE HYDROCHLORIDE 1-(2-Methylphenyl)piperazine 1-(1-PHENYLETHYL)PIPERAZINE (4-PHENYL-PIPERAZIN-1-YL)-ACETIC ACID Tert-butyl bis(2-chloroethyl)carbamate 1-(3-FLUOROPHENYL)PIPERAZINE 1-[2-(MORPHOLIN-4-YL)-ETHYL]-PIPERAZINE N-(2-Methylphenyl)piperazine hydrochloride 1-(3,4-Dichlorophenyl)piperazine 1-(2-FLUOROPHENYL)PIPERAZINE HYDROCHLORIDE 1-(3-Methoxyphenyl)piperazine 1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE 1-(3,5-DICHLOROPHENYL)PIPERAZINE
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Bis(2-chloroethyl)amine hydrochloride Suppliers

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View Lastest Price from Bis(2-chloroethyl)amine hydrochloride manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Bis-(2- chloroethyl) Amine hydrochloride 821-48-7
Price
US $75.00-25.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-28
Moxin Chemicals
Product
Cyclophosphamide Impurity 821-48-7
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98
Supply Ability
1000000000
Release date
2024-12-10
Jinan Finer Chemical Co., Ltd
Product
Bis(2-chloroethyl)amine hydrochloride 821-48-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
≥99%
Supply Ability
100mt/year
Release date
2021-09-03

821-48-7, Bis(2-chloroethyl)amine hydrochlorideRelated Search:

DIETHANOLAMINE HYDROCHLORIDE 2-Aminoethylammonium chloride Methoxyammonium chloride DIETHYLALUMINUM CHLORIDE Cysteamine hydrochloride Diethylamine Bis(2-ethylhexyl)amine 2-(2-Aminoethylamino)ethanol N,N-Diisopropylethylamine Dimethylamine hydrochloride DICLOSULAM Aniline Topotecan hydrochloride p-Phenylenediamine dihydrochloride Bis(trimethoxysilylpropyl)amine BIS(4-BROMOPHENYL)AMINE 1-(3-Chlorophenyl)piperazine hydrochloride BIS(2-METHOXYETHYL)AMINE

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