4-(Boc-amino)pyridine

Product Name: 4-(Boc-amino)pyridine
CAS No.: 98400-69-2
Chemical Name: 4-(Boc-amino)pyridine
Synonyms: 4-(BOC-AMINO)PYRIDINE;N-BOC-4-AMINO-PYRIDINE;BOC-N-4-AMINO-PYRIDINE;Linagliptin Impurity 76;4-(Boc-amino)pyridine ,97%;tert-Butyl 4-pyridylcarbamate;N-(4-pyridyl) t-butyl carbamate;tert-Butyl N-(4-Pyridyl)carbamate;TERT-BUTYL (PYRIDIN-4-YL)CARBAMATE;tert-butyl N-(pyridin-4-yl)carbaMate
CBNumber: CB6176039
Molecular Formula: C10H14N2O2
Formula Weight: 194.23
MOL File: 98400-69-2.mol

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4-(Boc-amino)pyridine Property

Melting point:: 145-149 °C
Boiling point:: 252.7±13.0 °C(Predicted)
Density: 1.131±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to crystal
pka: 12?+-.0.70(Predicted)
color: White to Almost white
InChI: InChI=1S/C10H14N2O2/c1-10(2,3)14-9(13)12-8-4-6-11-7-5-8/h4-7H,1-3H3,(H,11,12,13)
InChIKey: DRZYCRFOGWMEES-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)NC1C=CN=CC=1

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Safety

Hazard Codes: Xn
Risk Statements: 22-43
Safety Statements: 36/37
WGK Germany: 3
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B3331
Product name: 4-(tert-Butoxycarbonylamino)pyridine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $87
Updated: 2025/07/31

TCI Chemical

Product number: B3331
Product name: 4-(tert-Butoxycarbonylamino)pyridine
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $323
Updated: 2025/07/31

TRC

Product number: B621190
Product name: 4-(Boc-amino)pyridine
Packaging: 5g
Price: $70
Updated: 2021/12/16

Matrix Scientific

Product number: 075637
Product name: 4-(Boc-amino)pyridine
Purity: 95+%
Packaging: 5g
Price: $22
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK178693
Product name: 4-(Boc-amino)pyridine
Purity: 97%
Packaging: 1g
Price: $24
Updated: 2021/12/16

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4-(Boc-amino)pyridine Chemical Properties,Usage,Production

Chemical Properties

White to light brown solid

Uses

4-(Boc-amino)pyridine is a protected derivative of the amino acid Pyridine, a heterocyclic compound that is commonly found in biological specimens (such as human red blood cells), and is used as a starting reagent and intermediate in the chemical and pharmaceutical industries.

Synthesis

504-24-5

24424-99-5

98400-69-2

At room temperature, 4-aminopyridine (600 mg, 6.36 mmol), 4-dimethylaminopyridine (DMAP, 600 μg, 5.00 μmol), di-tert-butyl dicarbonate (Boc2O, 1.57 mL, 7.00 mmol) and triethylamine (Et3N, 1 mL, 7.63 mmol) were suspended in anhydrous tetrahydrofuran (THF, 3 mL) in anhydrous tetrahydrofuran (THF, 3 mL) and the reaction was stirred under argon protection for 20 min. After completion of the reaction, the reaction mixture was diluted with dichloromethane (CH2Cl2, 5 mL) and washed with 0.1 N hydrochloric acid (5 mL). The organic layers were combined, dried with anhydrous magnesium sulfate (MgSO4), filtered and concentrated by rotary evaporation. Finally, the target product 4-(tert-butoxycarbonylamino)pyridine (S1w, 1.30 g, yield >99%) was purified as a white solid by column chromatography (eluent ratio 30:1 dichloromethane/methanol).

References

[1] Tetrahedron Letters, 2006, vol. 47, # 7, p. 1087 - 1091
[2] Organic and Biomolecular Chemistry, 2006, vol. 4, # 14, p. 2769 - 2771
[3] Chemistry Letters, 2010, vol. 39, # 11, p. 1127 - 1129
[4] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 9, p. 2114 - 2124
[5] Tetrahedron Letters, 2007, vol. 48, # 47, p. 8318 - 8322

4-(Boc-amino)pyridine Preparation Products And Raw materials

Raw materials

Hexane Di-tert-butyl dicarbonate Potassium carbonate Triethylamine Ethyl acetate Hydrochloric acid Dichloromethane 4-Aminopyridine

Preparation Products

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4-(Boc-amino)pyridine Suppliers

Americas 1 China 147 Europe 2 France 2 Germany 2 India 10 Japan 1 Spain 1 Switzerland 1 United Kingdom 3 United States 24 Global 194

Nanjing Habo Medical Technology Co., Ltd.

Tel: 025-85760892 13376080562
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J & K SCIENTIFIC LTD.

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Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
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Energy Chemical

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Beijing Ouhe Technology Co., Ltd

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JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
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Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
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Country: United States
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Tetranov Biopharm

Tel: 13526569071
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Country: China
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
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View Lastest Price from 4-(Boc-amino)pyridine manufacturers

Dideu Industries Group Limited

Product: 4-(Boc-amino)pyridine 98400-69-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-26

Career Henan Chemical Co

Product: 4-(Boc-amino)pyridine 98400-69-2
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: g/kg/T
Release date: 2019-12-18

98400-69-2, 4-(Boc-amino)pyridineRelated Search:

3-Aminopyridine Glycine tert-Butyl carbamate Methyl anthranilate Betaine 2-Aminopyridine Urethane Chromium picolinate 4-N-BOC-Aminopiperidine tert-Butyl carbazate ALTRENOGEST tert-Butyl glycinate tert-Butyl peroxybenzoate 4-Dimethylaminopyridine tert-Butyl 4-aminobenzoate Pyridine 4-Aminobenzoic acid tert-butyl thiazol-4-ylcarbamate

4-(Boc-amino)pyridine tert-Butyl N-(4-Pyridyl)carbamate

Pyridin-4-yl-carbaMic acid tert-butyl ester

N-BOC-4-AMINO-PYRIDINE

TERT-BUTYL (PYRIDIN-4-YL)CARBAMATE

4-(BOC-AMINO)PYRIDINE

4-(TERT-BUTOXYCARBONYLAMINO)PYRIDINE

Carbamic acid, 4-pyridinyl-, 1,1-dimethylethyl ester (9CI)

BOC-N-4-AMINO-PYRIDINE

tert-butyl N-(pyridin-4-yl)carbaMate

4-(Boc-amino)pyridine ,97%

4-<N-(tert-butyloxycarbonyl)amino>pyridine

N-(4-pyridyl) t-butyl carbamate

4-(tert-Butoxycarbonylamino)pyridine &gt

Carbamic acid, 4-pyridinyl-, 1,1-dimethylethyl ester

Carbamic acid, N-4-pyridinyl-, 1,1-dimethylethyl ester

tert-Butyl N-(4-Pyridyl)carbamate

4-(Boc-amino)pyridine ISO 9001：2015 REACH

Linagliptin Impurity 76

tert-Butyl 4-pyridylcarbamate

98400-69-2

Building Blocks

C9 to C46

Pyridines

Heterocyclic Building Blocks

CMLLYL

Heterocycles

Heterocyclic Compounds

N-BOC

Heterocycle-Pyridine series

amine