ChemicalBook > CAS DataBase List > EXO1

EXO1

Product Name
EXO1
CAS No.
461681-88-9
Chemical Name
EXO1
Synonyms
EXO1;EOX 1;hExoI;hExo1;Exo 1,Exo1;Exonuclease 1;EXOCYTIC INHIBITOR 1;4-FLUORO-BZ-2-ABZ-OME;2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE;Anti-EXO1, N-Terminal antibody produced in rabbit
CBNumber
CB7713354
Molecular Formula
C15H12FNO3
Formula Weight
273.26
MOL File
461681-88-9.mol
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EXO1 Property

Melting point:
132-134℃
Boiling point:
415.2±45.0 °C(Predicted)
Density 
1.246±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
DMSO: 19 mg/mL, soluble
form 
solid
pka
-1.09±0.10(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J67103
Product name
Methyl 2-(4-fluorobenzamido)benzoate, 98%
Packaging
10mg
Price
$109
Updated
2021/12/16
Tocris
Product number
1850
Product name
Exo 1
Purity
≥99%(HPLC)
Packaging
10
Price
$123
Updated
2021/12/16
Tocris
Product number
1850
Product name
Exo 1
Purity
≥99%(HPLC)
Packaging
50
Price
$515
Updated
2021/12/16
TRC
Product number
E962510
Product name
Exo 1
Packaging
1mg
Price
$45
Updated
2021/12/16
Usbiological
Product number
255279
Product name
Exo 1
Packaging
10mg
Price
$366
Updated
2021/12/16
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EXO1 Chemical Properties,Usage,Production

Uses

Exo1 is used in the synthetic preparation of tricyclic heterocyclic compounds as antagonists of tachykinin receptor (substance P receptor) for prevention and/or treatment of substance P-related diseases.

Definition

ChEBI: 2-[[(4-fluorophenyl)-oxomethyl]amino]benzoic acid methyl ester is a member of benzamides.

Biological Activity

Reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Modifies Golgi ADP-ribosylation factor (ARF)1 GTPase activity and inhibits exocytosis (IC 50 ~ 20 mM). Has similar, but not identical, action to brefeldin A (1,6,7,8,9,11ab,12,13,14,14aa-Decahydro-1b,13a-dihydroxy-6b-methyl-4H-cyclopent(f)oxacyclotridecin-4-one ).

EXO1 Preparation Products And Raw materials

Raw materials

Preparation Products

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EXO1 Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
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021-65675885
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info@efebio.com
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China
ProdList
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TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
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China
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24131
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Tel
0512-65118909 15162312715
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sales@szzxbio.com
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Tel
18171815831
Email
1341138380@qq.com
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China
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2769
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Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
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sales@chemhifuture.com
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4030
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Nanjing Tengyi Biotechnology Co., Ltd
Tel
025-58851786 17714337195
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sales@tybiochem.com
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+86-18521732826
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market@aladdin-e.com
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Beijing Dongge Boye Biotechnology Co., Ltd.
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Absin Bioscience Inc.
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461681-88-9, EXO1Related Search:


  • EOX 1
  • EXOCYTIC INHIBITOR 1
  • EXO1
  • 4-FLUORO-BZ-2-ABZ-OME
  • 2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER
  • 2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE
  • Anti-EXO1, N-Terminal antibody produced in rabbit
  • Exonuclease 1
  • hExo1
  • hExoI
  • Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate
  • Exo 1,Exo1
  • 2-Pyridinecarboxylic acid, 3-(4-fluorobenzoyl)-6-methyl-, methyl ester
  • 461681-88-9
  • C15H12FNO3
  • Signalling