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EXO1

Product Name
EXO1
CAS No.
461681-88-9
Chemical Name
EXO1
Synonyms
EXO1;EOX 1;hExoI;hExo1;Exo 1,Exo1;Exonuclease 1;EXOCYTIC INHIBITOR 1;4-FLUORO-BZ-2-ABZ-OME;2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE;Exo-1, Vesicular trafficking inhibitor
CBNumber
CB7713354
Molecular Formula
C15H12FNO3
Formula Weight
273.26
MOL File
461681-88-9.mol
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EXO1 Property

Melting point:
132-134℃
Boiling point:
415.2±45.0 °C(Predicted)
Density 
1.246±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
DMSO: 19 mg/mL, soluble
form 
solid
pka
-1.09±0.10(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

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N-Bromosuccinimide Price

Tocris
Product number
1850
Product name
Exo 1
Purity
≥99%(HPLC)
Packaging
10
Price
$123
Updated
2021/12/16
Tocris
Product number
1850
Product name
Exo 1
Purity
≥99%(HPLC)
Packaging
50
Price
$515
Updated
2021/12/16
TRC
Product number
E962510
Product name
Exo 1
Packaging
1mg
Price
$45
Updated
2021/12/16
Usbiological
Product number
255279
Product name
Exo 1
Packaging
10mg
Price
$366
Updated
2021/12/16
Usbiological
Product number
480471
Product name
Exo 1
Packaging
100ul
Price
$499
Updated
2021/12/16
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EXO1 Chemical Properties,Usage,Production

Uses

Exo1 is used in the synthetic preparation of tricyclic heterocyclic compounds as antagonists of tachykinin receptor (substance P receptor) for prevention and/or treatment of substance P-related diseases.

Definition

ChEBI: 2-[[(4-fluorophenyl)-oxomethyl]amino]benzoic acid methyl ester is a member of benzamides.

Biological Activity

Reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Modifies Golgi ADP-ribosylation factor (ARF)1 GTPase activity and inhibits exocytosis (IC 50 ~ 20 mM). Has similar, but not identical, action to brefeldin A (1,6,7,8,9,11ab,12,13,14,14aa-Decahydro-1b,13a-dihydroxy-6b-methyl-4H-cyclopent(f)oxacyclotridecin-4-one ).

EXO1 Preparation Products And Raw materials

Raw materials

Preparation Products

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EXO1 Suppliers

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461681-88-9, EXO1Related Search:

4-Fluorobenzylamine 4-Fluorobenzamide Methyl 2-(methylamino)benzoate EXO1 N-METHYLANTHRANILIC ACID METHYL 2-ACETAMIDOBENZOATE (4-FLUORO-BENZYL)-METHYL-AMINE N-Acetylanthranilic acid 4-FLUORO-N-METHYLBENZAMIDE exo-1,7,7-trimethylbicyclo(2.2.1)hept-2 3-epoxy-exo-norborna 1,7,7-trimethyl-,propanoate,exo-bicyclo[2.2.1]heptan-2- exo-enterotoxi exo-7-oxabicyclo(2.2.1)heptane-3-dicarboxylicanhydrid ,endo,exo 1,7,7-trimethyl-exo-Bicyclo[2.2.1]heptan-2-o 1,2,3,4,10,10-Hexachloro-6,7-Epoxy-1,4,4a,5,6,7,8,8a-octahydro-exo-1,4-exo-5,8-dimethanonaphthalene 7,7-trimethylbicyclo[2.2.1]hept-2-yl)oxy]-2-[(exo-ethan

  • EOX 1
  • EXOCYTIC INHIBITOR 1
  • EXO1
  • 4-FLUORO-BZ-2-ABZ-OME
  • 2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER
  • 2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE
  • Anti-EXO1, N-Terminal antibody produced in rabbit
  • Exonuclease 1
  • hExo1
  • hExoI
  • Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate
  • Exo 1,Exo1
  • 2-Pyridinecarboxylic acid, 3-(4-fluorobenzoyl)-6-methyl-, methyl ester
  • Exo-1, Vesicular trafficking inhibitor
  • 461681-88-9
  • C15H12FNO3
  • Signalling