Methyl 2-amino-5-bromonicotinate
- Product Name
- Methyl 2-amino-5-bromonicotinate
- CAS No.
- 50735-34-7
- Chemical Name
- Methyl 2-amino-5-bromonicotinate
- Synonyms
- 2-AMINO-5-BROMONICOTINATE;METHYL 2-AMINO-5-BROMONICOTINAT;METHYL 2-AMINO-5-BROMONICOTINATE;2-AMino-5-broMo-nicotinic acid ethyl ester;2-AMINO-5-BROMO-NICOTINIC ACID METHYL ESTER;METHYL 2-AMINO-5-BROMOPYRIDINE-3-CARBOXYLATE;Methyl 2-amino-5-bromonicotinate ISO 9001：2015 REACH;3-Pyridinecarboxylic acid, 2-aMino-5-broMo-, Methyl e;TIANFU-CHEM Methyl 2-amino-5-bromonicotinate 50735-34-7;3-Pyridinecarboxylic acid, 2-aMino-5-broMo-, Methyl ester
- CBNumber
- CB7700860
- Molecular Formula
- C7H7BrN2O2
- Formula Weight
- 231.05
- MOL File
- 50735-34-7.mol
Methyl 2-amino-5-bromonicotinate Property
- Melting point:
- 143-146°C
- Boiling point:
- 275.2±35.0 °C(Predicted)
- Density
- 1.662±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 2.45±0.49(Predicted)
- Appearance
- White to yellow Solid
- InChI
- InChI=1S/C7H7BrN2O2/c1-12-7(11)5-2-4(8)3-10-6(5)9/h2-3H,1H3,(H2,9,10)
- InChIKey
- POWKBBOOIZBIRZ-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=C(Br)C=C1C(OC)=O
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933399990
N-Bromosuccinimide Price
- Product number
- 283940
- Product name
- Methyl 2-Amino-5-bromonicotinate
- Packaging
- 250mg
- Price
- $358
- Updated
- 2021/12/16
- Product number
- M285720
- Product name
- Methyl2-Amino-5-bromonicotinate
- Packaging
- 5g
- Price
- $415
- Updated
- 2021/12/16
- Product number
- OR110269
- Product name
- Methyl2-amino-5-bromonicotinate
- Packaging
- 5g
- Price
- $435
- Updated
- 2021/12/16
- Product number
- 4H58-9-16
- Product name
- Methyl 2-amino-5-bromonicotinate
- Packaging
- 5G
- Price
- $480
- Updated
- 2021/12/16
- Product number
- HCH0026318
- Product name
- METHYL 2-AMINO-5-BROMONICOTINATE
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $791.52
- Updated
- 2021/12/16
Methyl 2-amino-5-bromonicotinate Chemical Properties,Usage,Production
Uses
Methyl 2-Amino-5-bromonicotinate is a chemical reagent used in the synthesis of pharmaceutical agents.
Synthesis
14667-47-1
50735-34-7
To a stirred solution of methyl 2-aminopyridine-3-carboxylate (2 g, 13.15 mmol) and sodium bicarbonate (2.2 g, 26.31 mmol) in dichloromethane (30 mL) was slowly added a dichloromethane solution of bromine dropwise (1.01 mL bromine dissolved in 20 mL dichloromethane). The reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the reaction was quenched with sodium bisulfite solution (50 mL). The reaction mixture was extracted with dichloromethane (2 x 40 mL) and the combined organic phases were washed with brine (40 mL) and dried over anhydrous sodium sulfate. After filtration, the solvent was evaporated under reduced pressure to give methyl 2-amino-5-bromopyridine-3-carboxylate as a yellow solid (3 g, 99% yield).LCMS m/z (79Br/81Br) 231/233 (M+H)+.
References
[1] Patent: US2017/29420, 2017, A1. Location in patent: Paragraph 0034
Methyl 2-amino-5-bromonicotinate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 2-amino-5-bromonicotinate Suppliers
- Tel
- --
- Fax
- --
- info@abcr.de
- Country
- Germany
- ProdList
- 6831
- Advantage
- 75
View Lastest Price from Methyl 2-amino-5-bromonicotinate manufacturers
- Product
- Methyl 2-amino-5-bromonicotinate 50735-34-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-02-12
- Product
- Methyl 2-amino-5-bromonicotinate 50735-34-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-08-31
- Product
- Methyl 2-amino-5-bromonicotinate 50735-34-7
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30