ORIENTIN
- Product Name
- ORIENTIN
- CAS No.
- 28608-75-5
- Chemical Name
- ORIENTIN
- Synonyms
- LUTEOLIN-8-C-GLUCOSIDE;Polygonin;Luteolin 8-C-β-D-glucopyranoside;lutexin;ORIENTIN;ORIENTINE;Aids026706;Aids-026706;ORIENTIN(P);ORIENTIN,NA
- CBNumber
- CB7710333
- Molecular Formula
- C21H20O11
- Formula Weight
- 448.38
- MOL File
- 28608-75-5.mol
ORIENTIN Property
- Melting point:
- 260-285°C
- Boiling point:
- 816.1±65.0 °C(Predicted)
- Density
- 1.759±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- 1 M NaOH: soluble1mg/mL, clear, yellow-orange
- pka
- 6.24±0.40(Predicted)
- form
- powder
- color
- yellow
- Stability:
- Hygroscopic
- LogP
- 1.580 (est)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- RTECS
- DJ3009300
- HS Code
- 29389090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- O9765
- Product name
- Orientin
- Purity
- ≥97% (HPLC)
- Packaging
- 1mg
- Price
- $134
- Updated
- 2024/03/01
- Product number
- 03810585
- Product name
- Orientin
- Purity
- primary pharmaceutical reference standard
- Packaging
- 10mg
- Price
- $677
- Updated
- 2024/03/01
- Product number
- 25143
- Product name
- Orientin
- Purity
- ≥95%
- Packaging
- 25mg
- Price
- $61
- Updated
- 2024/03/01
- Product number
- 25143
- Product name
- Orientin
- Purity
- ≥95%
- Packaging
- 50mg
- Price
- $95
- Updated
- 2024/03/01
- Product number
- O9765
- Product name
- Orientin
- Purity
- ≥97% (HPLC)
- Packaging
- 5mg
- Price
- $496
- Updated
- 2024/03/01
ORIENTIN Chemical Properties,Usage,Production
Description
Orientin is a flavone glycoside originally isolated from P. orientale that has diverse biological activities, including antioxidant, antibacterial, and anti-inflammatory properties. Orientin scavenges 2,2-diphenyl-1-picryl-hydrazyl (DPPH; ) radicals with an IC50 value of 316.21 μg/ml. It also decreases the cytopathic effects of parainfluenza type 3 virus with an IC50 value of 11.7 μg/ml and a cytotoxic concentration (CC50) value of 375 μg/ml in Hep-2 cells. Orientin (5-40 μM) inhibits LPS-induced barrier disruption, decreases the expression of toll-like receptor 4 (TLR4), phosphorylated p38, and NF-κB, and decreases TNF-α production and IL-6 secretion in a dose-dependent manner in human umbilical vein endothelial cells (HUVECs). It also prolongs survival in a mouse model of LPS-induced lethal endotoxemia when administered at a dose of 36 μg/animal 12 hours after LPS administration.
Chemical Properties
Yellow powder
Uses
Orientin is a flavone, a chemical flavonoid compound. Orientin have been investigated for its anti-oxidant, antihypertensive and antihyperlipidemic effects.
Definition
ChEBI: A C-glycosyl compound that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 8.
ORIENTIN Preparation Products And Raw materials
Raw materials
Preparation Products
ORIENTIN Suppliers
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- 86-21-61259102
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View Lastest Price from ORIENTIN manufacturers
- Product
- Orientin 28608-75-5
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-12-04
- Product
- Orientine 28608-75-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Orientine 28608-75-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09