4-BOCAMINO-NICOTINIC ACID
- Product Name
- 4-BOCAMINO-NICOTINIC ACID
- CAS No.
- 171178-34-0
- Chemical Name
- 4-BOCAMINO-NICOTINIC ACID
- Synonyms
- 4-BOCAMINO-NICOTINIC ACID;4-TERT-BUTOXYCARBONYLAMINO-NICOTINIC ACID;4-Tert-butoxycarbonylamino-nicatinec acid;4-{[(tert-butoxy)carbonyl]aMino}pyridine-3-carboxylic acid;4-[(2-methylpropan-2-yl)oxycarbonylamino]pyridine-3-carboxylic acid;3-Pyridinecarboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-;4-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-pyridinecarboxylic acid
- CBNumber
- CB7692761
- Molecular Formula
- C11H14N2O4
- Formula Weight
- 238.24
- MOL File
- 171178-34-0.mol
4-BOCAMINO-NICOTINIC ACID Property
- Boiling point:
- 348.4±27.0 °C(Predicted)
- Density
- 1.293±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 1.70±0.36(Predicted)
- Appearance
- White to light yellow Solid
N-Bromosuccinimide Price
- Product number
- W3733
- Product name
- 4-Boc-Aminonicotinicacid
- Packaging
- 100mg
- Price
- $81
- Updated
- 2021/12/16
- Product number
- 072740
- Product name
- 4-Boc-Aminonicotinic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $159
- Updated
- 2021/12/16
- Product number
- AAA0007033
- Product name
- 4-BOC-AMINONICOTINIC ACID
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $214.2
- Updated
- 2021/12/16
- Product number
- 072740
- Product name
- 4-Boc-Aminonicotinic acid
- Purity
- 95+%
- Packaging
- 5g
- Price
- $1038
- Updated
- 2021/12/16
- Product number
- AAA0007033
- Product name
- 4-BOC-AMINONICOTINIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1085.7
- Updated
- 2021/12/16
4-BOCAMINO-NICOTINIC ACID Chemical Properties,Usage,Production
Synthesis
280115-84-6
171178-34-0
General procedure for the synthesis of 4-((tert-butoxycarbonyl)amino)nicotinic acid from methyl 4-((tert-butoxycarbonyl)amino)nicotinate: 4-((tert-butoxycarbonyl)amino)nicotinic acid methyl ester (6.02 g, 23.86 mmol) was dissolved in dioxane (100 mL), and an aqueous sodium hydroxide solution (0.970 N, 28.05 mL, 27.20 mmol ). The reaction mixture was heated to 60°C and held for 1 hr and subsequently cooled to room temperature. To the cooled mixture was added aqueous hydrochloric acid (1.03 M, 26.99 mL, 27.20 mmol) and then extracted with chloroform (5 x 100 mL). The organic phases were combined, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 4-((tert-butoxycarbonyl)amino)nicotinic acid as a creamy solid (4.70 g, 83% yield).
References
[1] Patent: WO2006/100310, 2006, A1. Location in patent: Page/Page column 34
[2] Patent: WO2005/32481, 2005, A2. Location in patent: Page/Page column 42-43
[3] Patent: WO2005/32481, 2005, A2. Location in patent: Page/Page column 42-43
4-BOCAMINO-NICOTINIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
4-BOCAMINO-NICOTINIC ACID Suppliers
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- Country
- India
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