EXO1
- Product Name
- EXO1
- CAS No.
- 461681-88-9
- Chemical Name
- EXO1
- Synonyms
- EXO1;EOX 1;hExoI;hExo1;Exo 1,Exo1;Exonuclease 1;EXOCYTIC INHIBITOR 1;4-FLUORO-BZ-2-ABZ-OME;2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE;Exo-1, Vesicular trafficking inhibitor
- CBNumber
- CB7713354
- Molecular Formula
- C15H12FNO3
- Formula Weight
- 273.26
- MOL File
- 461681-88-9.mol
EXO1 Property
- Melting point:
- 132-134℃
- Boiling point:
- 415.2±45.0 °C(Predicted)
- Density
- 1.246±0.06 g/cm3(Predicted)
- storage temp.
- Store at RT
- solubility
- DMSO: 19 mg/mL, soluble
- form
- solid
- pka
- -1.09±0.10(Predicted)
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P321Specific treatment (see … on this label).
N-Bromosuccinimide Price
- Product number
- J67103
- Product name
- Methyl 2-(4-fluorobenzamido)benzoate, 98%
- Packaging
- 10mg
- Price
- $109
- Updated
- 2021/12/16
- Product number
- 1850
- Product name
- Exo 1
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $123
- Updated
- 2021/12/16
- Product number
- 1850
- Product name
- Exo 1
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $515
- Updated
- 2021/12/16
- Product number
- E962510
- Product name
- Exo 1
- Packaging
- 1mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 255279
- Product name
- Exo 1
- Packaging
- 10mg
- Price
- $366
- Updated
- 2021/12/16
EXO1 Chemical Properties,Usage,Production
Uses
Exo1 is used in the synthetic preparation of tricyclic heterocyclic compounds as antagonists of tachykinin receptor (substance P receptor) for prevention and/or treatment of substance P-related diseases.
Definition
ChEBI: 2-[[(4-fluorophenyl)-oxomethyl]amino]benzoic acid methyl ester is a member of benzamides.
Biological Activity
Reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Modifies Golgi ADP-ribosylation factor (ARF)1 GTPase activity and inhibits exocytosis (IC 50 ~ 20 mM). Has similar, but not identical, action to brefeldin A (1,6,7,8,9,11ab,12,13,14,14aa-Decahydro-1b,13a-dihydroxy-6b-methyl-4H-cyclopent(f)oxacyclotridecin-4-one ).
EXO1 Preparation Products And Raw materials
Raw materials
Preparation Products
EXO1 Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71