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ORIENTIN

Product Name
ORIENTIN
CAS No.
28608-75-5
Chemical Name
ORIENTIN
Synonyms
LUTEOLIN-8-C-GLUCOSIDE;Polygonin;Luteolin 8-C-β-D-glucopyranoside;lutexin;ORIENTIN;ORIENTINE;Aids026706;Aids-026706;ORIENTIN(P);ORIENTIN(SH)
CBNumber
CB7710333
Molecular Formula
C21H20O11
Formula Weight
448.38
MOL File
28608-75-5.mol
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ORIENTIN Property

Melting point:
260-285°C
Boiling point:
816.1±65.0 °C(Predicted)
Density 
1.759±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
1 M NaOH: soluble1mg/mL, clear, yellow-orange
pka
6.24±0.40(Predicted)
form 
powder
color 
yellow
Stability:
Hygroscopic
LogP
1.580 (est)
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Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
DJ3009300
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
O9765
Product name
Orientin
Purity
≥97% (HPLC)
Packaging
1mg
Price
$134
Updated
2024/03/01
Sigma-Aldrich
Product number
03810585
Product name
Orientin
Purity
primary pharmaceutical reference standard
Packaging
10mg
Price
$677
Updated
2024/03/01
Cayman Chemical
Product number
25143
Product name
Orientin
Purity
≥95%
Packaging
25mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
25143
Product name
Orientin
Purity
≥95%
Packaging
50mg
Price
$95
Updated
2024/03/01
Sigma-Aldrich
Product number
O9765
Product name
Orientin
Purity
≥97% (HPLC)
Packaging
5mg
Price
$496
Updated
2024/03/01
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ORIENTIN Chemical Properties,Usage,Production

Description

Orientin is a flavone glycoside originally isolated from P. orientale that has diverse biological activities, including antioxidant, antibacterial, and anti-inflammatory properties. Orientin scavenges 2,2-diphenyl-1-picryl-hydrazyl (DPPH; ) radicals with an IC50 value of 316.21 μg/ml. It also decreases the cytopathic effects of parainfluenza type 3 virus with an IC50 value of 11.7 μg/ml and a cytotoxic concentration (CC50) value of 375 μg/ml in Hep-2 cells. Orientin (5-40 μM) inhibits LPS-induced barrier disruption, decreases the expression of toll-like receptor 4 (TLR4), phosphorylated p38, and NF-κB, and decreases TNF-α production and IL-6 secretion in a dose-dependent manner in human umbilical vein endothelial cells (HUVECs). It also prolongs survival in a mouse model of LPS-induced lethal endotoxemia when administered at a dose of 36 μg/animal 12 hours after LPS administration.

Chemical Properties

Yellow powder

Uses

Orientin is a flavone, a chemical flavonoid compound. Orientin have been investigated for its anti-oxidant, antihypertensive and antihyperlipidemic effects.

Definition

ChEBI: A C-glycosyl compound that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 8.

ORIENTIN Preparation Products And Raw materials

Raw materials

Preparation Products

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ORIENTIN Suppliers

Canada 1 China 194 Europe 1 France 2 Germany 5 India 2 Japan 2 South Korea 1 United Kingdom 7 United States 21 Global 236
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
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View Lastest Price from ORIENTIN manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Orientin 28608-75-5
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-12-04
Zhuozhou Wenxi import and Export Co., Ltd
Product
Orientine 28608-75-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Orientine 28608-75-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

28608-75-5, ORIENTINRelated Search:

4-N-HEXYLPHENOL 5-ETHYL-2-HYDROXY-BENZALDEHYDE 1-(2-Hydroxy-5-methylphenyl)ethanone 4-Phenylbutanol ORIENTIN 4'-Hydroxy-3'-methylacetophenone (S)-(-)-3-BENZYLOXY-1,2-PROPANEDIOL 1-(3-METHYLPHENYL)ETHANOL (S)-(+)-1-Phenyl-1,2-ethanediol (S)-(+)-4-PHENYL-2-BUTANOL 1,2,3-HEPTANETRIOL 2-Benzyloxyethanol 2',4'-DIHYDROXY-3'-PROPYLACETOPHENONE 4-Hexylresorcinol Vitexin 1-O-BENZYL-RAC-GLYCEROL 2',4'-DIHYDROXY-3'-METHYLACETOPHENONE HOMOORIENTIN(ISOORIENTIN)(P)

  • 2-(3,4-Dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
  • ORIDONIN (RG)
  • 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-.beta.-D-glucopyranosyl-5,7-dihydroxy-
  • Aids026706
  • Aids-026706
  • 8-Glucosylluteolin
  • ORIENTIN
  • ORIENTINE
  • LUTEOLIN-8-C-GLUCOSIDE
  • Orientin, froM PolygonuM orientale
  • Orientin,Lutexin
  • Orientin, 98%, from Polygonum orientale L.
  • 2-(3,4-dihydroxyphenyl)-8-beta-d-glucopyranosyl-5,7-dihydroxy-4h-1-benzopyra
  • 4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-8-beta-d-glucopyranosyl-5,7-dihy
  • luteolin8-glucoside
  • lutexin
  • orientin(flavone)
  • ORIENTIN(P)
  • ORIENTIN(SH)
  • ORIENTIN WITH HPLC
  • 8-β-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone
  • Luteolin 8-C-β-D-glucopyranoside
  • 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-(β-D-glucopyranosyl)-4H-1-benzopyran-4-one
  • 2-(3,4-Dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
  • Polygonin
  • Orientin, 98%, from Polygonum orientale
  • 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-
  • 8-beta-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone
  • Luteolin 8-C-beta-D-Glucopyranoside
  • ORIENTIN USP/EP/BP
  • 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one
  • OrientinQ: What is Orientin Q: What is the CAS Number of Orientin Q: What is the storage condition of Orientin Q: What are the applications of Orientin
  • 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-8-b-D-glucopyranosyl-5,7-dihydroxy-
  • 28608-75-5
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Aromatics, Glucuronides, Pharmaceuticals, Intermediates & Fine Chemicals