4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester

ChemicalBook > CAS DataBase List > 4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester

4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester

Appearance

Product Name: 4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester
CAS No.: 206989-61-9
Chemical Name: 4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester
Synonyms: tert-Butyl 4-acetylpiperidine-1-carboxylate;1-Boc-4-acetyL;N-Boc-4-Acetypiperidine;Zanubrutinib Impurity 6;N-Boc-4-acetylpiperidine;Zanubrutinib impurity-22;1-BOC-4-ACETYL-PIPERIDINE;-N-Boc-4-Acetylpiperidine;1-N-Boc-4-Acetylpiperidine;1-BOC-ESTER4-ACETYL-PIPERIDINE
CBNumber: CB7704363
Molecular Formula: C12H21NO3
Formula Weight: 227.3
MOL File: 206989-61-9.mol

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4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester Property

Boiling point:: 312.4±35.0 °C(Predicted)
Density: 1.052±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: -2.23±0.40(Predicted)
InChI: InChI=1S/C12H21NO3/c1-9(14)10-5-7-13(8-6-10)11(15)16-12(2,3)4/h10H,5-8H2,1-4H3
InChIKey: HNVBBNZWMSTMAZ-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCC(C(C)=O)CC1

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN 2811 6.1 / PGIII
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed
Precautionary statements: P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SYX00409
Product name: tert-Butyl 4-acetylpiperidine-1-carboxylate
Packaging: 1g
Price: $29.8
Updated: 2024/03/01

TRC

Product number: T135528
Product name: tert-Butyl 4-acetylpiperidine-1-carboxylate
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Apolloscientific

Product number: OR321452
Product name: tert-Butyl 4-acetylpiperidine-1-carboxylate
Purity: 98%
Packaging: 1g
Price: $15
Updated: 2021/12/16

Oakwood

Product number: 048392
Product name: N-Boc-4-Acetylpiperidine
Purity: 98%
Packaging: 250mg
Price: $15
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-LS
Product name: N-Boc-4-acetyl piperidine
Packaging: 1g
Price: $24
Updated: 2021/12/16

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4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester Chemical Properties,Usage,Production

Appearance

Light yellow oil

Uses

tert-Butyl 4-Acetylpiperidine-1-carboxylate is a useful research chemical.

Synthesis

Tert-butyl-4-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate (2.29 g, 8.32 mmol) was dissolved in 30 ml of tetrahydrofuran (THF), and the resulting solution was cooled to -78 °C. To the solution, methylmagnesium bromide (3.0 M) (7.73 ml, 10.82 mmol) was slowly added, and the solution was stirred at 0 °C for 1 hr. After the reaction was completed with a 2 N hydrochloric acid aqueous solution, 6 N sodium hydroxide solution was added to adjust the pH to 10. Then the solution was extracted with dichloromethane. The organic layer was treated with magnesium sulfate (MgSO4) and filtered, and the solution was concentrated. The resulting residue was isolated and purified by silica gel column chromatography (dichloromethane/methanol = 10/1) to give 4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester (6.36 g, 94.0 percent).

4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester manufacturers

Career Henan Chemical Co

Product: N-Boc-4-piperidineacetate 206989-61-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 500kg
Release date: 2018-08-17

206989-61-9, 4-Acetyl-piperidine-1-carboxylic acid tert-butyl esterRelated Search:

1-Piperidinecarboxylic acid, 4-[3-(dimethylamino)-1-oxo-2-propen-1-yl]-, 1,1-dim Propanedinitrile, 2-[hydroxy(4-phenoxyphenyl)Methylene]- Propanedinitrile, 2-[Methoxy(4-phenoxyphenyl)Methylene]- tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 4,5,6,7-tetrahydro-2-(4-phenoxyphenyl)-7-(4-piperidinyl)-, (7S)- (R)-Zanubrutinib 4-PHENOXYBENZOIC ACID Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 4,5,6,7-tetrahydro-2-(4-phenoxyphenyl)-7-(4-piperidinyl)- Zanubrutinib 1-Boc-hexahydro-1H-azepin-4-amine 1-Boc-4-cyanopiperidine 3-AMINO-1-[(1,1-DIMETHYLETHOXY)CARBONYL]-3-PIPERIDINEACETIC ACID METHYL ESTER tert-butyl 6-hydroxy-3-azabicyclo[3.1.0]hexane-3-carboxylate tert-butyl 4-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate tert-Butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate hydrochloride 2-OXO-2,5-DIHYDRO-PYRROLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

4-ACETYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

1-N-Boc-4-Acetylpiperidine

N-Boc-4-acetylpiperidine

1-tert-Butoxycarbonyl-4-acetylpiperidine

1-Piperidinecarboxylic acid, 4-acetyl-, 1,1-dimethylethyl ester

1-BOC-4-ACETYL-PIPERIDINE

N-Boc-4-Acetypiperidine

tert-Butyl 4-acetylpiperidine-1-carboxylate

1-BOC-ESTER4-ACETYL-PIPERIDINE

4-acetyl-piperidine-1-carboxylic acid Mono t-butyl ester

4-acetyl-1-piperidinecarboxylic acid tert-butyl ester

tert-butyl 4-ethanoylpiperidine-1-carboxylate

4-acetyl-1-(t-butoxycarbonyl)piperidine

1-Boc-4-acetyL

Zanubrutinib Related Compound 4

Zanubrutinib Impurity 6

-N-Boc-4-Acetylpiperidine

7-(1-benzoylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Zanubrutinib benzoyl amide impurity

Zanubrutinib impurity-22

206989-61-9

206979-61-9

C12H20NO4