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Triethyl orthoacetate

Description Reference
Product Name
Triethyl orthoacetate
CAS No.
78-39-7
Chemical Name
Triethyl orthoacetate
Synonyms
TEOA;1,1,1-TRIETHOXYETHANE;Ethane, 1,1,1-triethoxy-;ETHYL ORTHOACETATE;TRIETHYL-O-ACETATE;Triethylorthoacetat;triethyl ester orthoacetic acid;ETHYL O-ACETATE;Triethyl proacetate;TRIETHYL ORTHACETATE
CBNumber
CB7702576
Molecular Formula
C8H18O3
Formula Weight
162.23
MOL File
78-39-7.mol
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Triethyl orthoacetate Property

Boiling point:
142 °C (lit.)
Density 
0.885 g/mL at 25 °C (lit.)
vapor pressure 
3.4 hPa (20 °C)
RTECS 
KJ4075000
refractive index 
n20/D 1.396(lit.)
Flash point:
97 °F
storage temp. 
Store below +30°C.
solubility 
soluble in Chloroform, Ethyl Acetate
form 
Liquid
color 
Clear colorless to slightly yellow
explosive limit
0.9-7.0%(V)
Water Solubility 
SLIGHTLY SOLUBLE
Sensitive 
Moisture Sensitive
BRN 
506201
LogP
2.6 at 20℃
CAS DataBase Reference
78-39-7(CAS DataBase Reference)
NIST Chemistry Reference
Ethane, 1,1,1-triethoxy-(78-39-7)
EPA Substance Registry System
Ethane, 1,1,1-triethoxy- (78-39-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
10-36/38
Safety Statements 
26-37/39-16
RIDADR 
UN 3272 3/PG 3
WGK Germany 
1
Autoignition Temperature
455 °C
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29159080
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.20934
Product name
Triethyl orthoacetate
Purity
for synthesis
Packaging
50mL
Price
$28.6
Updated
2024/03/01
Sigma-Aldrich
Product number
8.20934
Product name
Triethyl orthoacetate
Purity
for synthesis
Packaging
100mL
Price
$35.9
Updated
2024/03/01
Sigma-Aldrich
Product number
8.20934
Product name
Triethyl orthoacetate
Purity
for synthesis
Packaging
500mL
Price
$73.2
Updated
2024/03/01
Sigma-Aldrich
Product number
75580
Product name
Triethyl orthoacetate
Purity
purum, ≥98.0% (GC)
Packaging
100ml
Price
$45.6
Updated
2024/03/01
Sigma-Aldrich
Product number
75580
Product name
Triethyl orthoacetate
Purity
purum, ≥98.0% (GC)
Packaging
500ml
Price
$125
Updated
2024/03/01
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Triethyl orthoacetate Chemical Properties,Usage,Production

Description

Triethyl orthoacetate is the ethyl orthoester of acetic acid. It is an oily liquid with a pungent odor. Triethyl orthoacetate is used as a water scavenger and as intermediate for synthesis of pharmaceuticals. It is used in organic synthesis for the introduction of the acetate group to an alcohol and in the Johnson-Claisen rearrangement.

Reference

  • J. S. Lindsey, I. C. Schreiman, H. C. Hsu, P. C. Kearney, A. M. Marguerettaz, Rothemund and Adler-Longo reactions revisited: synthesis of tetraphenylporphyrins under equilibrium conditions, The Journal of Organic Chemistry, 1987, vol. 52, pp. 827-836
  • R. C. Capozza, Polymeric orthoesters housing beneficial drug for controlled release therefrom, Patent US4066747A

Chemical Properties

clear colourless liquid

Uses

Intermediate.

Uses

Triethyl orthoacetate is used as pharmaceutical and water scavenger. It is also used in organic synthesis to introduce the acetate group into an alcohol. It is involved in the Johnson-Claisen rearrangement.

Hazard

Moderate fire risk.

Flammability and Explosibility

Flammable

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View Lastest Price from Triethyl orthoacetate manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Triethyl Orthoacetate 78-39-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-04-11
Henan Fengda Chemical Co., Ltd
Product
Triethyl orthoacetate 78-39-7
Price
US $31.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-22
Wuhan Han Sheng New Material Technology Co.,Ltd
Product
Triethyl orthoacetate 78-39-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2023-06-07

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