ChemicalBook > CAS DataBase List > Capillarisin

Capillarisin

Product Name: Capillarisin
CAS No.: 56365-38-9
Chemical Name: Capillarisin
Synonyms: Capillaris;CAPILLARISIN;CAPILLARISIN(RG);CAPILLARISIN hplc;Capillarisin std.;Capillarisin Standard;Capillarisin USP/EP/BP;5,7-Dihydroxy-2-(4-hydroxyphenoxy)-6-methoxychromen-4-one;5,7-Dihydroxy-2-(4-hydroxyphenoxy)-6-methoxy-4H-chromen-4-one;5,7-dihydroxy-2-(4-hydroxyphenoxy)-6-methoxy-1-benzopyran-4-one
CBNumber: CB7693122
Molecular Formula: C16H12O7
Formula Weight: 316.26
MOL File: 56365-38-9.mol

Less

Capillarisin Property

Melting point:: approximate 225℃ (dec.)
Boiling point:: 582.6±50.0 °C(Predicted)
Density: 1.551±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 6.37±0.40(Predicted)
color: Light yellow to yellow

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CHM0013960
Product name: CAPILLARISIN
Purity: 95.00%
Packaging: 5MG
Price: $501.42
Updated: 2021/12/16

AHH

Product number: MT-04373
Product name: Capillarisin
Purity: 98%
Packaging: 0.025g
Price: $336
Updated: 2021/12/16

Arctom

Product number: CFN90317
Product name: Capillarisin
Purity: ≥98%
Packaging: 5mg
Price: $468
Updated: 2021/12/16

Less

Capillarisin Chemical Properties,Usage,Production

Uses

Capillarisin, as a constituent from Artemisiae Capillaris herba, is found to exert anti-inflammatory and antioxidant properties. Capillarisin can be used for the research of asthma-mediated complications and can be a potential neuroprotectant against bupivacaine-induced neurotoxicity[1][2][3].

Definition

ChEBI: Capillarisin is a member of coumarins.

in vivo

Capillarisin (20 and 80 mg/kg; i.p.; 1 hour) pretreatment strongly inhibits NF-κB mediated genes (iNOS, COX-2)^[4].
Capillarisin significantly reduces the plasma leading nitrite production. Capillarisin markedly suppresses the adenosine 5'-triphosphate (ATP) in plasma and substance P in CFA-induced paw tissue^[4].

Animal Model:	ICR mice^[4]
Dosage:	20 and 80 mg/kg
Administration:	I.p.; 1 hour
Result:	Pretreatment strongly inhibited NF-κB mediated genes (iNOS, COX-2).

target

TLR | NF-kB | MAPK | STAT | TNF-α | IL Receptor | NO | PGE | AP-1 | ERK | NOS | COX | MMP(e.g.TIMP) | VEGFR | JNK | Bcl-2/Bax

References

[1] Peng G, et al. Capillarisin exerts antiasthmatic activity in neonatal rats via modulating the matrix remodeling. Pak J Pharm Sci. 2020;33(4(Supplementary)):1907-1915. PMID:33612476
[2] Komiya T, et al. Capillarisin, a Constituent from Artemisiae Capillaris Herba. Chemical and Pharmaceutical Bulletin, 1975
[3] Zhao T, Wang Q. Capillarisin protects SH-SY5Y cells against bupivacaine-induced apoptosis via ROS-mediated PI3K/PKB pathway. Life Sci. 2020;259:118279. DOI:10.1016/j.lfs.2020.118279
[4] Khan S, et al. Anti-hyperalgesic and anti-allodynic activities of capillarisin via suppression of inflammatory signaling in animal model. J Ethnopharmacol. 2014;152(3):478-486. DOI:10.1016/j.jep.2014.01.028

Capillarisin Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Capillarisin Suppliers

China 55 Japan 1 United Kingdom 4 United States 7 Global 67

Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
Advantage: 58

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 6905
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Shanghai ChengShao Biological Technology Co., Ltd.

Tel: 021-61847300 13341622919
Fax: 021-61847300
Email: shcss01@163.com
Country: China
ProdList: 4808
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Beijing OKA biological technology co., LTD

Tel: 010-62971590 18548936886
Fax: 010-62340519
Email: 3462612863@qq.com
Country: China
ProdList: 10063
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Henan Weituxi Chemical Technology Co., Ltd.

Tel: 0371-63284658 18135795563
Fax: QQ:2885349392
Email: 2885349392@qq.com
Country: China
ProdList: 9989
Advantage: 58

Zhejiang Lianshuo Biotechnology Co., Ltd.

Tel: 18616526224
Email: lianshuo@vip.126.com
Country: China
ProdList: 9607
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 18108052721
Email: 2850505130@qq.com
Country: China
ProdList: 5167
Advantage: 58

Hubei xin bonus chemical co. LTD

Tel: 86-13657291602
Fax: 027-59338440
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 22963
Advantage: 58

Shanghai Fusheng Industrial Co., LTD

Tel: 021-52961053 13524666654
Email: 3004902811@qq.com
Country: China
ProdList: 9724
Advantage: 58

Shanghai Bohu Biotechnology Co., LTD

Tel: 021-57763112 13585886131
Email: 3004987436@qq.com
Country: China
ProdList: 9692
Advantage: 58

Wuxi Helen Biotechnology Co., Ltd.,

Tel: 0510-85629785 18013409632
Fax: 0510-85625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 14081
Advantage: 58

Shanghai Hewu Biotechnology Co., LTD

Tel: 021-57886085 17317861055
Email: shhebio@126.com
Country: CHINA
ProdList: 7974
Advantage: 58

Foshan Treasure Biotechnology Co., Ltd

Tel: 0757-85921206 18520245316
Email: 2329783215@qq.com
Country: China
ProdList: 12661
Advantage: 58

Beijing PUXI Technology Co., Ltd

Tel: 400-8087372 13161114455
Email: puxi_sale@qq.com
Country: China
ProdList: 4990
Advantage: 58

Shanghai Moqi Biological Technology Co., LTD

Tel: 021-38218169 13681877033
Email: 2702713455@qq.com
Country: China
ProdList: 9997
Advantage: 58

Suzhou Zhixin Biotechnology Co., Ltd.

Tel: 0512-65118909 18100677375
Email: sales@szzxbio.com
Country: China
ProdList: 2993
Advantage: 58

Chengdu DeSiTe Biological Technology Co., Ltd

Tel: 17308096051
Email: 3001048290@qq.com
Country: China
ProdList: 6219
Advantage: 58

Taizhou Zhongzhi Biotechnology Co., Ltd

Tel: 13012344321
Email: 3995296515@qq.com
Country: China
ProdList: 8448
Advantage: 58

SHANGHAI KEAN TECHNOLOGY CO., LTD.

Tel: +8613817748580
Fax: 021-50175322
Email: cooperation@kean-chem.com
Country: China
ProdList: 40066
Advantage: 58

Shanghai Acmec Biochemical Technology Co., Ltd.

Tel: +86-18621343501; +undefined18621343501
Email: product@acmec-e.com
Country: China
ProdList: 33338
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

Biorbyt Ltd.

Tel: --
Fax: --
Email: info@biorbyt.com
Country: CHINA
ProdList: 6482
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Shanghai Yanjin Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: yanjinbio@163.com
Country: CHINA
ProdList: 6896
Advantage: 58

Rhenbo (Shanghai) Biochemical Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6333
Advantage: 58

Shanghai Guangrui Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 4273
Advantage: 58

Shanghai Yubai Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: rongbai_sh021@163.com
Country: CHINA
ProdList: 6722
Advantage: 58

Shanghai Shifeng Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 2279790755@qq.com
Country: CHINA
ProdList: 5572
Advantage: 58

Xiamen Research Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1562893815@qq.com
Country: CHINA
ProdList: 6936
Advantage: 58

Shanghai Wowu Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: shhebio@126.com
Country: CHINA
ProdList: 6137
Advantage: 58

Xiamen Huijia Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6973
Advantage: 58

Shanghai Junrui Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: junruishengwu@163.com
Country: CHINA
ProdList: 6009
Advantage: 58

Shanghai yiji industries Co., Ltd.

Tel: --
Fax: --
Email: yiji01@foxmail.com
Country: China
ProdList: 6021
Advantage: 50

Wuhan Qiongge Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 1214415300@qq.com
Country: CHINA
ProdList: 5475
Advantage: 58

Shanghai Machine Pure Industrial Co., Ltd.

Tel: --
Fax: --
Email: 3245176082@qq.com
Country: CHINA
ProdList: 6800
Advantage: 58

Beijing Mairuibo Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 2926922538@qq.com
Country: CHINA
ProdList: 1791
Advantage: 58

Shanghai Zeye Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: shzeysw@163.com
Country: CHINA
ProdList: 6548
Advantage: 58

Shanghai Lianmai Biological Engineering Co., Ltd.

Tel: --
Fax: --
Email: shlmai@163.com
Country: CHINA
ProdList: 6055
Advantage: 58

Boppard-China

Tel: --
Fax: --
Email: info@boppard.cn
Country: China
ProdList: 687
Advantage: 58

Shanghai Jingke Chemical Technology Co., Ltd.

Tel: --
Fax: --
Email: jingkehuaxue@163.com
Country: CHINA
ProdList: 6141
Advantage: 58

56365-38-9, CapillarisinRelated Search:

(3-Methoxyphenyl)acetonitrile CHROMONE 3-(METHOXYMETHOXY)BENZALDEHYDE 4-Methoxyphenylacetic acid (Trifluoromethoxy)benzene o-Anisaldehyde m-Anisyl alcohol Anisole p-Anisaldehyde 2',3',4'-TRIHYDROXYACETOPHENONE 2,3,4-Trihydroxybenzaldehyde O-EUGENOL 3-Methoxysalicylaldehyde 2,5-Dimethoxybenzaldehyde 1-(2-HYDROXY-3,6-DIMETHOXYPHENYL)ETHAN-1-ONE 1,1-DIMETHOXYETHENE 2-METHOXY-BENZENE-1,3,5-TRIOL DIPHENOXYMETHANE

CAPILLARISIN

Capillarisin std.

CAPILLARISIN(RG)

CAPILLARISIN hplc

5,7-Dihydroxy-2-(4-hydroxyphenoxy)-6-methoxychromen-4-one

5,7-Dihydroxy-2-(4-hydroxyphenoxy)-6-methoxy-4H-chromen-4-one

2-(4-Hydroxyphenoxy)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one

5,7-Dihydroxy-2-(4-hydroxyphenoxy)-6-methoxy-4H-1-benzopyran-4-one

Capillaris

5,7-dihydroxy-2-(4-hydroxyphenoxy)-6-methoxy-1-benzopyran-4-one

Capillarisin Standard

4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenoxy)-6-methoxy-

Capillarisin USP/EP/BP

56365-38-9

Flavones